Tag: "lesions" at biology news

Full year of treatment helps infants and children with toxoplasmosis

...function, vision, including the development of new lesions in the eye, and hearing loss. The authors emphasiz...ment of vision, 64 percent have had no new retinal lesions since beginning treatment. Unfortunately 11 of the 96 severely affected infants died, nine of them f...

'Pinball protons' created by ultraviolet rays and other causes can lead to DNA damage

...nisms as radiation or chemical exposure, can cause lesions in DNA. The work was done entirely on computers in...e-Cytosine (G-C) base pair is involved in creating lesions that can lead to replication errors. This pair has 10 protons, meaning there are numerous targets fo...

Jefferson scientists identify gene mutation potentially involved in breast cancer initiation

...for some reason rises dramatically in premalignant lesions and cancer. Dr. Lisanti's team developed mice lacking the Caveolin-1 gene and found a dramatic increase in both number and activity of estrogen-positive receptors in mouse breast tissue, specifically in breast epithelial cells, in turn, promoting cel...

Just-right PET/CT imaging for patients of all sizes

...ng reproducible phantoms mimicking the presence of lesions in a patient," said Surti. New time-of-flight measurement capability--when used in reconstructing an image--improved image characteristics, which in turn allowed more accurate detection of small lesions, some of which are not visible in a conventiona...

A step toward halting Alzheimer's: Using FDDNP PET to detect disease progression, MCI

... to detect and measure the levels of both types of lesions in the brains of living Alzheimer's patients using...successfully used for imaging of neuropathological lesions in Alzheimer's disease patients with PET," noted Kepe. Combined with the results of PET studies usin...

HPV testing finds precancerous lesions at a higher rate than conventional pap smears

...n traditional Pap smears at detecting precancerous lesions of the cervix, a study in the June 7 issue of the Journal of the National Cancer Institute reports. A new, liquid-based form of the Pap test marginally improved sensitivity but also produced more false positives. Previous studies have shown that se...

Novel non-invasive imaging technology may allow precise diagnosis of coronary artery disease

...assessing the physiologic significance of coronary lesions in patients with chest pain, said Keidar. Computed tomography coronary angiography (CTCA)--an emerging technique for non-invasive detection of the narrowing of a blood vessel (coronary stenosis)--is an X-ray-based exam of the blood vessels or chamber...

The cytokine diet: The next fad in weight loss?

...mon mouse model for obesity that involves inducing lesions in the hypothalamus--a part of the brain that regu...n MSG. Interestingly, these mice neither developed lesions nor did they gain weight. According to doctoral student Laurence Macia and co-authors, the results i...

Speeding discovery of the 'human cancer genome'

...es have been linked to liver cancer, "how specific lesions interact to produce its aggressive characteristics remains poorly understood." Lowe's team relied on mice with specific pathological changes known to play a role in some liver cancers. They then searched for other spontaneous mutations in the anima...

New clues for treatment of liver cancer

...s, two of which were designed to mimic the genetic lesions that are known to occur in human liver and other cancers (namely, deletion of the p53 gene and activation of the Myc gene). A third genetic modification (the insertion of a gene that encodes a fluorescent marker protein) enabled the researchers to vi...

Potato blight pathogenicity explained by genome plasticity

... today. Infected plants are characterized by dark lesions on the stems, leaves, and tubers; damage to the tuber surface allows other fungi and bacteria to enter and destroy the core, often resulting in a foul odor. P. infestans is related to approximately 65 other pathogens that cause similar damage to c...

Cell survival depends on chromosome integrity

...ns. If the DNA repair machinery does not fix these lesions to maintain chromosome integrity, the cell would lose control of growth or death. Moving forward, the team hopes to further understand what controls these sirtuins to remove acetyl groups and how hyperacetylation can lead to such dramatic loss of ...

Higher risk for cervical cancer seen among women infected with multiple HPV types

...ultiple infections are at higher risk for cervical lesions than those ever infected with one type only and sh...icularly prone to increase risk" for pre-cancerous lesions in the cervix, said Helen Trottier, Ph.D., the first author of the research paper. Participating ...

Coming soon: 3-D imaging that flies 'through' and 'around' cancer

...T scan. Even so, with 3-D CT scans, small and flat lesions in the lungs and colon are difficult to see or characterize, said Quon. "Our study takes this to another level," he noted, indicating that fused PET/CT images with 3-D volume rendering may provide additional beneficial information for image interpret...

Beyond lipids: understanding the mechanics of atherosclerosis

...essel cells that could explain why atherosclerotic lesions form preferentially at branches of coronary arteri...t. "We've known for decades that atherosclerotic lesions develop preferentially at vessel branches rather than along unbranched vessels, but we've not been a...

Natural vitamin E tocotrienol reaches blood at protective levels

...d, which in excess can cause vascular and neuronal lesions associated with cardiovascular disease, and the fatty acid linoleic acid, which can directly stimulate damaging free radical activity. Fatty acids are related to stroke: They rapidly accumulate when a clot in a vessel stops blood flow to the brain, a...

Pollution threatens coral health by preventing lesions from healing, UCF study shows

...ked how quickly coral regenerated lost tissue from lesions they created while collecting samples. Scientists have long been concerned about declining coral reef health off the southeastern Florida coast, in the Florida Keys and worldwide. The World Research Institute's Reefs at Risk program has listed coas...

Dietary modifications may not benefit cancer patients

...nts delays the progression of precancerous gastric lesions to cancer. Numerous studies have linked dietary...ents did not reduce the prevalence of precancerous lesions or gastric cancer, but treatment to kill Helicobacter pylori may limit the progression of these ...

Links between DNA damage and breast cancer studied

...elated concentrations of two similar mutagenic DNA lesions and again demonstrated that their occurrence is ro...ing breast cancer risk." The findings suggest that lesions measured in the DNA of the stroma, which is readily obtained, may prove to be convenient and sensiti...

First human study confirms that immune cells can be a primary cause of bone loss in gum disease

...he cellular source of RANKL in the bone resorptive lesions of periodontal disease. An active periodontal lesion is characterized by the prominent infiltration of B cells and T cells, both of which are major immune lymphocytes. Specifically, the occupancy of 50-60% of such cellular infiltrates by plasma cell...

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(Date:10/31/2014)... steps involved in programmed cell death, offering new targets ... neurodegenerative diseases. , The research teams from the ... the three-dimensional structure of a key cell death protein ... it causes cell death. Their studies were published in ... Proceedings of the National Academy of Sciences . ...
(Date:10/31/2014)...  HITLAB SM , a healthcare innovation and ... HITLAB Innovators Summit SM on December 1, ... partner with the Clinton Foundation,s Health Matters Initiative, ... Business School Alumni Club of New ... Operations Research, bringing together leaders in healthcare and ...
(Date:10/30/2014)... EAST LANSING, Mich. – When most animals begin life, ... tail or a vital organ. However, mammals, including humans, ... make a different first choice – to become the ... , It,s during this critical first step that research ... results, published in the current issue of ...
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