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Rare immune cell is key to transplant's cancer-killing effect

... triggers a massive inflammatory reaction that can kill the patient, especially if he or she is older or has other medical problems." In an effort to eliminate GVHD, other researchers have suggested removing APCs from transplanted donor cells, according to Ferrara. "We know that APCs are involved in graft...

UCLA researchers identify how antibody blocks prostate cancer growth in animal models

...study. "Do antibodies recruit the immune system to kill the cancer or do they send a signal that tells the cancer cells to stop growing? This study shows how the antibody works, so we'll know how to apply it in the clinical setting." The 1G8 antibody has two parts, one that binds with PSCA and one that bi...

Restoring silenced suppressor gene kills lung-cancer cells

...ne in lung-cancer cells that don't express it will kill that lung-cancer cell," says coauthor Kay Huebner,...WOX gene can be delivered into tumor cells, it can kill them. "We also showed that if a silenced WWOX gene is present and can be turned back on, that too w...

New genetic test can detect clam disease

...in clams and other shellfish in New England do not kill the shellfish and will wash away once the red tide bloom diminishes, eventually making the shellfish safe to eat. QPX kills the clams, and there is no known cure. Gast is working with Roxanna Smolowitz, a veterinarian at the nearby Marine Biologi...

More males chimps means more territorial patrols, study shows

...r territory. Chimpanzees will sometimes attack and kill their neighbors during the rarely observed boundar...ck." During the attacks, the chimps beat and often kill their neighbors. The groups are generally all male, but on rare occasions females---typically infer...

A fatty acid found in milk may help control inflammatory diseases

... growth by treating the animal with antibiotics to kill bacteria and avoid activating the immune defense system, but this raises long-term concerns about developing antibiotic resistance," he adds. "You can also suppress the animal's immune system, but that makes it much more susceptible to disease." Howe...

USC neuroscientist to receive Prince of Asturias prize

... human genome; Judah Folkman, whodiscovered how to kill tumor cells by cutting off their bloodsupply; and AIDS virus co-discoverers Robert Gallo andLuc Montangier. The last winner of an undivided prize was primatologistJane Goodall in 2003. Winners in the other award categories - arts, socialsciences, l...

UCF researchers to develop water purification system for hurricane relief

...ocess is a naturally created nanoparticle that can kill bacteria that foul membranes used as filters to produce drinking water. In catastrophic situations such as Hurricane Katrina or the recent earthquake in Pakistan, the membranes become so fouled by bacteria that they become unusable for water treatmen...

Cornell finds natural selection in humans

...e population very harmful changes to proteins that kill or stop reproduction. But mutations that have led to slightly deleterious versions of the gene -- mutations that may cause disease or only slightly reduce the average number of children left by those that carried the mutation -- can by chance become...

Plant wounds trigger bacteria

... be susceptible to the disease, which can stunt or kill a plant. Grafting can also lead to infections. "There are really no chemicals, no sprays that can control this disease," said Tom Burr, a plant pathology professor at Cornell and an expert on crown gall disease. "This is really the cutting-edge resea...

NC State researchers redesign life for Mars and beyond

... If not reduced quickly, the toxic superoxide will kill plant cells.Since the superoxide reductase gene is not found in plants, Boss, an expert in plantmetabolism and plant responses to stimuli, and Grunden, an expert in organisms that grow inextreme environments, wanted to use this genetic manipulation a...

Protein aggregates in Lou Gehrig's disease linked to neuron death

...ted whether or not the protein aggregates actually kill the cells. Now a research team at Northwestern University, using mammalian neurons and live-cell time-lapse spectroscopy, has become the first to clearly link the presence of the ALS-associated mutant SOD1 protein aggregates with neuronal cell death...

MBL study shows how good cholesterol (HDLs) provide human immunity to certain parasites

...findings that two proteins work synergistically to kill the Nagana parasite in humans contradict a long-held hypothesis that a single protein was the key to HDL's parasite-fighting power. "The research may be helpful to veterinarians hoping to develop treatments to aid African cattle farmers, who lose thr...

UV measurement tool aids defense against microbes in tap water

...n critical for gauging the treatment's capacity to kill disease-causing bacteria or parasites before they ...rinking water, Linden said. Chlorine also fails to kill some infectious microbes, such as the protozoan parasite Cryptosporidium. Known as "Crypto," the par...

Biologists discover new pathway into plant cells

...t cell membranes, where it functions as a toxin to kill the cell. It had been known that viruses and bacteria can penetrate cell wall barriers and disrupt plant cells, but never before has a protein been found that could do this by itself. When more research is done, this may provide a new tool to penetra...

New ECCO studies highlight promising potential of cancer immunotherapy

...te to boosting anti-tumour T-cell reponses to help kill malignant cells. US investigator Dr Arkadiusz Dudek, from the University of Minnesota, and his team have developed a new method of vaccine-induced augmentation of tumour specific cytotoxic T-lymphocyte responses with the use of latex or silica beads....

Technique offers new view of dynamic biological landscape

... for yeast growth -- whose complete deletion would kill the cell -- the researchers invented a high throughput technique to manipulate the half-life of their messenger RNA (mRNA). Since mRNA is a genetic intermediate during the conversion of a gene to protein, reducing its lifespan by mutating the mRNA me...

Worm parasite may hold clues in bid for illness and allergy cures

...to switching off the response that would otherwise kill the parasites. If that is the case, then infections could be cured, not by vaccination or drug treatment, but by reactivating the immune system. It is the first time such a concept has been explored to curb the tropical diseases caused by helminths ...

Seal rookeries could provide a reliable food source for endangered California condors, study finds

...g the West Coast. "Condors eat carrion, they don't kill for food," says C. Page Chamberlain, lead author o...If they consume just a small lead fragment, it can kill them." For the PNAS study, the researchers focused on the dietary habits of condors, past and pres...

Can anthrax be controlled?

...s, play a key role in anthrax infections. They can kill Bacillus anthracis by producing a protein called a...ophils are white blood cells that can identify and kill microbes. In the skin, neutrophils takeup the spores, which germinate inside the neutrophil to a veg...

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(Date:11/23/2009)...ike frogs and toads have existed for 360 million y... new aquatic fungus is threatening to make many of...mber issue of Microbiology Today . , The fungu...d to be associated with waves of amphibian extinct...a in the 1990,s. Bd infects over 350 amphibian spe...
(Date:11/23/2009)... Institute of General Medical Sciences (NIGMS), pa...investing $42.3 million for grants in scientific a...NIH developed the GO grant program to stimulate bi...ided by the American Recovery and Reinvestment Act...that promise to have a significant impact on a fie...
(Date:11/23/2009)...y from Perth,s Telethon Institute for Child Health...iming of alcohol consumption in pregnancy affects ...as just been published online in the international...ary said the analysis was drawn from a random samp...ionnaire three months after the baby,s delivery, a...
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