FDA approves ABRAXANE(TM) for metastatic breast cancer
...teristics and indications, marketing approvals and launches of other products, the impact of pharmaceutical industry regulation, the impact of competitive products and pricing, the availability and pricing of ingredients used in the manufacture of pharmaceutical products, the ability to successfully manufactu...Studies reveal methods viruses use to sidestep immune system
...HCV's tenaciousness. Once HCV infects the cell, it launches a counterattack against RIG-I, producing a protein called a protease to disrupt the cell's immune response that is otherwise turned on through RIG-I by the virus infection. The viral protease, NS3/4A, chops up essential signaling proteins involved in...SSRI antidepressants involve dopamine as well as serotonin signaling
...ne-triggered firing from such neurons, in essence, launches two different types of neuronal ammunition, causing "cosignaling." The researchers were led to study the role of dopamine signaling in SSRI action by previous evidence that dopamine was involved in depression and in the function of antidepressants in...News tips: NASA presentations at Annual 2005 Joint Assembly Meeting
...was formed in summer 2004 to coordinate ozonesonde launches during the multi-site, multi-aircraft campaign called ICARTT/INTEX/NEAQS (International Consortium on Atmospheric Research on Transport and Transformation / Intercontinental Transport Experiment/New England Air Quality Study). The study region was do...Immune cells' genetic 'jam session' is controlled by cell division machinery
... Hopkins report that the band leader that normally launches the DNA-copying machinery to start cell division also brings the jam session to a close, intricately connecting the two processes. "V(D)J recombination essentially breaks, cuts out and reattaches DNA, so it uses cell's normal DNA repairing machinery...Protein structure initiative advances to rapid production phase
...ch centers, the Protein Structure Initiative (PSI) launches the second phase of its national effort to find the three-dimensional shapes of a wide range of proteins. This structural information will help reveal the roles that proteins play in health and disease and will help point the way to designing new med...Argonne receives $50 million NIH grant
...the announcement, the Protein Structure Initiative launches the second phase of its national effort to find the three-dimensional shapes of a wide range of proteins. This structural information will help reveal the roles that proteins play in health and disease and will help point the way to designing new med...... that connect the brain to the iris of the eye. It launches the neurotransmitter acetylcholine from sac-like vesicles across the synapse to two types of receptors, called alpha 7 and alpha 3. Sejnowski and his colleagues transformed their map into a functional computer model by incorporating the physiological...Corn fungus is nature's master blaster
...a hundred-fold. It also outperforms a rifle, which launches its bullet with less than one-tenth that acceleration. The researchers -- Frances Trail and Iffa Gaffoor of Michigan State University, and Steven Vogel of Duke University -- published their findings in the June 2005 issue of Fungal Genetics and Biolo...Discovery of new dopamine action may yield alternative psychiatric drugs
...s dopamine are chemical messengers that one neuron launches at receptors on another to trigger a nerve impulse in the receiving neuron. Receptors are protein switches on the surfaces of neurons that recognize neurotransmitters and translate their signals into a cellular response. Dopamine exerts its functions...How seizures progress to epilepsy in the young
...mate and GABA are chemical signals that one neuron launches at its neighbor across connections called synapses. Yehezkel Ben-Ari and colleagues decided to explore a possible role of GABA-controlled neural circuitry in seizures in infant animals because it was known that, while GABA excites immature neurons, i...Infectious agent thwarts typical defense mechanisms; Sheds light on immune system function
...nd enters the inside of the cell that the monocyte launches a complete attack. It's only there, inside the mon...ell recognizes Francisella as an intruder and then launches a late assault. "This study is one of the first to show that certain bacteria trigger an immune res...ASU's Nanotech in Society Center hosts launch event
...from across the nation will gather in Tempe as ASU launches its Center for Nanotechnology in Society. The culmination of the launch event will be a Public Forum on Nanotechnology in Society from 4 p.m. to 7 p.m. in the Great Hall (Armstrong Hall) of the College of Law. A distinguished panel of scientists, po...BioMed Central launches Biology Direct
...nal, available online at www.biology-direct.com , launches with publications in the fields of Systems Biology, Computational Biology, and Evolutionary Biology, with an Immunology section to follow soon. Biology Direct considers original research articles, hypotheses, and reviews and will eventually cover the...Two NIH initiatives launch intensive efforts to find roots of common diseases
...pinnings of common illnesses. The other initiative launches a public-private partnership between NIH, the Foundation for the National Institutes of Health (FNIH) and major pharmaceutical and biotechnology companies, especially Pfizer Global Research & Development of New London, Conn.; and Affymetrix Inc. of S...Genomics-based vaccine could prevent deadly cattle disease
... a role in immunity. What's more, because T. parva launches a cancer-like illness inside the white blood cells of cattle, it may provide a model system for understanding the mechanics of cancer biology. But for Nene, who was born in Kenya and worked at ILRI for 15 years before coming to TIGR in 2001, the mar...Engineered mouse mimics cognitive aspects of schizophrenia
...in the brain--a chemical messenger that one neuron launches at its neighbor to trigger a nerve impulse in the receiving neuron. The major antipsychotic drugs are believed to "dial down" the dopamine machinery by blocking receptors for dopamine on the surface of neurons. Also, amphetamines, which release dopam...Broad Foundation donates $25 million to create new stem cell institute at USC
...at this time, as the National Institutes of Health launches an initiative to support clinical and translational research," said Keck School of Medicine Dean Brian E. Henderson. "Our view now is that, in order to solve complex biological problems, scientists must move beyond the confines of their own disciplin...MIT research links cancer, inflammatory disease
...bowel disease, two different camps are at war. TNF launches an attack, killing many of the epithelial surface cells, while EGF struggles to keep the cells alive and dividing to repair the damage. In every cell, genes create proteins, the building blocks of life. Besides carrying out the functions of keeping t...... immune system mistakes "self " for "foreign " and launches an attack. Since DC are central to many immune responses, they are potential targets for the development of new immune therapies. Since their discovery in the US in 1975, it has been known that DC, like other white blood cells, develop from stem cell...