Encouraging results of gene therapy for severe combined immunodeficiency
...entified from bone-marrow cells and spliced into a leukaemia virus. This virus was then introduced back into the patients where the gene was replicated. Almost normal immune functioning became established in all 4 patients after the procedure. Lead investigator Adrian Thrasher (Institute of Child Health, Londo...Essential oils could help to stamp out MRSA
...nt being at risk," added Jacqui. Jacqui works with leukaemia patients at the Christie Hospital using essential ...ment. Patients receiving treatment for cancer and leukaemia are often left with weakened immune systems which makes them vulnerable to infection from MRSA.The N...Cell research signals cancer hope
...own as 'Notch', which has been linked to a form of leukaemia called T-ALL. The Notch receptor, of which there are four types in humans, is unusual in that once it has picked up a signal, it splits into two and part of it actually becomes the signal on its journey to the cell nucleus. What Dr Baron has discover...Chernobyl: The true scale of the accident
...ntains both the known radiation-induced cancer and leukaemia deaths and a statistical prediction, based on estimates of the radiation doses received by these populations. As about quarter of people die from spontaneous cancer not caused by Chernobyl radiation, the radiation-induced increase of only about 3% wi...New test proves effective in more cancers
...uppressor gene associated with acute lymphoblastic leukaemia (ALL) in children. By using a simple test developed at the Institute, they can rapidly detect the presence or absence of these tumor suppressor genes in the patient's cancer cells. Tumor suppressor genes are linked to a variety of cancers including ...JCI table of contents November, 2005
...atological malignancy. TITLE: NKT cell-dependent leukaemia eradication following stem cell mobilization with potent G-CSF analogues AUTHOR CONTACT: Edward Morris Queensland Institute of Medical Research, Brisbane, Australia Phone: 61 7 3845 3773; Fax: 61 7 3845 3509; E-mail: edwardM@qimr.edu.au View th...Pillows - a hot bed of fungal spores
...as become the leading infectious cause of death in leukaemia and bone marrow transplant patients. Fungi also exacerbate asthma in adults. The researchers dissected both feather and synthetic samples and identified several thousand spores of fungus per gram of used pillow - more than a million spores per pillow...Cosmopolitan lifestyle could allay cancer threat
...pound inhibits the growth of human lung, colon and leukaemia cells in culture, but does not affect healthy cells. These findings are published in the Journal of the Science of Food and Agriculture1. Navindra Seeram, UCLA Centre for Human Nutrition, says that the effect of this compound is new finding, and th...Genome discovery will help combat disease and lead to new drugs
... which includes both the leading cause of death in leukaemia and bone marrow transplant patients and an essenti...he leading infectious cause of death in vulnerable leukaemia and bone marrow transplant patients. Aspergillus nidulans has been a leading experimental system he......a month or more,' he says. Moreover, children with leukaemia have a weakened immune system. If a germ enters their bloodstream via a wound, the result may be a fatal case of blood poisoning. For several years now Bonn paediatricians have been pioneering the use in Germany of medihoney in treating wounds. Medi...Thrombosis in children with leukaemia
...versity of L'Aquila. Thrombosis in children with leukaemia is a serious problem, that adds a new clinical concern for these children already troubled by such a severe disease.Prevention and focused therapy are essential in order to avoid complications that may turn out to be extremely harsh. What is the freq...18th EORTC -- NCI -- AACR Symposium
...inevitable after treatment for acute lymphoblastic leukaemia now new therapies can be designed to target these cells Diptheria toxin used in new immunotherapy against melanoma in humans; promising results from phase II trial Scientists design a PSA-activated drug that kills prostate cancer. It has poten...Deakin University discovery could lead to new leukaemia treatments
...dentified a protein that could hold the key to new leukaemia treatments. The protein--Stat5--was investigated...identify Stat5 as a major player in the process of leukaemia progression and is therefore a worthwhile target for intervention." Associate Professor Ward said ...Researchers identify cells that make relapse inevitable in acute lymphoblastic leukemia
...tralia have discovered that in acute lymphoblastic leukaemia (ALL) there are Dr Jekyll and Mr Hyde cells "good...erprint' each lymphocyte in order to know what the leukaemia 'looks' like. We found 'fingerprints', or clonal markers, that revealed the emergence or evolution ...Chemotherapy can be more toxic to brain cells than to cancer cells and may cause brain damage
... interferes with cell metabolism, is used to treat leukaemia and lymphomas. Dietrich et al.s results show that clinical concentrations of cisplatin, carmustine and cytarabine are more toxic to human neural cells than to cancer cells. The drugs are toxic to both the dividing neural stem cells and the non-div......cacy of gene therapy in treating chronic lymphatic leukaemia and haemophilia B. But successes in clinical testing come with their share of setbacks, such as the currently slight margin of therapeutic effectiveness over unwanted side effects. This underscores the necessity to carefully assess risks and benefits...Epigenetic studies will provide a better understanding of disease
...l agents are now being used to treat some types of leukaemia and breast cancer. The speakers invited to this conference include: Genevieve Almouzni, Institute Curie-Recherche (France); Robin Allshire, Wellcome Trust Centre for Cell Biology (UK) Miguel Beato, Centre de Regulaci Genmica (Spain); Peter Becker, ...