How E. coli evolves to adapt to changing acidity
...gy, a fascinating new selection of papers collects leading experimental research in evolution and artificial selection, providing insight into how organisms adapt to changing environmental conditions and fluctuations. Dr. James Hicks, Editor in Chief of PBZ, explains the momentum behind this collection of...Yin and yang -- Balance could play key role in progression of Alzheimer's disease
...in the brain and the persons memories become hazy, leading to eventual dementia." Wang expects that this imbalance could be the main factor in the progression of Alzheimers disease. If correct, the addition of AB40 may stop the diseases development. Wang notes that further research is needed, but his prel...Ants show us how to make super-highways
...nts use their bodies to plug potholes in the trail leading back to the nest, making a flatter surface so that prey can be delivered to the developing young at maximum speed. The raid always remains connected to the nest by a trail of forager traffic, along which prey-laden foragers run back to run back to ...Genome of Clostridium botulinum reveals the background to world's deadliest toxin
...ving animal, via contaminated food or open wounds, leading to infant botulism or wound botulism, both of which are serious human infections. The host can be quickly overpowered and, in some cases, killed by the toxin, and C. botulinum has a new food source. "Although in the same group as Clostridium diffi...Fire ants are emerging nuisance for Virginians
...culture crop insects and entomology professor, are leading Extensions efforts to research RIFAs and educate Virginians about this issue. The Virginia Department of Agriculture and Consumer Services (VDACS) currently manages and treats all fire ant infestations in the commonwealth. Most homeowners and land...New mouse model closely mimics human cancers
...ncer cells exhibited "rampant genome instability" leading to a complex pattern of mutations, chromosomal rearrangements, gene amplifications and gene deletions similar to those in human solid tumors. The mouse model's close resemblance to human T-ALL enabled the scientists to rapidly and efficiently ide...Story ideas from the Journal of Biological Chemistry
...e death of neurons that control voluntary muscles, leading to muscle weakness and atrophy. Around 25 percent of the familial forms of the disease forms that occurs repeatedly in family members but is not necessarily inherited have been linked to mutation in a gene that makes a protein called superoxide dis...New genetic data overturn long-held theory of limb development
...ition for the fin in any vertebrate, and the group leading to tetrapods elaborated on this Hox expression by adding a second phase and added to the skeletal pattern. The scientists studied the development of paddlefish fins to test whether the genes activated to make hands and feet in tetrapods were differen...Botulism bug has few genome wrinkles
...ving animal, via contaminated food or open wounds, leading to infant botulism or wound botulism, both of which are serious human infections. The host can be quickly overpowered and, in some cases, killed by the toxin, and C. botulinum has a new food source. "Although in the same group as Clostridium diffi...Flaws in colonoscopies may increase risk of colon cancer
...ld standard for detecting colon cancer, the second leading cause of cancer deaths in the United States. Rese... to 20.7 percent in those over the age of 75. The leading reason for unsuccessful examinations was poor preparation (42.5%). Contrary to popular belief, just...News tips from the Journal of Neuroscience
...ll as dynein staining that was concentrated at the leading edge. Dynactin and LIS1 were colocalized with dynein. A similar staining pattern was observed in growth cones of rat hippocampal neurons. Knockdown of LIS1 by RNA interference delayed polarization of hippocampal neurons and decreased axonal lengths. ...UVa researcher studying disease that cripples newborns
...oundbreaking ResearchDr. Mahadevan has been on the leading edge of DM research for more than a decade. In 1992, as a member of a Canadian research group, he helped discover the genetic mutation that causes DM1. The mutation occurs when a gene called myotonic dystrophy protein kinase (DMPK) makes extra cop...Study focuses on only carnivore with 'fingerprints'
...ey. They are also spreading westward, with today's leading edge around Syracuse. Fishers were first recorded in the suburbs of Albany and Boston in the last six years....Immune antibodies penetrate neurons to clear Alzheimer's-linked amyloid
...brain," Dr. Gouras explains. He remains one of the leading authorities on beta-amyloid plaques because of earlier work on its deposition and accumulation between neurons. "One of the things those earlier immunotherapy studies taught us was that antibodies can reduce amyloid plaques, which are a hallmark of...How does day length affect aggression in mice? It's in the genes
...h these specific genes, creating a genomic pathway leading to less aggressive behaviors, Trainor said. The flip side of this finding is that estrogen increases aggression in short-day mice through different cellular mechanisms not involving genomic pathways. While it would be difficult to test that hyp...Weill Cornell pharmacologist receives prestigious NIH MERIT Award
...tions of diabetes NEW YORK (May 21, 2007) -- A leading authority and pioneer in the pharmacology of the signaling molecule nitric oxide (NO), Weill Cornell Medical College scientist Dr. Steven S. Gross has been selected by the National Heart, Lung, and Blood Institute (NHLBI) to receive a 2007 National I...New techniques redefine assessment of liver disease
...ads to abnormal blood glucose levels and diabetes, leading researchers to the conclusion that "prognostic biomarkers" can be developed that can potentially predict resolution of important complications of obesity such as DM. "Recognition of specific cell signaling pathways using Reverse Phase Protein Micro...Jackson Laboratory researcher receives JDRF's Grodsky award
...ork from my laboratory may play some small part in leading to cures for type 1 diabetes." Dr. Serreze has been with the Jackson Laboratory since 1991. He is also adjunct research professor of medicine at the University of Massachusetts Medical Center, Worcester. A two-time recipient of JDRFs Mary Jane Kuga...Ocean observing contracts awarded to UC San Diego and University of Washington
... Oceanographic Institutions (JOI), a consortium of leading U.S. oceanographic research institutions, has awar...of Washington was awarded the opportunity to begin leading one of the complex parts of the Ocean Observatories Initiative (OOI), to construct a cabled underwat......ars by OSU's Linus Pauling Institute, and attracts leading experts from around the world in these research fields. ...