Tag: "irinotecan" at biology news
Other highlights in the November 3 JNCI
...am combined with genotyping could help to optimize irinotecan
chemotherapy, according to a new study. Irinotecan...1 genotyping could assist with the optimization of irinotecan
chemotherapy. The method is currently undergoing validation in a prospective study. Contact: Nationa...
Data confirm panitumumab single-agent antitumor activity in patients with mCRC
...d with 5FU (with or without leucovorin) and either irinotecan
or oxaliplatin, or both. Patients received 2.5 mg/kg of panitumumab by weekly one-hour intravenous infusion without premedication. Tumor responses were confirmed no less than four weeks after the initial response was observed. In this Phase 2 study, ...
Calls for improved screening of colorectal cancer in Europe's aging population at ECCO 13
... to the 'infused' FOLFIRI regimen. In this study, irinotecan
in combination with either the Nordic fortnightly ...ies. The precise treatment schedule with FLIRI was irinotecan
180 mg/m2 on day 1, 5FU 500 mg/m2 bolus iv on day 1 and 2, plus FA 60 mg/m2 on days 1 and 2. In cont...
Univ. of Chicago researchers license pharmacogenomics test for patients with colorectal cancer to Mayo
...s are likely to have a serious adverse reaction to irinotecan
hydrochloride (Camptosar), a key component of the ...nowledge of an individual's risk for toxicity from irinotecan
by revealing whether patients have one of two common versions of a gene that encodes for a protein i...
Study finds racial differences in response to treatments for advanced colon cancer
...ent to receive two of three drugs; 5 Fluorouracil, irinotecan
or oxaliplatin. The 1,412 participants reported on in this study all had advanced colorectal cancer. Blacks were similar to whites in extent of disease, gender, age-range and prior treatment. But blacks had a "significantly lower response rate" ove...
UK markey cancer center receives FDA approval to test novel cancer drug
...used drugs topotecan (ovarian and lung cancer) and irinotecan
(colon cancer). At the time of DB-67's initial development and testing, pharmaceutical company Novartis licensed the drug. But after Burke died, the company released its licensing of DB-67, leaving the drug with a dismal future. However, as a pediatr...
Cetuximab and irinotecan combination increases survival in metastatic colorectal cancer
...a combination of the drugs cetuximab (Erbitux) and irinotecan
showed a significant improvement in progression-free survival over just irinotecan
alone, according to an international team of researchers. The Erbitux Plus Irinotecan in Colorect...
St. Jude shows gene test not needed if cancer drug given in low doses
...arch Hospital have shown that when the cancer drug irinotecan
is given in low doses for multiple days, it elimin...se once a month, children can begin treatment with irinotecan
immediately. Irinotecan is used to treat childhood solid tumors such as neuroblastoma, sarcomas and ...