European Science Foundation's Forward Look reaches out beyond the endless frontiers
...-40 years). Developing such scenarios requires the involvement of both many scientific disciplines and a broad range of different stakeholders in the food chain. The scenarios activity will raise awareness within Europe about food security and other issues of societal concern and help structure the debate betwee...Gene predicts better outcome as cortex normalizes in teens with ADHD
... from several previous studies led them to suspect involvement of an ADHD-implicated version of a gene that codes for a receptor protein that binds to the brain chemical messenger dopamine. This version of the dopamine D4 receptor gene, called the 7-repeat variant, accounts for about 30 percent of the genetic ...Females more prone to brain damage from alcohol abuse
...eath in males. "What we're looking at now is the involvement of testosterone in mediating the cell death in females," Wiren said. "Not just in chronic conditions, but in acute (alcohol consumption) situations, testosterone levels drop in males. In females, they may rise." Wiren also wants to look at a longer...MIT IDs link between brain tumor proteins
...rrently deciphering. The new knowledge of c-Mets involvement could give researchers a potent tool to attack GBM tumors. When the MIT group treated tumor cells with drugs that inhibit EGFRvIII and c-Met, respectively, much lower doses were required to kill the cells than when either drug was given alone. Ther...Nodal status is best predictor of outcome after neoadjuvant therapy for esophageal cancer
... of staging, which takes into account tumour size, involvement of lymph nodes (nodal status), and presence or abs...esponses were compared with those who had no nodal involvement after neoadjuvant therapy, there was no significant difference in the 1, 3, and 5 year survival rate......threat emerging." Wells himself has had personal involvement in the sustainability process for fifteen years and suggests that, "It still feels as though we are collectively not prepared to ask the really difficult questions about what happens next if, as seems likely, all our efforts to head off a crisis come...2 MSU professors spearhead international water project
...s. The partnership will maximize opportunities for involvement of underrepresented minorities and women and will have an impact on future generations of scientists, according to Tarabara. When the nonrenewable five-year, grant expires, Tarabara said, the project will live on. We are working with industrial p...Turn-ons and turn-offs for neurons
...t-regulated gene expression can be used to analyze involvement of genes for example in cognition in the mouse, as was shown in key studies from 1996. But in spite of the published success, others scientists report some difficulties: in some experiments the full reactivation of Tet-regulated genes failed. Mazahir...PINK1 protects from Parkinson's
... unknown, pathological analyses have suggested the involvement of oxidative stress and mitochondrial dysfunction. Recently, an inherited form of early-onset PD has been linked to mutations in both copies of the gene encoding the mitochondrial protein PINK1. Furthermore, increasing evidence indicates that single-...Gene responsible for common hearing loss identified for first time
...h they already knew had non-genetic indications of involvement in otosclerosis: it plays a role during embryonic development of the ear and is expressed in otosclerotic bone. They used SNP (single nucleotide polymorphism) analysis, or looking at DNA sequence variations occurring in a single nucleotide, A, T, C ...PET/CT use expands: Effectively diagnosing graft infections
...odeoxyglucose or FDGcan effectively diagnose graft involvement and differentiate it from infection that affects only soft tissue infection in its vicinity," she added. These two processes are treated differently. Infection of a graft requires surgery to remove the involved implant, while infection of the soft ti...A close-up on pancreatic disease: How do we improve the odds?
...ul R0 resection was superior mesenteric vein (SMV) involvement on CT (OR 0.29) and the only significant predictor of unresectability on CT was periportal adenopathy (OR 3.42). No imaging features predicting node-positivity or vein resection were statistically significant and adding EUS to CT did not improve the...Jaap Sinninghe Damst awarded the Vernadsky Medal for innovative use of biomarkers
...knowledge to EUROCORES Through Sinninghe Damst's involvement in several different European Science Foundation (ESF) EUROCORES Programmes, it is clear how very versatile these biomarkers are as they can be applied to a whole range of scientific projects. "Being involved with EUROCORES has been a nice opportu...Study shows response to financial loss parallels brain's processing of pain
...ments have had difficulty eliciting the striatum's involvement in losses," says Read Montague, PhD, at the Baylor College of Medicine, who did not participate in the research. In the study, 24 subjects13 male and 11 femalelearned to associate abstract image cues with a specific amount of money: 50 pence (equiv...Scientists identify new strategy for preventing acute and chronic brain disease
... up totally new ways of thinking about tau and its involvement in neurological disease." Because overstimulation of brain cells contributes to a variety of major neurological diseases, these findings may have broad therapeutic implications. "We still have hurdles to cross before this discovery is translated ...Breast cancer milieu -- Progression, tamoxifen sensitivity, and DNA reversion
...l site to other locations. Fibulin-2s potential involvement in breast cancer spread may provide prognostic imp...hekhar MPV, Santner S, Carolin KA, Tait L. Direct involvement of breast tumor fibroblasts in the modulation of tamoxifen sensitivity. Am J Pathol 2007 170:154615...FSU pushing boundaries with environmentally friendly community
...iversity College of Engineering who will lead CAPS involvement in Sky. "This project has the potential to serve as a model for future developments throughout the United States." The focus of Cartes excitement is Sky, a 571-acre community being planned by the development company White Starr Inc. on land it owns...Discoveries thrust cancer-initiating stem cells into a larger role in cancer biology and treatment
...dictor of breast cancer, we were interested in the involvement of the gene in stem cells," said Suling Liu, Ph.D., a researcher at the University of Michigans Comprehensive Cancer Center. "If mammary stem cells are, indeed, the driving force of breast cancer, then we need to know more about their function if we ...Scientists find new genes for Crohn's disease
...y (pronounced AU-TOF-A-GEE ). Finding ATG16L1's involvement in Crohn's disease provides confirmatory evidence for what doctors have long suspected: that an individual's ability to respond effectively to harmful microbes influences his or her susceptibility to the disease. "We propose that genetic variation ......e to learn more about the three proteins and their involvement in cAMP regulation. The researchers added additional copies of the three genes to the cells to increase the levels of the proteins, and then used a laboratory technique called RNA intereference to turn off production of the proteins. Of the thr...