Does the desire to consume alcohol and tobacco come from our genetic makeup?
...nsion (high blood pressure) and dyslipidemia (high lipids levels in the blood). (These variables were important because the excessive use of alcohol and tobacco may cause cardiovascular disorders like hypertension, so finding the genomic determinants behind alcohol and tobacco use may point to novel mechan...Abnormal fat metabolism underlies heart problems in diabetic patients
...red in beef hearts and is one of the most abundant lipids in heart tissue. This lipid has unusual physical p...ed a way to distinguish it from the numerous other lipids found in heart cells. Fortunately, Gross and his colleagues have been developing and refining a high......ss results in increased levels of pro-inflammatory lipids being released into the mothers milk. Ingestion of this toxic milk sets off an inflammatory response in the skin of nursing pups, which ultimately disrupts the hair growth cycle and renders them largely bald. In fact, treatment with the common anti-i...Metabolic syndrome -- don't blame the belly fat
... food energy -- can promote an elevated pattern of lipids or fats in the bloodstream that underpins the metabolic syndrome. The study was led by HHMI investigator Gerald I. Shulman and Kitt Falk Petersen, both of the Yale University School of Medicine. Coauthors of the paper were from Yale and Harvard Med...Consumption of small amounts of dark chocolate associated with reduction in blood pressure
...g without changes in body weight, plasma levels of lipids or glucose. Hypertension prevalence declined from 86 percent to 68 percent. Systolic and diastolic BP remained unchanged throughout the treatment period among those in the white chocolate group. Dark chocolate consumption resulted in the short-term a...Omega-3 fatty acids protect eyes against retinopathy, study finds
...rd Medical School. By identifying the fatty acids, lipids and growth factors involved in both the disease an...y decrease the occurrence of ROP. This changing of lipids by dietary means may also translate to AMD and diabetic retinopathy. If clinical trials find that su...High cholesterol diets modify gene expression in atherosclerosis
...ferentiated and proliferative cells, able to carry lipids in culture. In this sense, cells from animals fed with control diet represent a difference. Experts carried out an early cell atherosclerosis experimental model with chickens, as these birds develop atherosclerosis very rapidly: a 20-day high cholest...JCI table of contents -- June 1, 2007
...ry or in response to abnormally elevated levels of lipids in the blood in mice. They suggest that this possibly occurs through excessive thrombin signaling through protease-activated receptors. They go on to show that these symptoms were improved by supplementation of human HCII to HCII-deficient animals, w...Story ideas from the Journal of Lipid Research
...called ATP-binding cassettes (ABCs) that transport lipids and other molecules inside and outside cells, but for many affected individuals, the causes of the disease is still not well known. Marja-Riitta Taskinen and colleagues examined how the first steps of the transport of cholesterol into the liver wer...Weill Cornell pharmacologist receives prestigious NIH MERIT Award
...nd the ways in which cell receptors, transporters, lipids and other key molecules move within and between cells (2006); Dr. William Muller, for research promoting a greater understanding of the specific processes of inflammation and methods to control them (2005); and Dr. Aaron J. Marcus, for the developmen...Fat screen delivers plant-derived chemical with antidiabetic effects
...onoz said. "If the body becomes less able to store lipids in fat, it may deposit in other tissues," where it can spur disease. Despite their efficacy, the development and clinical use of TZDs is limited by adverse effects such as fluid retention, weight gain, congestive heart failure, liver toxicity, and ...Story ideas from the Journal of Lipid Research
... on "lipid post-translational modification" or how lipids are added to proteins after they are produced in the cell. The other articles in the series appeared in previous issues of the journal. All thematic review articles and can be accessed at: http://www.jlr.org/ (under "Thematic Reviews"). How L...How does soy promote weight loss? University of Illinois scientist finds another clue
...es that are induced in the body to help us degrade lipids and reduce body weight, but it did so by boosting metabolism and not by reducing food intake," she said. To compare soy peptides with leptin, de Mejias graduate student Nerissa Vaughn, with the help of associate professor Lee Beverly, implanted can...A cherry on top: Tart cherries may alter heart/diabetes factors
... it, and it is important in the formation of blood lipids like LDL, typically known as the "bad cholesterol"...in muscle, and on the production of specific blood lipids like LDL and HDL. In addition, they will characterize cherries chemically, to assess the levels of p...Different approach needed to protect brains of premature infants
... cells supply this sheath, which is made mostly of lipids and makes about 50 percent of the human brain appear white, rather than gray. Goldberg and others have been developing a theory that much of the harm done by strokes and other brain injury begins in this white matter. They suspect that damage to conn...New study zeroes in on genetic roots of Alzheimer's
...ina combination of fat and protein that transports lipids (fats) in the bloodknown as apolipoprotein (Apo) E4. Studies have found that those who inherit the E4 gene from one parent are three times more likely than average to develop Alzheimer's, while those who get the gene from both parents have a tenfold ...Newly discovered 'platform' for processing dietary fat
...transported to the capillaries, where the packaged lipids are taken apart. The fat "bundles" have to be broken down because the lipids are otherwise unable to get across cell membranes, Beigneux added. The researchers "stumbled onto"...Stem cells act through multiple mechanisms to benefit mice with neurodegenerative disease
...atsix months in human infants. The accumulation of lipids in brain tissuedestroys the brain cells instrument... 50 diseases rooted in the inability to metabolize lipids or othermaterials. While Sandhoff and Tay-Sachs are relatively rare, one personin 5,000 is affected ...Bacterial walls come tumbling down
...ber of a family of enzymes that remove sugars from lipids and attach them to other sugars. This process is used in a wide range of biochemical reactions, including allergic responses and cell signaling in cancer.......nsulin resistant and blood sugar and certain blood lipids gradually creep up, which can cause progressive damage to multiple organs." Urocortin 3 is the second urocortin peptide that this laboratory has found to restrain insulin production or action. In a study published last October in Proceedings of the...