Study begins to reveal clues to the cause and progression of sepsis
...s inflammatory response to an infection, which can lead to organ failure and death. More than 30 percent will die, making sepsis the 10th leading cause of death. While incidence rates of sepsis have been steadily increasing over the years, little is known about the condition. Past investigational treatmen...Multinational research: protecting ecology means understanding people, too
...es in the Amazon. Fitzgerald and Stronza now will lead 20 other professors at Texas A&M University on a $3 million National Science Foundation grant aimed at cutting down barriers between biological and social science in order to help conserve the worlds rich biodiversity. When we were developing this p...Climate change isolates Rocky Mountain butterflies
...s of alpine butterflies from each other, which may lead to the extinction of the colourful insects in some...tire meadow of Parnassius, said Roland, who is the lead author of a paper on this research that appears today in the Proceedings of the National Academy of ...Beyond batteries: Storing power in a sheet of paper
...r, and Saravanababu Murugesan, were co-authors and lead researchers of the project. Other co-authors include research associate Lijie Ci and Rensselaer Nanotechnology Center Laboratory Manager Robert Vajtai. The researchers used ionic liquid, essentially a liquid salt, as the batterys electrolyte. Its im...Unravelling new complexity in the genome
... tissues compared to other mammalian tissues, says lead investigator Professor Benjamin Blencowe of the Banting and Best Department of Medical Research and Centre for Cellular and Biomolecular Research (CCBR) at the University of Toronto According to Blencowe, it is particularly interesting that many o...Diverse genetic abnormalities lead to NF-κB activation in multiple myeloma
Two new studies may lead to the development of more effective therapies for...between them, there are two separate pathways that lead to activation of NF-κB, the classical pathway and the alternative pathway. Constitutive activ...Bursts of waves drive immune system 'soldiers' toward invaders
...also drive cancer cell metastasis, the finding may lead to strategies to block cancer growth. Similarly, faulty regulation of white blood cell movement plays a role in heart attack - another promising target for applying the new insights of the regulation of cell movement, the authors say. White blood ...Protein 'chatter' linked to cancer activation
...u-Dong Zhu, assistant professor of biology and the lead author on the study. As we age, our chromosome ends become shorter. Individuals whose ends deteriorate faster are at a higher risk of developing cancer because short chromosome ends are a serious threat to the stability of our genome. When the genom...Features of replication suggest viruses have common themes, vulnerabilities
...eme that may be vulnerable to disruption and could lead to the development of drugs to treat many different kinds of viral infections, much like antibiotics are used to attack different kinds of bacterial pathogens. "It turns out that viruses previously thought of as distinct share common features," say...Doernbecher Children's Hospital scientist earns coveted Javits award
...diatrics, OHSU School of Medicine."His work should lead to real breakthroughs for patients struggling withthese debilitating disorders. OHSU and Doernbecher are fortunate to havea scientist of his caliber." "The Javits Investigator Award for Dr. Back is a recognition of hisseminal contributions to the f...Gene regulation, not just genes, is what sets humans apart
... Duke biology professor Gregory Wray. Haygood is lead author in a report on the research to be published online on Sunday, Aug. 12, in the research journal Nature Genetics. His group looked at the regulatory sequences immediately adjacent to 6,280 genes on the DNA of chimps, humans and the rhesus m...MIT creates 3-D images of living cell
...taken from multiple directions, said Wonshik Choi, lead author of the paper and a Spectroscopy Laboratory postdoctoral associate. Cells don't absorb much visible light, so the researchers instead created their images by taking advantage of a property known as refractive index. Every material has a well-...Green tea boosts production of detox enzymes, rendering cancerous chemicals harmless
...hemicals and other toxins, according to the studys lead investigator, H.-H. Sherry Chow, Ph.D., a research associate professor at the University of Arizona. They modify the cancer-causing molecules that would otherwise damage cellular DNA, thus rendering them inert. They actually convert known carcino...Does the desire to consume alcohol and tobacco come from our genetic makeup?
...ng. Conclusions According to Mr. Nikpay, the lead author of the research, We have found evidence of linkage and association for several genomic regions harboring genes with potential pathophysiological functions relating to alcohol and smoking. Our sex specific findings may also play a role in the s...High blood pressure, low energy -- a recipe for heart failure
...nges in the ability of the heart to produce energy lead to heart failure in some cases. "ERR and some of its partners in the cell are a little like puppeteers controlling the expression of genes for energy production," Kelly says. "This research is especially exciting because ERR can be activated with sma...X-ray images help explain limits to insect body size
...team focused in particular on the passageways that lead from the body core to the head and to the legs. They reasoned that these orifices may be bottlenecks for tracheal tubes, limiting how much oxygen can be delivered to the extremities. We were surprised to find that the effect is most pronounced in t...Abnormal fat metabolism underlies heart problems in diabetic patients
... the cells, creating unhealthy conditions that can lead to heart problems. Interestingly, a rare genetic disorder Barth syndrome held a key to identifying cardiolipin decrease in diabetic hearts. Children born with Barth syndrome have weak hearts and often die young from heart failure. These children ha...Scientists show that mitochondrial DNA variants are linked to risk factors for type 2 diabetes
...mon genetic diseases, says Dr. Theodore Kurtz, the lead investigator on the project. In addition, the animal models developed in this study will open the door for future studies in which the effects of mitochondrial genome variation can be investigated on fixed nuclear genetic backgrounds. ...Rain forest protection works in Peru
...in Peru happened in natural protected areas, noted lead author Paulo Oliveira. However, there was substant...nced signal processing approach developed by study lead Greg Asner. Our approach has improved over the past eight years, but relies on a core set of meth...... There are various types of glaucoma, all of which lead to damage in the optic nerve and progressive loss of vision. Exfoliation glaucoma is caused by the buildup of fibrous deposits on the surfaces on the front of the eye. Between 10-20% of people over the age of 60 are believed to have some degree of ex...