Promising new research on hereditary diseases
...s in the development of new stem cell lines. These lines of neurons - or brain cells - could also benefit patients and could potentially be used as a reliable and renewable source of tissue for cell replacement therapy. Interesting and promising pilot research findings were presented using high dose crea...UCI scientists first to predict air quality impact of small-scale power sources
...ses, reduces the need for unsightly overhead power lines and facilitates the use of generator waste heat, which further reduces electricity needs and emissions. Results showed that maximum levels of ozone and particulate matter could increase slightly in Southern California because of more distributed ge...Other highlights in the August 16 JNCI
...aly, and colleagues exposed ten neuroblastoma cell lines and cells from three pediatric patients to bortezomib and watched the drug's effect on cell growth, proliferation, and apoptosis. They found that bortezomib caused tumor cell death and inhibited blood vessel formation, or angiogenesis. Moreover, bor...Fatty spheres loaded with siRNA shrink ovarian cancer tumors in preclinical trial
...Mice infected with three human ovarian cancer cell lines derived from women with advanced cancer were treat...so held up in experiments with ovarian cancer cell lines resistant to docetaxel and to the chemotherapy drug cisplatin. The FAK-silencing liposome and the...ACS News Service Weekly PressPac -- August 9, 2006
... with a non-toxic water solution. "Temporary field lines and logos for sports complexes and roadway markings, as well as coatings for plants, fruit and the body are just a few examples that underscore where removable coatings could be applied," the researchers said in the paper. ARTICLE # "Removable Colo...News tips from the Journal of Neuroscience
...duced DNA synthesis and cell proliferation in cell lines and reduced tumor growth in nude mice implanted with medulloblastoma cells. The antigrowth activity of mGluR4 activation appeared to be mediated by inhibition of adenylyl cyclase and decreased activity of the phosphoinositol-3-kinase pathway....Neural stem cells derived from human embryonic stem cells carry abnormal gene expression
...f the federally approved human embryonic stem cell lines proved to be inferior to neural stem cells derived...donated fetal tissue. The question: would the cell lines be the same and mirror the normal neural stem cells found in humans or would one cell line be superi...Human embryonic stem cells display a unique pattern of chemical modification to DNA
... researchers analyzed 14 human embryonic stem cell lines from diverse ethnic origins, derived in several different labs, and maintained for various times in culture. They tested over 1500 potential methylation sites in the DNA of these cells and in other cell types and found that the embryonic stem cells ...Scientists map the flight of the bumblebee
... be mostImportant, helping them to fly in straight lines and to use landmarks as clues. At very close range (no more than a metre or two) they use odour to find their way around. Co-researcher, Dr Mark O'Neill, is plotting the bees' journeys using a computer programme, allowing him to build up a patter...New paradigm will help identify leads for drug discovery
...sted large numbers of compounds on engineered cell lines and proteins. Still, due to technical demands and limitations, such screening generally has remained focused on a single concentration of each compound. To address the limitations of traditional high-throughput screening, the NIH Chemical Genomics...When biology gets 'Quirky,' scientists turn to math
... a reaction). The graphs are maps of a sort, where lines and curves connect chemicals like roads connect destinations. Craciun is now an assistant professor of mathematics and biomolecular chemistry at the University of Wisconsin. Based on the number of connections and how they overlap, Feinberg and Crac...Preclinical study shows chronic stress agitates ovarian cancer; reducing stress slows tumor growth
...act, we found them in 17 of 19 ovarian cancer cell lines we tested." After three weeks, the researchers measured the number and size of tumors in the mice. The number of tumors was 2.5 times greater in the mice that had been in the 2-hour stress group and 3.6 times greater in the 6-hour stress group compa...Titans of biodiversity science call for united, authoritative voice to inform decision-makers
...odiversity experts, which would operate on similar lines to the Intergovernmental Panel on Climate Change (IPCC). Although protected areas have slightly increased during the past few decades, collectively they contain only a small fraction of the world's terrestrial species and ecosystems, and the situat...Study confirms males/females use different parts of brain in language & visuospatial tasks
...volved displaying a fan of eleven lines, with nine lines in blue and two in yellow. Above the fan was a pair of yellow lines oriented in either the same or different positions as the two yellow lines highlighted in the fan. ...'Lord of the Rings' director makes donation to UCI stem cell research
... generate up to five new human embryonic stem cell lines to be used for research. ...Sperm created in the laboratory from embryonic stem cells produce viable progeny
...this study establish that the ES cell derived cell lines can produce functional sperm in the laboratory which can be used to successfully fertilize eggs and support full-term development into embryos and adult mice. "Our approach provides an accessible in vitro model system for studies of mammalian gametog...AACR awards $2.6 million in grants for metastatic colon cancer research
...GF P1GF. Antibodies to P1GF will be used in cell lines and xenograft models. The approach has strong pot...f Colorectal Cancer Metastases." Using colon cell lines and xenografts, this study will examine the role of tissue hypoxia in colorectal hepatic metastases ...PIMCO founder and wife donate $10 million to stem cell research at UCI
... generate up to five new human embryonic stem cell lines to be used for research into treatments for spinal cord injury and diseases such as diabetes and Parkinson's disease. "This gift is immeasurably important for allowing our talented scientists to continue their work with stem cells, and to recruit m...New genes implicated in rheumatoid arthritis
...rray analysis was applied to lymphoblastoid B cell lines (LCLs) from 11 pairs of monozygotic twins, all with one healthy and one RA-affected twin. A revolutionary DNA technology, microarray can be used to not only compare gene expression in two different tissue samples, but to examine the expression of th...Protein tied to usher syndrome may be hearing's 'Missing Link'
... Guy P. Richardson, Ph.D., and others used several lines of evidence to identify a protein that Drs. Goodyear and Richardson had earlier found to comprise tip links in the inner ears of young chicks. The protein is referred to as the "tip-link antigen" (TLA) because it induces the production of special ant...