Tag: "lesions" at biology news

Major gene study uncovers secrets of leukemia

...nificantly speed the identification of the genetic lesions that are the underlying cause of not only ALL, but also many other cancers, including those affecting adults," said James Downing, M.D., scientific director and chair of the Pathology department at St. Jude. He is senior author of the paper. The s...

Could estriol be the elixir for MS?

...kable" results an 80 percent drop in inflammatory lesions in the brain, a hallmark of the disease. This month, Voskuhl begins a much larger trial of estriol, one that will involve 150 patients at multiple locations over the next two years. The prospects, she said, are exciting. Multiple sclerosis is an...

AACR establishes new lecture in honor of Princess Takamatsu

...'s original research seeking to define the genetic lesions in retinoblastoma provided the first genetic evidence for the existence of tumor suppressor genes, one of the most influential breakthroughs in cancer research. This breakthrough confirmed the "two-hit hypothesis," fundamentally altering the way sci...

AACR Annual Meeting showcases significant developments in understanding and targeting cancers

...6/18 LI VLP AS04 candidate vaccine on precancerous lesions and the human papillomavirus Studies demonstrating the protective effects of certain vegetables, fruits and tea against ovarian, pancreatic and breast cancers Late-breaking findings from studies of cetuximab in people with chemotherapy-refractory co...

Other highlights from the April 18 Journal of the National Cancer Institute

...r-forming epithelial cells from their primary DCIS lesions to allow a better understanding of their growth," the authors write. Contact: Gillian Farnie, Ph.D, of the University of Manchester, 0161 446 3212, Gillian.Farnie@manchester.ac.uk Shortened HER2 Gene Responds to Lapatinib, Not Trastuzuma...

Omega-3 fatty acid may help prevent Alzheimer's brain lesions

...mega-3 fatty acid may slow the growth of two brain lesions that are hallmarks of Alzheimers disease, UC Irvin...ngles. Such tangles are one of two signature brain lesions of Alzheimers disease. DHA also was found to reduce levels of the protein beta amyloid, which can cl...

Study links faulty DNA repair to Huntington's disease onset

...eathe. DNA repair enzymes initially keep oxidative lesions in check, but over time, increasing numbers of lesions overwhelm the repair systems. Oxidative lesions also accumulate in people who do not have Huntington...

Stretching DNA to the limit

...leotide chains, as well as causes the formation of lesions by linking together the adjacent strands. The small changes in structure induced by this crosslinking can very profoundly affect the ability of DNA to recognize specific molecules, and can thus completely disrupt its ability to replicate and interact...

News tips from the Journal of Neuroscience

...tions and produce CPSP. Although all subjects had lesions to the Vc, the VMpo remained intact. Nevertheless, sensitivity to cold and tactile pain was compromised in each case. Unlike other subjects, the patient with the best-preserved Vc had a normal threshold for cold sensation. Heat pain thresholds were u...

May: Multiple Sclerosis Awareness Month -- latest research is good news

...imab significantly reduced the number of new brain lesions and the frequency of relapses, times when symptoms...latively mild side effects. In addition, new brain lesions appeared reduced by more than 90 percent with a decrease in the frequency of relapses. Similar resul...

Healthy reefs hit hardest by warmer temperatures

...s via tentacles and digestive filaments that cause lesions and tissue damage, providing an inroad for infection. Close quarters among coral colonies could also make it easier to spread disease. The research was funded in part by grants from the National Science Foundation; an Environmental Protection Agenc...

Testosterone may help men with multiple sclerosis

...rkable results an 80 percent drop in inflammatory lesions in the brain, a hallmark of the disease. That led to a much larger trial now underway. Her goal now is to expand this testosterone pilot study into a much larger clinical trial. "Overall, the use of the testosterone gel treatment in men with MS wa...

Dinosaur hearing, listening to muscle noise, quieter cubicles

...e imaging technique using ultrasound to search for lesions in breast tissue. Generally the rival approaches ... Mammography (using x rays) has trouble detecting lesions in dense breasts often seen in young women. Conventional ultrasound can spot lesions but cannot mea...

Cytomegalovirus exacerbates atherosclerosis through an autoimmune mechanism

...fection can be responsible of the initial vascular lesions typical of the atherosclerotic process. The mechanism involved in the vascular lesion is of autoimmune origin: antibodies directed against particular proteins of the virus are able to bind molecules expressed on the surface of the cells that line the...

News tips from the Journal of Neuroscience

...half of the grafted and nongrafted rats had second lesions to DA projections originating outside the substantia nigra pars compacta. The second lesion obliterated improvements gained from grafting. The authors propose that patients who fail to benefit from striatal grafts may have damage to ventral striatum ...

JCI table of contents -- June 1, 2007

...ng thrombin, exacerbates the formation of arterial lesions following arterial injury or in response to abnormally elevated levels of lipids in the blood in mice. They suggest that this possibly occurs through excessive thrombin signaling through protease-activated receptors. They go on to show that these sym...

CSIRO scientists join fight to save 'Tassie devil'

...ate AAHL scientists have processed and examined 29 lesions from 12 affected animals and have also collected and processed a further 30 affected animals where both tumour tissue and tumours grown in the laboratory were examined. A recent Senior Scientists Scientific Forum on the DFTD reviewed progress in u...

PET/CT should be 'first-step' test for patients with Crohn's disease

...udy, all bowel areas that showed severe endoscopic lesions were correctly identified by PET/CT. There was not...le case in which the ileocolonoscopy showed severe lesions and PET/CT showed a normal metabolic activity," said Hustinx. "Conversely, this means that when the ...

What's going on in the body? Advanced time-of-flight PET takes a superior 'look'

...ncer," she added. "In some cases, TOF/PET detected lesions that are missed with conventional PET," said Perkins. ...

Evolutionary relevance of retinoic acid-induced craniofacial malformations

... to the developing foetus. How these developmental lesions are generated remains, however, enigmatic since neural crest cells, which generate most craniofacial structures, do not respond to RA. The authors perform a detailed anatomical analysis of the craniofacial defects induced by treating mouse embryos...

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