DNA sequence controls expression of gene involved in cancer
...ptionally and posttranscriptionally. One way bcl-2 levels are controlled is through an adenine and uracil-rich sequence of nucleotides in the 3' untranslated region of the bcl-2 mRNA. This sequence, called the AU-rich element, or ARE, recruits a number of proteins that destabilize the bcl-2 mRNA, resulting ...US researchers show cottonseed drug is cancer treatment booster
...nce to drug and radiation treatment caused by high levels of Bcl-2/xL. Gossypol was researched as a male contraceptive in China as long ago as 1929 although the results were not published until 1957, but after large scale studies in the 1970s it was abandoned because some men remained infertile after stoppi...National Science Foundation awards $2 million grant to UC Riverside
... of wildfires. "Nitrogen deposition occurs at high levels in southern California, and is fertilizing our wil...ine the amount of N required to build up different levels of invasive grass fuel, impacting fire frequency. The threshold at which N affects different vegetat...A treatment, not a cure: Calcium silicate neutralizes an acidic stream
...g have documented that Hubbard Brook receives high levels of acid precipitation from emissions largely originating at Midwestern utility plants, as a result many streams on the site are acidic." Likens comments. Adding that, "The only way to successfully combat stream acidity is through improved air quality...Fungus knocks a frog down but not out, raising questions about amphibian declines
.... "Because Litoria lesueuri populations carry high levels of infection of this fungus and the frogs show no sign of distress, this species may very well be a reservoir for the fungus." ...Daphne Koller named MacArthur Fellow
...les questions of how complex information with high levels of uncertainty can be approached using algorithms, probabilistic modeling and other computational methods. These tools strive to represent knowledge and reasoning at the intersection of traditional logic and subjective judgment, and have far-reaching...New biosensor rapidly detects deadly foodborne pathogen
... The ability to detect L. monocytogenes at low levels is essential because most of the foods susceptible...cts, so we need to be able to detect extremely low levels of contamination." Detection at low levels also is important for another reason, Bhun...September/October 2004 Annals of Family Medicine tip sheet
...r clusters of diagnoses are likely to produce high levels of false-positive signals. The Spirituality Index of Well-Being: A New Instrument for Health-Related Quality-of-Life Research By Timothy P. Daaleman, D.O., et al Researchers determined that the Spirituality Index of Well Being, an instrument use...Low dose radiation evades cancer cells' protective 'radar'
...e cancer cells lines were treated with either high levels of radiation or small amounts spread over many days. Low-level radiation is approximately 10 times more powerful than normal exposure, while high doses are 1,000 times stronger. Approximately 35 percent of colon cancer cells survived low-dose radiati...Is Interleukin-6 the 'holy grail' of exercise mediation?
...itional IL-6 research Over the years, "increased levels of IL-6 after exercise is remarkably consistent," ...nd in the treatment of disease." For instance high levels of IL-6 have been found in patients with "metabolic syndrome," which may be explained by the fact th...New study will tackle three major killer diseases
...of the arteries. Their blood sugar and cholesterol levels will be assessed and a number of other risk factors measured. Each participant in the study will also complete a questionnaire covering family medical history, dietary habits, physical activity and health habits including smoking....Viruses found in untreated city water
...r flow in La Crosse that some city wells have high levels of Mississippi River infiltration, other wells have intermediate levels and the remaining wells have little river water in them," Hunt said. "We also know that the Mississi...New genetic tools provide clues to the effects of exercise and diet on obesity, diabetes
...e propose that training coordinately increases the levels of aspartate aminotransferase 1, lactate dehydrogenase B and pyruvate dehydrogenase alpha 1 subunit, increasing glucose metabolism in muscle by liberating pyruvate for oxidative metabolism and therefore limiting lactate efflux," Hittel said. These bi...Interactive health information system to detect Japanese encephalitis in Asia
...the information to be immediately available to all levels of the health system," said Dr. Julie Jacobson, PATH's Director of the Japanese Encephalitis Project. "Surveillance will be made easier by using Voxiva's system to share data. Control of the disease can be improved by getting information to health w...Bugs in the gut could play key role in understanding human disease and drug toxicity
.... The microbes can influence things such as the pH levels in the gut and the immune response, all of which can have effects on the effectiveness of drugs." The researchers believe it will be possible to develop a model for testing the body's response to disease, looking at how the microbes in the gut intera...ASPB opposes ban of GE crops in Butte County Ballot Measure D
...formula and other soy food products. Much lower levels of aflatoxin, a known potential cancer-causing age...engineered rice, known as Golden Rice, with higher levels of beta carotene will address Vitamin A deficiencies in the diets of people in much of the developin...Society for Psychophysiology Research
...n the memory task was associated with below normal levels of activity in areas of the brain involved with paying attention and manipulating information in short-term memory. These findings document the detrimental effects of cocaine use on cognitive function and clarify the mechanism by which cocaine adver...Protein protecting brain from toxins also blocks some chemotherapy from reaching tumors
...nd it protects brain cells from accumulating toxic levels of topotecan molecules that do escape the bloodstr... Mrp4, the drug accumulated to greater than normal levels in the brain tissue and the fluid that surrounds the brain--the cerebrospinal fluid (CSF). The findi...FSU scientist links iron imbalance to Parkinson's disease
... 1 million Americans each year. But excessive iron levels are worse -- much worse. The findings from a st...Mice were fed varying amounts of iron to determine levels that precipitated onset or hastened the progression of Parkinson's-like symptoms such as tremors and......rine mammals might commonly carry "supersaturated" levels of nitrogen, in which a higher-than-normal amount ...d a series of experiments that suggest even modest levels of underwater sound could trigger bubble formation in a liquid of supersaturated nitrogen. The supe...