Annals of Internal Medicine tip sheet for Oct. 5, 2004
...reventable Although indigenous transmission of malaria was eradicated from the United States in the late 1940s, every year about 1,500 malaria cases occur. Most infections occur in people who travel abroad, and one of every 100 U.S. travelers ...Report: How 10 top new technologies will help world reach globally-agreed goals by 2015
...kly and accurately diagnose diseases like AIDS and malaria top a list of 10 biotech breakthroughs deemed most... mortality; Improve maternal health; Combat HIV, malaria and other diseases; and Ensure environmental sustainability. If not properly harnessed, the expert...New technique targets pesticide-resistant insects
...o has potential for public health programs such as malaria control." An Italian company is working on a commercial release for a formulation designed on this technology which, in the first instance, will be available for use on cotton. It is expected subsequent formulations will be developed for other agricu...Cooperation to create a new tuberculosis vaccine
... 9 million new infections annually, TB, along with malaria and HIV/AIDS, is responsible for the greatest number of infectious disease victims world wide. Of particular concern is the increasing number of pathogens resistant to conventional medication. The World Health Organisation estimates that some 50 mill...Ancient Chinese folk remedy packs anti-cancer punch
...in about 10 years ago. The chemical helps control malaria because it reacts with the high iron concentrations found in the single-cell malaria parasite. When artemisinin comes into contact with iron, a chemical reaction ensues, spawning charge...The long road to a promising malaria vaccine started at NYU School of Medicine
NEW YORK, October 15, 2004 -- The malaria vaccine reported today to reduce life-threatening ..., the vaccine reduced life-threatening attacks of malaria by 58 percent, and reduced milder forms of the disease by 30 percent. The study is published in the ...Genetic data crunching achieves milestone at Stanford
...entists to understand how various drugs affect the malaria bug, to find out what the immune system attacks in patients with autoimmune diseases and to pinpoint genes involved in multiple sclerosis. Sherlock estimates the database now supports 400 campus researchers doing work on 30 different organisms (more ...Insects implicated in the evolution of new human infectious diseases
...sects which can carry devastating diseases such as malaria into the Northern hemisphere." In the case of Photorhabdus luminescens, the infection is naturally resistant to several antibiotics but the relapsing infection can be combated using repeated administration of certain drugs. The researchers predict t...Studies in Royal Society journals include stress in birds and depletion of medieval fish stocks
...ltiple-strain pathogen diseases such as influenza, malaria and HIV using a mathematical model at an arbitrarily large number of strains interacting via cross-immunity and in the presence of mutations and extinctions. Cross immunity is a phenomenon where infection by one strain induces partial immunity to fut...Dream home: Malaria parasite renovates to suit its tastes
The malaria parasite survives in its host by remodelling the r...eam have identified the mechanism that enables the malaria parasite Plasmodium falciparum to export proteins across a cell membrane to establish infection in t...$43 million from Gates Foundation to produce inexpensive antimalarial drug for Third World
..., of Albany, Calif., to develop the technology for malaria treatments. In exchange, Amyris will produce the drugs at cost, and OneWorld Health will perform the detailed non-clinical regulatory work that will be required by United States and other global agencies to allow the low-cost, microbially-based produ...MIT team engineers new approaches to understanding malaria, more
... thought he'd be a player in the hunt for cures to malaria and pancreatic cancer. It turns out, however, that...l provide a deeper scientific understanding of how malaria affects cells by bringing cutting-edge engineering methodology to study medical problems," Suresh sa...Science's Breakthrough of the Year: Salty, acidic soup could have supported life on Mars
...veral prominent initiatives this year, including a malaria vaccine trial and efforts to provide anti-HIV drugs. Genes in a Drop of Water: In 2004, researchers hit on a new way to identify life forms too small and remote to see with the naked eye. They collected water from environments as different as the S...UGA partners with U of Pennsylvania for bio-defense and infectious disease research project
...m Apicomplexa, which includes organisms that cause malaria and toxoplasmosis. NIAID, part of the National Institutes of Health, awarded a total of eight contracts in 2004 to establish national Bioinformatics Resource Centers, including the Penn/UGA award. Jessica Kissinger, assistant professor of genet...Scientists reveal molecular secrets of the malaria parasite
In an innovative project with implications for malaria vaccine development, scientists have used genomics...roteomics and gene expression studies to trace how malaria parasites evolve on a molecular level as they move between their hosts and insect vectors. That focu...UCI researchers create new technique for speeding development of vaccines
...ines against infectious diseases such as smallpox, malaria and tuberculosis. Because the new technique can synthesize a large number of proteins very quickly, it has potential to accelerate vaccine development, particularly crucial in the fight against bioterrorism. The technique is based on "polymerase chai...Examination of internal 'wiring' of yeast, worm, and fly reveals conserved circuits
...ce of every gene in the genomes of everything from malaria pathogens and mosquitoes to mouse and human. Databases of genomic information have been combined with databases that list the precise subunit sequence of proteins as well. Cross-species DNA and protein comparisons have become routine for all biologis...Researchers blend folk treatment, high tech for promising anti-cancer compound
...se throughout Asia and Africa. Artemisinin combats malaria because the malaria parasite collects high iron concentrations as it metabolizes hemoglobin in the blood. As science beg...Ecological destruction fuels emerging diseases
...gs are coming from." In fact, while parasites like malaria are well known, we may have identified only a fraction of the total number of the world's parasites, and the prospect of cataloguing them poses a daunting technical challenge. Since the physical characteristics of many parasites are very similar, Dr....Ancient olfaction protein is shared by many bugs, offering new pest control target
...ages corn and tobacco), and Anopheles gambiae, the malaria mosquito. When the medfly, moth, and mosquito versions (or "orthologues") of Or83b were expressed in fruit flies that were missing their own version of the gene, the flies' sense of smell was restored, arguing not only that the gene's sequence has be...