New therapy for specific form of leukemia
...n of normal blood cells. Among other effects, this makes patients more susceptible to infections. Leukemia appears in several forms − in the case of T-ALL, a large accumulation of immature white blood cells occurs within a very short time. This is the most common type of cancer in children under the ...NIH funds first nationaL SNP genotyping center at Broad Institute
...ion. "The tremendous potential of genetic research makes it critical that we develop this central resource so investigators around the country can access high capacity genotyping with the additional benefits of economies of scale, quality assurance and data sharing," said NCRR Division for Clinical Researc...New biosensor rapidly detects deadly foodborne pathogen
... but only L. monocytogenes can infect humans. This makes it especially important to develop highly selectiv...ty to distinguish this one species from all others makes this a very powerful sensor. No other sensor today can do that," he said. The sensor also is s...'Immediately open access' option for the leading journal Genome Research
...tral ( www.pubmedcentral.nih.gov ). The Press also makes its journals available free of charge online to scientists in the poorest countries through the HINARI ( www.healthinternetwork.org ) and AGORA ( www.aginternetwork.org ) projects. "We are pleased to expand the service we offer the scientific communi...Biologists ID molecular block for social 'cheaters'
...nd evolutionary biology at Rice. "Such a mechanism makes the loss of social genes costly to cheaters, and we believe this pleiotropic mechanism may be indicative of a general mechanism that's employed in many species to stabilize cooperation." The Rice-Baylor experiments draw upon one of the most extraordi...Botulism bug says no to nitric oxide, provides key to molecule's role in human cell signaling
...or his 1977 finding that NO is the ingredient that makes nitroglycerine beneficial to heart patients. Since then NO has been found to govern many other vital biological functions and became the basis for medications that treat erectile dysfunction. However, the structural details of soluble guanylyl c...US Agency for International Development awards $34 million to Virginia Tech
...f global concern. The second $17-million award makes Virginia Tech the lead institution and the management entity in the Sustainable Agriculture and Natural Resource Management Collaborative Research Support Program (SANREM CRSP), which was formerly managed by another land-grant university with Virgini...UF scientists have bionanotechnology recipe to find elusive bacteria
...e potential health risks. "Sometimes one bacterium makes the difference," Tan said. The secret to the UF team's super-sensitive method is in the sauce: The silica structure they use to bind the antibody-and-dye amalgam together allows each particle to hold thousands of dye molecules, rather than just one...Award-winning INEEL probe to help safely monitor hazardous waste sites
...orkers save time and money, Jones says. GEOPS also makes it easy to gather extensive, accurate data quickly, Jones says. Having sensors consolidated in one place saves scientists from needing to piece together incomplete information from various locations. And since the probe area is undisturbed by digging...Muscling in on a deadly cancer
...tem cells, the embryos didn't develop tumors. That makes satellite cells an unlikely source of the cancer. Scientists who reviewed the paper argued the cancer could still originate in rare subtypes of muscle stem cells. Keller and Capecchi plan to test those cells. But Keller says that wh...Ancient Chinese folk remedy packs anti-cancer punch
... is released and reacts with the artemisinin. That makes the compound both highly toxic and, because of cancer's rapacious need for iron, highly selective. Surrounding, healthy cells are essentially undamaged. "Our research in the lab indicated that the artemisinin-tagged transferrin was 34,000 ti...Perceptual decision-making hub pinpointed in human brain
...tual decision-making hub at the front of the brain makes the call on whether you're looking at a face or a house and likely many other things scientists at the NIH's National Institute of Mental Health (NIMH) have discovered. It works by gauging the strength of competing signals from lower brain areas sp...Research gaining momentum by silencing genes
...d RNAi is one such technology. This new technology makes it possible to prevent the production of a protein with a specifically designed fragment that turns off the coding gene. The removal of the protein then induces alterations in the plant during its development, and from these alterations researchers c...Delay in cutting the cord helps premature babies
...t it's not even recorded on hospital charts, which makes it hard to do even retrospective studies," says Judith Mercer, C.N.M., D.N.Sc., of the University of Rhode Island, who has studied the issue. Despite concerns for the baby's respiratory status, the trials covered in the review offered little guidanc...UT Southwestern researchers uncover process for sugar-induced fat formation
.... Miller said. "This is significant because ChREBP makes sure that glucose is only converted to fat when it is in excess. It coordinates glucose breakdown and energy storage via fat." Other contributors to the first study were Drs. Katsumi Iizuka and Guosheng Liang, former postdoctoral fellows;...Hormone therapy's effect on breast density is not the same for all women, Group Health study finds
...e therapy, increases breast density, a change that makes it harder to detect breast cancer on mammograms. But it hasn't been clear whether this increase happens for all women, or whether it differs based on various breast-cancer risk factors, the type of HT a woman uses, and the length of time she takes it...To save dolphin's dorsal fin experts combine medical technology and teamwork
...ector at Dolphin Quest Hawaii. "Liko's cooperation makes him a key member of his own medical team and has gone a long way to improve his chances of a successful recovery." "When we first put Liko's medical team and treatment plan together, we were outwardly hopeful, but harbored some serious doubts that we...Mice thrive despite massive genetic makeover
...on-coding DNA (sometimes called "junk DNA")--which makes up nearly 98 percent of the genome--required, or is some of it potentially disposable? "In these studies, we were looking particularly for sequences that might not be essential," said Eddy Rubin, Director of the JGI, where the work was conducted....For inferring the biological tree of life, simple is better
...dels are usually wrong," Thornton said. "Parsimony makes fewer assumptions, so it can cope with a complex reality better." The results published in Nature suggest that scientists should bring back the maximum parsimony method and interpret with caution results from the maximum likelihood method, many of wh...... protein-coding component of these genes, however, makes up just a small fraction of the human genome about 1.5 percent. There is strong evidence that other parts of the genome have important functions, but very little information exists about where these other "functional elements" are located and how th...