Researchers discover gene mutations for Parkinson's disease
...ase in the Basque families and the other which was linked to the disease in the English family. "The discovery of this cluster of Basque families with Parkinson's disease helped us to narrow the genetic region we were interested in," Dr. Singleton says. Once the genes for a particular complex trait or dis...Reductions in blood oxygen levels in newborns could contribute to ADHD development
... is the first time, however, that researchers have linked repetitive reductions in blood oxygen levels during a period of critical brain development to long-lasting deficiencies in release of dopamine specifically within the striatum, which is one of the brain regions important in modulating behavior, learn...OHSU scientists identify key gene that delays female puberty
... has suggested that if this is the case, it may be linked to the nation's obesity crisis." Prior to the research to be reported at the Society for Neuroscience meeting, Ojeda's group performed studies with rats showing that the TTF-1 gene is expressed in a discrete cellular subset of the hypothalamus duri...Study at Joslin shows ease of introducing technology to kids with diabetes
...ireless-equipped personal digital assistant (PDA), linked with blood glucose management software and DiaBetNet, could assist in diabetes management among youth. "Research has shown that more frequent monitoring of blood glucose levels improves diabetes control, so we've been looking for approaches that enc...New center to map DNA of key lab mice
...dentifying which gene-environment interactions are linked to disease in humans," said Dr. William Schrader, Director of the Center. "We'll start by mapping the DNA of 15 strains of mice most often used by researchers to study susceptibility to specific diseases. Then we can determine which diseases develop...Children's Hospital Boston geneticist awarded for research on muscular dystrophy
...eins and the more than 40 genes that have now been linked with various muscular dystrophies. His lab is using microarray (gene chip) technology to systematically examine the activity of multiple genes at once, seeking to find patterns common to all muscular dystrophies and those distinct to particular form...GENEPI: a tool to refine and fine-tune radiotherapy treatment for cancer
... all across Europe. A databank in Brussels will be linked to decentralised tissue banks (tumour, skin and blood samples from cancer patients and skin and blood samples from individuals without cancer) in several European countries. After obtaining informed consent, anonymous, coded clinical details will be ...Munching microbes could cleanse arsenic-contaminated groundwater
... for example, chronic exposure to arsenic has been linked to serious medical conditions, including hypertension, cardiovascular disease and a variety of cancers. "The threat extends to Central Illinois, where there are very high levels of arsenic contamination in a number of wells," said Craig Bethke, a pro...Warning from new SLU research: Usual test for vitamin deficiency can mislead doctors
...detect a deficiency of the vitamin, which has been linked to several neurological conditions, according to Saint Louis University research. The findings were presented this month at a meeting of the American Neurological Association. "B12 deficiency is associated with dementia, peripheral neuropathy...Scientists closing in on nerve proteins' contributions to memory and hearing loss
... they've connected neuregulin-1 (Nrg-1), a protein linked to schizophrenia, and postsynaptic density protein...pects age-related decreases in Nrg-1 levels may be linked to hearing loss and memory loss, and has begun testing mice genetically modified to make more Nrg-1 ...'Broken' gene reveals evolution of salt retention and possible ties to hypertension
...eared in a Chinese text on herbal medicines, which linked dietary salt to high blood pressure. "Too much salt in food endangers the heart," notes the Yellow Emperor's Classic of Internal Medicine, "the pulse hardens, tears make their appearance and the complexion changes." About two thousand years later,...Stress impairs thinking via mania-linked enzyme
An errant enzyme linked to bipolar disorder, in the brain's prefrontal cortex, impairs cognition under stress, an animal study shows. The disturbed thinking, impaired judgment, impulsivity, and distractibility seen in mania, a destructive phase of bipolar disorder, may be ......es and has cross-walls," Xiao said. "But can it be linked to the embryos?" Upon examination of more embryos collected from the original site, Xiao's research team has discovered some embryos that may be at the hatching stage. He will report on this latest finding at the Geological Society of America meeting...Plentiful fossils of dinosaur contemporary allow population study
...Casey said that such preservation trends are often linked to environmental factors rather than any intrinsic differences between the fossils themselves. "These specimens were preserved at the bottom of a lake, where there was not much oxygen. In that environment, there were not many scavengers. Perhaps ther...New study reveals locations of possible Alzheimer's genes
...isease. If confirmed, they will be the first genes linked to Alzheimer's disease since ApoE4 was discovered ...t genes, but so far only one gene, ApoE4, has been linked conclusively to the disease. Finding the other genes will be a huge step toward understanding how Al...Genetic variant linked to weakened heart pumping
...elops in many patients, they said. The researchers linked the genetic variant to a reduction in the left ventricle's ejection fraction, a measurement cardiologists make of how much blood the heart pumps with each beat. The variant, or polymorphism, involves peroxisome proliferator-activated receptor-alpha (...Old riverbed keeps chemicals from entering Ohio River
...ana. He found that the dry riverbed is still linked to the present-day Ohio River by old channels filled with sand and gravel that lie beneath the surface. Water flows between the buried aquifer and the present-day river in a kind of seesaw motion -- with the chemical pool caught in-between. Wha...New gene target found for common brain tumors in children
Scientists at Johns Hopkins have linked a stem-cell gene to a portion of one of the most common childhood brain cancers, opening the door to tailored therapies that block the gene's tumor-promoting ability. The gene, called Notch2, whose pathway is known to be an important factor in regula...Declining fish supply linked to wildlife consumption in West Africa, Science study reports
...Brashares considered other phenomena that could be linked to bad fishing years. "I wondered if I could uncover a signal linking fish supply to wildlife declines and the bushmeat trade," said Brashares. While scientists had previously considered this possibility, there were no clear data linking fish suppl......nd that the productivity of the sea is intricately linked to sediments that generate nutrients and food for other organisms such as fish. In places where human activities have disrupted marine sediments, such as the enormous "dead zone" in the Gulf of Mexico - where excess fertilizers are dumped by the Miss...