Tag: "lesions" at biology news
Other highlights in the August 3 JNCI
...DCs appear to have a role in the responsiveness of lesions
to imiquimod treatment. Contact: Mirjana Urosevic ( Mirjana.Urosevic@usz.ch ) or Reinhard Dummer ( Reinhard.Dummer@usz.ch ), University Hospital Zurich Also in the August 3 JNCI: Study Evaluates Averted Costs of Neuroblastoma Screening Few Benef...
$3.4 million directed to key UW-Madison MS study
...e used in transplants to repair the nervous system lesions
characteristic of multiple sclerosis. The project,...) and Positron Emission Tomography (PET), to image lesions
and how they respond to treatment. The work to be funded by the new grant, part of a five-year, $30 ...
Brain tumors may originate with neural stem cells, researchers say
.... Strategies that focus only on treating localized lesions
would not be sufficient to eradicate tumor cells because these cells may eventually be replenished from the cell pool within the subventricular zone, the researchers said. They also determined that inactivation of both p53 and NF1 is sufficient to in...
Scientists find cell surface enzyme matriptase causes cancer
...ch matriptase developed distinctive, splotchy skin lesions
within a year." According to Szabo, that's when t...expected turn. He and his colleagues biopsied the lesions
and, to their surprise, found that they were tumors that had already advanced in most cases to a typ...
Failure to dispose of unneeded cells during development linked to cancer
...Hospital and colleagues found that all the genetic lesions
associated with inherited pheochromocytomas result in a reduction of programmed cell death, called apoptosis, during development. The researchers show that mutations in each of the disparate genes that cause familial pheochromocytoma, NF1, c-RET, SDH...
Tissue engineered from fetal skin cells could treat paediatric burns
...laced fetal skin cell constructs on the children's lesions
and bandaged them. They changed their dressings every 3-4 days for 3 weeks. The researchers found that all the children had their wounds closed at just over 2 weeks and no child needed traditional grafting because the fetal constructs closed their wo...
JCI table of contents September 1, 2005
...ly, but non-invasively, visualize the inflammatory lesions
in the pancreas that cause the disease. In a study appearing online on August 18 in advance of print publication of the September 1 issue of the Journal of Clinical Investigation , Diane Mathis and colleagues from Joslin diabetes Center describe a...
Looking at autoimmune diabetes, literally
...ly, but non-invasively, visualize the inflammatory lesions
in the pancreas that cause the disease. In a study appearing online on August 18 in advance of print publication of the September 1 issue of the Journal of Clinical Investigation, Diane Mathis and colleagues from Joslin diabetes Center describe a n...
New gene associated with Fanconi anemia 'explains' hallmark chromosomal instability
... now suggest that DNA double-strand breaks are the lesions
that underlie the pathology of this disease," says Auerbach, who is internationally known for her work on the disorder and for the large Fanconi anemia registry she maintains at Rockefeller. Fanconi anemia (FA) is an inherited disorder characterized...
Tobacco-related cancer: How does it happen?
...pounds polycyclic aromatic hydrocarbons may form lesions
in DNA, which can lead to gene mutations that allow cancer cells to emerge and grow unchecked. ( TOXI 30 , Tuesday, Aug. 30, 8:00 a.m.) Epidemiology of tobacco-related cancer Scientists estimate that only 25 percent of smokers develop lung cancer...
Prostate cancer uses Wnt signaling proteins to promote growth of bone tumors
...ekeeping in bone tissue and produce the dense bony lesions
characteristic of prostate cancer. Now, new research by scientists at the University of Michigan's Comprehensive Cancer Center suggests that prostate cancer manipulates an important group of signaling proteins called Wnts (pronounced "wints") to esta...
Dye imaging ID's oral lesions likely to become cancer
...ue of "Cancer Research", the scientists found that lesions
that took up the dye known as toluidine blue were ...s. The team also discovered that the dye-staining lesions
contained molecular alterations that are linked to high risk of oral cancers -- even at early stages...
What causes psoriasis?
...by inflamed, scaly and frequently disfiguring skin lesions
and often accompanied by arthritis of the small jo...l alterations are sufficient to initiate both skin lesions
and arthritis in psoriasis. Or, as Nature puts it, "outside-in" rather than "inside-out"....
Other highlights in the September 21 JNCI
...ssue from 10 sporadic cutaneous malignant melanoma lesions
for expression of RASEF, a known gene in this region. Expression was found to be decreased in 70% of these tumors compared with RASEF expression in a human reference RNA pool and in 10 breast cancer tumors. The authors conclude that a novel susceptib...
Study demonstrates how gene variant may contribute to cancer development
...ne appears to be frequently acquired in metastatic lesions
from colorectal cancer, and give cancer cells a growth advantage, according to a study in the October 5 issue of JAMA. Transforming growth factor beta (TGF-beta) is a potent naturally occurring inhibitor of cell growth, according to background inform...
NHGRI's large-scale sequencing research network sets its sights on disease targets
...parasitic disease responsible for disfiguring skin lesions
and damage to the spleen, liver and bone marrow. I...loyed during the Gulf War have contracted the skin lesions
caused by leishmaniasis. Sequencing the genomes of the sandflies will give researchers a better unde...
JCI table of contents November, 2005
... block the action of BLyS and APRIL in the disease lesions
the authors treated human synovium-SCID mouse chimeras with the decoy receptor TACI:Fc. Treatment destroyed germinal centers, blocked immunoglobulin production and inhibited expression of the T cell cytokine IFN-_. Surprisingly, inhibition of BLyS an...
Lippman recognized for discoveries in cancer prevention
...ognosis for patients at high risk for premalignant lesions
can be similar to or even bleaker than that of some early-stage cancer sufferers, and therapeutic drugs can have molecular targets in both premalignancy and malignancy. His laboratory group discovered a pathway that signals apoptosis (programmed cel...
New ECCO 13 data emphasise vital importance of cervical cancer detection, treatment and prevention
...fection. Using CIN 2/3 and AIS obligate precursor lesions
for cervical squamous cell and adeno-carcinoma res...ion of HPV 16/18-related CIN 2/3 and AIS precursor lesions
and consequent risk of cervical cancer. Dr Kevin Ault from the Emory University Hospital, USA report...
Making medicine 'smarter'
... to the improved diagnosis of indeterminate breast lesions
by non-invasive imaging," Meyer-Baese said. "We will deliver a flexible and reusable software system in MR mammography." Meyer-Baese said she was "thrilled" to hear that she had been chosen for an NIH Career Award. "I was very excited, because I can ...
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