Female gender provides an advantage in renal diseases
...ells located around the small blood vessels of the kidneys (cultured mesangial cells). She and her colleagues found that: the female hormone estradiol inhibited the activity of transforming growth factor (TGF-]); TGF-] promotes scarring of the kidney in many renal diseases. estradiol does thi...A gene that protects from kidney disease
...lp develop effective, noninvasive therapies. The kidneys are the organs that help our body dispose of poten... understood. NPHP is such a disease; it causes the kidneys to degenerate and shrink starting early on in childhood often leading to renal failure before the ag...Nanotechnology, medicine and bioethics
... as artificial tissues that could replace diseased kidneys and livers, and even repair nerve damage. In addition, although the research is still exploratory, scientists are beginning to build nanostructures that mimic complex biomolecules. Some of these engineered structures appear to have regenerative po...New report explores nanotechnology's future
...e as artificial tissues that will replace diseased kidneys and livers, and even repair nerve damage. "Nanotechnology can be used very effectively to extract critical information about the inception of the disease process at the level of the molecule and the atom, and as such, it presents us with a huge horiz...Will nanotechnology revolutionize medicine?
... as artificial tissues that would replace diseased kidneys and livers, and even repair nerve damage; and to integrate nanodevices with the nervous system to create implants that restore vision and hearing, and build new prosthetic limbs. On Monday, April 23, 2007 Dr. Samuel I. Stupp, a leading nanomedic...JCI table of contents: April 2, 2007
...contrast, in the adult most EPO is produced by the kidneys but some is produced by liver cells known as hepatocytes, particularly when levels of oxygen in the body are low. The role of two related proteins, HIF-1 and HIF-2 in EPO production by hepatocytes had been controversial. But now, researchers from the...Something fishy in human blood could save lives
...reatments will help people with damaged livers and kidneys remove toxic ammonia from their bloodstream. "Rh proteins are important targets for treatment of high toxic blood ammonia levels that occur in liver disease," said Shigehisa Hirose, co-author of the study. "Our findings also indicate that the ammon...Ewwwww! UCLA anthropologist studies evolution's disgusting side
...and anuses ranked the most disgusting, while hips, kidneys and arteries turned the fewest stomachs. "The disgust we feel when we consider individual body parts reflects an adaptive goal of avoiding the transfer of pathogens," Fessler said. The same logic appears to be behind some of the queasiness experi...New reference material for diagnosing kidney disease
... (GFR), which provides an estimate of how well the kidneys are removing waste and excess fluid from the blood. GFR cannot be measured directly in a clinical setting, so instead physicians test for blood serum levels of creatinine, a metabolic by-product of muscles. Plugging the creatinine level into an equat...Nicotine: The link between cigarette smoking and kidney disease progression?
...gial cells (MC) cells in the blood vessels of the kidneys are endowed with nicotinic receptors (nAChRs) 4, 5, 7, 2, 3, 4 and 5 (cells that interact with the nicotine in tobacco) and may play an active role in the development of certain kidney diseases. The Study The study, "Nicotine: The Link Between...Climate change has surprising effect on endangered naked carp
... to river-water fish. Ammonia-N secretion by the kidneys declines by a surprising 70 percent, and urine flow decreases drastically to less than 5 percent of its rate in the freshwater river water. "In other words, the kidney changed from an organ which excreted water at a greater rate than salt in river-...UVA receives training grant for new kidney disease researchers
...a. "We hope these new researchers may identify why kidneys fail and how to cure or reverse kidney diseases through the development of new treatment and therapies to improve the quality of life of millions of people who suffer from kidney disease." Nephrology is one of many specialty areas which are experien...NIH selects Purdue to use phi29 DNA packaging motor for National Nanomedicine Development Center
...Anything smaller would be filtered out through the kidneys too quickly to be effective, and larger molecules would not be able to enter cells." The team plans to attach the nanomotor to a lipid sheet, cell membrane and liposome. A liposome is a pocket made up of fat molecules. The liposome would, in effect...Genetic mutation explains form of brittle bone disease
...t the body including the heart, blood vessels and kidneys defects in this process affecting these other tissues could be the cause of as-yet-undescribed connective tissue diseases, he said. In further studies, Lee and his colleagues are exploring the role of prolyl 3-hydroxylation in such disorders. Also...NIH funds Berkeley Lab research on defense against radiological attack
...th plutonium and allow it to be passed through the kidneys and excreted out of the body, a process known as "decorporation." The agents may also prove useful for removing radioactive waste from the environment. Raymond, former Chair of the Department of Chemistry of UC Berkeley, is the Director of CSD's G...Animal physiology conference sheds light on human physiology
... to consume a lot of it to get enough sugar. Their kidneys must get rid of all that water by filtering it ver...ey do that? "When hummingbirds are fasting, their kidneys stop filtering altogether," Martinez del Rio explained. "In mammals, when the kidney stops filtering...Amgen launches Aranesp prefilled Sureclick autoinjector for treatment of anemia
...ications such as anemia, which occurs when failing kidneys no longer produce sufficient erythropoietin, a hormone that stimulates the production of oxygen-carrying red blood cells. Red blood cells contain hemoglobin, a red, iron-rich protein that carries oxygen from the lungs to all of the body's tissues. O...Scientists explore how complex organs develop from a simple bud
...tal development. Research on this process in mouse kidneys generated a real-time tracking procedure which has significant implications for genetic manipulation. Ultimately, scientists hope analysis of branching morphogenesis will lead to the design of a computer program that is able to virtually reconstru...New company will seek drugs against diabetes and cancer
...etes. "People with diabetes can go blind, their kidneys can fail and their nerves can die," says Baranski. "We don't have any good drugs for counteracting these effects. We know that high blood sugar contributes to these problems, so I went to Ross and asked if his fruit fly system could uncover why high ......ty by relatively impermeable skin, and others have kidneys that can concentrate salts from large volumes of water or specialized glands that exude salt. Many are gray or black in color, which is believed to be an advantage because it matches the dark color of the soils often found in tidal marshes. Why endem...