Hepatitis C virus linked to non-Hodgkin's lymphoma
...) are six times as likely to develop non-Hodgkin's lymphoma (NHL) than individuals that are virus free, accord... British Columbia documented. Diffuse large B-cell lymphoma is the most common variety of NHL, comprising approximately 30 percent of all NHL patients. Compare...UCLA scientists discover new way to fix defective gene
... in childhood. One in three children also develop lymphoma or leukemia. Adults who carry the mutated A-T gene (ATM), including up to 15 percent of breast-cancer patients, are eight times more likely to develop cancer than the general population. Dr. Richard Gatti, professor of pathology and laboratory med...Consuming fruits and vegetables lowers risk of developing NHL
...xidant vitamins may reduce the risk of non-Hodgkin lymphoma (NHL), a form of cancer of the lymphoid tissue. The results of this study, conducted by the National Cancer Institute and four academic centers in Iowa, Seattle, Los Angeles and Detroit, show that individuals who consumed three or more servings ...By impounding iron, FHC foils cell suicide, fuels inflammation
...wel disease and certain cancers, such as Hodgkin's lymphoma and multiple myeloma. But the tasks controlled by NF-kB are so wide ranging that blocking them globally can have serious side effects, such as reduced ability to fight off an infection. "The goal has been to find new compounds that disrupt unwanted...Cloned gene from sea animal may prove key in cancer drug development
...otential asanticancer pharmaceuticals in leukemia, lymphoma and several cancers including colon, breast, ovarian and prostate. One of the main obstacles impeding widespread bryostatin production is lackof a practical and economically viable method of producing the compounds.The bacteria cannot be grown in lab...Source of molecular triggers in cutaneous T cell lymphoma identified
...te first identified CTCL as a separate category of lymphoma thirty years ago. The Yale research group reported that, like all T cells, the cancerous CTCL cells require antigenic stimuli delivered by specialized dendritic cells of the epidermis, referred to as Langerhans cells (LC), in order to replicate. To ...Compound inhibits one critical pathway in breast cancer growth
...ad and neck, skin, pancreas and ovaries as well as lymphoma and certain kinds of leukemia. Stat3 is constantly activated in about 60 percent of breast tumors, said Jiayuh Lin, the study's lead author and an associate professor of pediatrics at Ohio State University. All cells contain Stat3 protein, but in nor...Cure no quick fix for cancer survivors on long road to recovery
...o had breast cancer, acute or chronic leukemia, or lymphoma -- among the most common indications for transplantation. Researchers at UF, Northwestern University, the University of Kentucky and the Medical College of Wisconsin interviewed participants by telephone and asked them to describe their quality of li...TEL2 gene cooperates with MYC gene to provoke B-cell lymphomas
...rent issue of Molecular Cell Biology (MCB). B-cell lymphoma is a cancer in which the antibody-producing cells ...d. "Instead, this gene promotes the development of lymphoma by enlarging the B lymphocyte population. This increases the likelihood that at least a few of the c...U of T researchers map role of Epstein-Barr virus in cancer
...ly linked to certain b-cell cancers like Burkitt's lymphoma as well as the epithelial cell cancer, nasopharyngeal carcinoma. EBNA1 is a protein coded in the Epstein-Barr virus and suspected to play a role in the development of cancer," says Lori Frappier, professor in medical genetics and microbiology at U of...Lance Armstrong Foundation supports UHC research
...breast cancer survivors, the impact of exercise on lymphoma survivors, the psychological late effects of cancer and the fertility of women following chemotherapy for early breast cancer. "We are thrilled to be partnering with top-notch institutions and researchers in the early stages of their careers like ...Other highlights in the April 20 JNCI
...-are associated with a reduced risk of non-Hodgkin lymphoma (NHL), according to a new study. Immune deficiency is a strong risk factor for NHL, which arises from cells of the immune system. Whether atopy--another form of immune system dysregulation that is characterized by certain hypersensitivity reactions, ......ugate into mice that had been implanted with human lymphoma cancer cells. As predicted, the Rituximab, with th...urface. Within three days, almost all of the human lymphoma cancer cells were destroyed in those mice treated with the conjugate and alliin, while hardly any ca...Viral protein influences key cell-signaling pathway
...he infection will lead to adult T cell leukemia or lymphoma (ATLL). ATLL is an aggressive disease characterized by a long latent period and the proliferation of T lymphocytes. The virus is spread by sexual activity, by contact with infected blood and by infected women to children through breast milk. HTLV-1,...USC researchers determine mechanism of action of chemotherapy drug
... properties of cells from human lung, prostate and lymphoma cancer cell cultures that had been treated with motexafin gadolinium, or MGd. What they found was that the drug created oxidative stress in the tumor cells, increasing the levels of expression of the genes that produce metallothioneins. The researche...Columbia dedicates new 300,000 sq. ft. Irving Cancer Research Center
...ding brain, breast, gastric, pancreatic, prostate, lymphoma and tumor immunology. The ICRC is part of the Her... one of the world's leading cancer geneticists and lymphoma researchers. "This is a historical moment in our cancer research. In the last 20 years enormous prog...Columbia University researchers create mouse model that develops a human-like lymphoma
...have created the first mouse model that develops a lymphoma the same way that humans do. This advancement has...f new, improved therapies for diffuse large B cell lymphoma (DLBCL), the most common type of human B cell lymphoma. Human B cell lymphomas cause 85 percent of ...Protein targets tumor vasculature, delays tumor growth in animal study
...ered systemically to mouse models of human Hodgkin lymphoma and small-cell lung carcinoma and a mouse model of small-cell lung carcinoma that contained human tumor vasculature. A single systemic administration of the fusion protein led to tumor tissue death. Long-term treatment produced delays in tumor growth......expressed at abnormally high levels in four B-cell lymphoma cell lines in which the mir-17-92 cluster was ampl...ompared to normal B-cells and to five leukemia and lymphoma cell lines in which the mir-17-92 cluster was not amplified. The researchers found that indeed, five......7-92 miRNA gene activity in human tumor samples of lymphoma and colorectal cancers. They found overexpression of the miRNA genes in the former but not the latter. "That finding gave us confidence that we might be looking at something that would be clinically relevant," said Hannon Finally, the researchers tes...