U-M researchers discover gene switched off in cancer can be turned on
...ted about the potential this finding could have in leading to new targets for cancer treatment. This is a targetable target. We can detect it, but we need to find a better way to turn it back on. No drugs are designed to deal with a gene thats turned off. But its a straightforward extension of current ther...Cell Press announces new partnership with the American Society of Human Genetics
...With an impact factor of 12.65, the journal is the leading publication in the field of human genetics. We are...mmunity and for consistently delivering the worlds leading research across the broad spectrum of life sciences. ASHG will be linked with Cell Press to provide ...Scientists propose the kind of chemistry that led to life
...perate and compete with each other in simple ways, leading to arrangements that can become stable, or locked in, says Ken Dill, PhD, senior author of the paper and professor of pharmaceutical chemistry at UCSF. The scientists compare this chemical process of search, selection, and memory to another well-s...Hormone that signals fullness also curbs fast food consumption and tendency to binge eat
...ar (such as pizza, chocolate and ice cream), often leading to a sense of reward. The pramlintide group reduced fast food intake by 385 calories on day 44 during the fast-food challenge, compared to the placebo group, which decreased their intake by 109 calories. Those taking pramlintide also reduced their sc...University of Manchester researchers reveal clues to new genes behind rheumatoid arthritis
...sful academic collaborations to date, involving 50 leading research groups and over 200 scientists in the field of human genetics from dozens of institutions. For these papers, part of a number of studies due to be published over the next year, the researchers analysed 17,000 DNA samples taken from people in...Columbine flowers develop long nectar spurs in response to pollinators
...tion of the length of nectar spurs--the long tubes leading to plants' nectar--happens in a way that allows flowers to match the tongue lengths of the pollinators that drink their nectar, biologists have found. The researchers were Justen Whittall of the University of California at Davis and Scott Hodges of...QUT microgravity tower attracts global scientific community
...greatly enhanced when it occurs in reduced gravity leading to better materials and that the solidification of metals in reduced-gravity environments produces stronger structures than are formed in normal gravity....Largest ever study of genetics of common diseases published today
... 17,000 people across the UK, bringing together 50 leading research groups and 200 scientists in the field of human genetics from dozens of UK institutions. Over two years, they have analysed almost 10 billion pieces of genetic information. "Many of the most common diseases are very complex, part 'nature' ...Crucial progress in understanding Fragile X mental retardation protein
...le new treatments for Fragile X syndrome(FXS), the leading inherited form of mental retardation. The findin...y a mutation in the FMR1 gene on the X chromosome, leading to the loss of FMRP, which is abundantly expressed in the brain and testes. Without this protein, b...Viable tiger populations, tiger trade incompatible
...the cover story of this months BioScience journal, leading tiger experts warn that if tigers are to survive, governments must stop all trade in tiger products from wild and captive-bred sources, as well as ramp up efforts to conserve the species and their habitats. The paper, The Fate of Wild Tigers, describ...PET/CT: The best test for women with ovarian cancer
...cercancer that forms in tissues of the ovaryis the leading cause of death in women with gynecologic cancer, noted Fulham. In the United States, reports indicate that more than 22,000 new cases and more than 15,000 deaths attributed to ovarian cancer are expected this year. "Unfortunately, while positive resu...Nexavar significantly extends overall survival by 44 percent in liver cancer patients
...fth most common cancer in the world3 and the third leading cause of cancer-related deaths globally.4 Over 600,000 new cases of HCC are diagnosed globally each year4 (19,000 in the United States5 and 32,000 in the European Union6), and in 2002 approximately 600,000 people (about 13,000 Americans and 57,000 E...SNM recognizes R. Edward Coleman with 2007 Georg Charles de Hevesy Nuclear Pioneer Award
...blished more than 400 scientific papers in several leading journals, has authored 80 book chapters and has published seven textbooks on topics related to nuclear medicine. He has been on the editorial boards of several top medical journals including the Journal of Nuclear Medicine, Radiology and Academic Rad...Discovery in orange cauliflower may lead to more nutritious crops
...es, leads to compromised immune systems and is the leading cause of blindness in children. "A large percentage of the human population depends on staple crops for nutrition," said Li, an adjunct assistant professor in the Department of Plant Breeding and Genetics and a scientist at the U.S. Department of Agr...Cold Spring Harbor Protocols features methods to understand embryos, clones, stem cells
...velopment, cellular reprogramming, and even events leading to cancer and other disease states. One of the protocols, freely available at http://www.cshprotocols.org/cgi/content/full/2007/12/pdb.prot4767 , describes how to characterize these epigenetic marks in native chromatin (i.e., the DNA is still bou...2nd International EuroFIR Congress
...ean Food Information Resource Network) , the world leading European Network of Excellence on Food Composition Databank systems, is a partnership between 46 universities, research institutes and small-to-medium sized enterprises (SMEs) from 25 European countries. EuroFIR will provide the first comprehensive p...When the villain becomes your friend: The strange tale of muscle lactate
...f Aarhus in Denmark, add to the growing literature leading to a more complete understanding of the physiological role of lactic acid production in muscle. In the late 19th century, fermentation chemists realized that juice left to ferment without adequate oxygen resulted in acid products. Then, in the ear...Scientists honored with 'Excellence in Clinical Research Award'
...f growth factor peptides to regenerate islet cells leading to the development of and clinical trials for new compounds to induce beta cell regeneration. A JDRF-funded researcher for many years, Dr. Rabinovitch has received many awards and served on many professional committees and offices, including, since 2...Researchers discover inherited mutation for leukemia
...e occurs later that turns the gene off altogether, leading to leukemia. This latter alteration is a chemical change that is not inherited. The findings could help identify people at risk for chronic leukemia, but they also may provide new insights into the process of natural cell death. They may even lead...Existence of muscle-building stem cells points to regenerative therapies for muscular disease
...rugs that specifically target the relevant pathway leading to satellite stem cell expansion."...