UW scientists unravel critical genetic puzzle for flu virus replication
...enza A viruses package their genetic contents, and knowing that they do so systematically, suggests it may be possible, by manipulating key genetic elements, to quickly engineer viruses that can be used to mass produce vaccines. Researchers have been trying to make viral vectors using nine genetic segments, ...New software tool helps protect nation's drinking water
...ntionally introduced into a drinking water source, knowing what threat it posed to the public would be essential to the incident commanders charged with mounting an emergency response. "Incident commanders need timely and accurate information to guide their decisions on deploying first responders to best pr...MBL leads effort to update E. coli genome
...ory work on the unknown functions with the goal of knowing what every gene does in the living organism," said Riley. According to Riley, currently there is no funding by an agency for any kind of coordinated E. coli annotation effort, however interested members of the E. coli community are applying to NIH ...File compression can expand mammography's power
... radiologists, who can read the digitized versions knowing they will do at least as well as the original mammograms." The research paper will appear in today's (Dec. 20) issue of Radiology, the journal of the Radiological Society of North America. Lucier developed the file-compression method used in the stud...Scientists narrow the time limits for the human and chimpanzee split
...e," said Kumar. "There is considerable interest in knowing when we diverged from our closest relative among animal species," said Kumar, who is director of the Center for Evolutionary Functional Genomics in the Biodesign Institute at Arizona State University. "This divergence time also has considerable impo...'Fish with chips' reporting from ocean top highlights at Census of Marine Life mid-point
...ian rivers. Because manysalmon die in the ocean, knowing their usual travelsalong marine highways has far-reaching implicationsworldwide for authorities who determine when fisheriesshould be open or closed to conserve endangeredstocks. The salmon are implanted with almond-sized electronictags scanned by de...New technique helps researchers determine amino-acid charge
... electrostatics have on them, Grosman said, is not knowing the protonation state of ionizable residues. Protons, he added, are so small that they cannot be detected even with X-ray crystallographic approaches. For the study, Grosman and colleagues used protein engineering. They mutated each residue of the po......mic loaddiet." The key, they have found, may be in knowing a person's level ofinsulin secretion. "Insulin is a hormone that is important in glucose (sugar) metabolism,"explains senior author Andrew Greenberg, MD, director of the Obesity andMetabolism Laboratory at the Center. "The regulation of body weight i...Yale scientists decipher 'wiring pattern' of cell signaling networks
...l the pieces of an airplane separated out, and not knowing how those pieces function together to create an airplane and make it fly," said Snyder. "We wanted to know how the tens of thousands of proteins coordinate to carry out complex processes such as growth, cell division and formation of complex cell typ...MRI best tool for studying intricate nerves in dogs
...onance imaging (MRI) as a diagnostic modality. "By knowing the normal MRI anatomy of cranial nerve emergences in the dog, the clinician will better recognize lesions affecting those nerves, such as inflammatory or neoplastic diseases, thus allowing earlier recognition of the disease," states lead researcher ...Loss of fear factor makes timid mouse bold
...a was very likely to be involved, we had no way of knowing what the outcome would be." An indication that stathmin might contribute to fear came when they mapped the parts of the brain where the gene was most active. They found that stathmin was highly expressed not only in the amygdala, but also in other p...US Surgeon General urges Americans to know their family health history
...sease and promote personal health. It's clear that knowing your family history can save your life." Dr. Carmona released an updated, Web-based version of a free, computerized tool that organizes family health information into a printout that people can take to health-care professionals to help determine whe...Worms know bad food when they smell it
...arch of better food. So, the researchers surmised, knowing whether or not certain bacteria are toxic is something "worth learning" for the worm. To find out whether worms learn from experience to avoid or seek out certain types of bacteria, the researchers compared the behavior of three sets of worms. The ...UCLA discovery will aid in treatment of patients with a deadly brain cancer
...ancer patients treated at another facility without knowing who the responders were. They were able to independently replicate their results, confirming that those with both genetic variations were more likely to respond to EGFR blocking drugs. The study shows that glioblastoma patients can respond to targete...'New' science gleans knowledge from ancient lands and societies
... fall and rise of tuberculosis For Jane Buikstra, knowing more about what happened in ancient times can help humans deal with the present and plan for the future. Tuberculosis, one of nature's most enduring and adaptable infectious diseases, is an example. Tuberculosis (TB) has plagued humans and animals f...Study identifies several new bacterial species associated with common infection in women
...fferent species of bacterium," said Fredricks. "By knowing the sequence of the gene you can identify the bacterium. We get a sort of molecular bar code." With these read outs, researchers went online to the GenBank database operated by the National Institutes of Health and looked for matches among the bacter...Dramatic rise in number of authors publishing in open access journals, independent survey finds
...hors write "There has been a large rise in authors knowing quite a lot about open access (up 10 percentage po...ts from the 2004 figure) and a big fall in authors knowing nothing at all about open access (down 25 points)." Thirty percent of authors surveyed claimed to kn...ECCO 13 - One voice, one vision needed to overcome cancer in Europe
...ou become suddenly aware of your own mortality and knowing that your survival chances can potentially depend upon whether or not your local authorities can afford it is simply not good enough. It is becoming patently obvious that if something is not done about it soon, in the future your survival outlook wil...Haplotype map offers new insights into human disease, evolution
...ic responses remain largely unknown -- and because knowing this information is necessary for successful development of new approaches to prevention, diagnosis and treatment -- identifying the genetic contributors to human health is a fundamental goal for biomedicine. A new genomics-based approach to human g...Study provides insight into cellular defenses against genetic mutation
...da, Ph.D. "That is critically significant because, knowing the structure and role of CBP80, we can now seek to develop drug-based gene therapies that interfere with it in cases where NMD contributes to disease-causing protein shortages." Researchers may be able to convert mRNA quality control from NMD over t...