Researchers find protein that makes long-term memory possible
...remember things for more than a day--sometimes for many years. Scientists have suspected that BDNF played a role in memory, but had not known whether it exerted its effect directly, or in combination with other substances. The first clue came in 1996. Then, Dr. Lu and his colleagues reported in N...Using fruitflies to examine alcohol tolerance
...ly sophisticated nervous system and are capable of many well-characterized complex behaviors, including re...e octopamine. By testing flies with mutations for many other genes, the authors will be able to test more rigorously their suggestion that different geneti...Identifying genes that contribute to a low level of response to alcohol
...ur hands." Schuckit added that he plans to test as many of the genes as he can. "It's very difficult work, expensive and time-consuming," he said. "We will be focusing on several chromosomal regions, several specific genes, and continue to collaborate with people doing animal research."...S1P1 essential for tumor growth and is blocked by RNA interference
...l growth, a process called angiogenesis. There are many factors involved in the nor-mal growth and stabilization of new blood vessels. One of these, sphingosine 1-phosphate receptor 1 (S1P1), is required during embryonic development to stabilize new blood vessels. Timothy Hla and colleagues, from the Univ......e, then watched what happened. They found that many of the mice died before birth. Those that lived are markedly smaller than their normal counterparts: They're born far smaller and then make up some of the difference as they grow, but generally they are about 20 to 30 percent smaller by the time they...Scientists identify new cause of obesity
..., and mutations in the receptors are implicated in many diseases. The new research provides the first evidence of an essential role for the basal activity of a GPCR in controlling a normal human physiological function, the scientists report. "Our genetic findings highlight the importance of patient partic...Study confirms link between head and neck cancer and common Asian nut
... Chewing betel quid, traditionally practiced in many parts of Asia and in Asian-immigrants around the w...nd a slice of areca nut. Betel quid is chewed for many reasons, including for its stimulant effects, to satisfy hunger, to sweeten the breath, and as a soc...Delay in cutting the cord helps premature babies
...ortable with the 30-second delay, but there are so many things that can happen with a preterm infant that ..., delaying clamping too long can actually pack too many red blood cells into the baby's system. That can make the blood too thick, stressing the heart and r...UCLA scientists discover new way to fix defective gene
...based therapy for this group." According to Gatti, many aminoglycosides are already approved for clinical use by the FDA and could quickly become available for testing in A-T clinical trials. "Our next step will be to build an ATM animal model and see how it responds to aminoglycoside therapy," said Gatti...An old adage about apples finds scientific backing
...gely in the apple's skin. An antioxidant is one of many chemicals that reduce or prevent oxidation, thus preventing DNA, cell and tissue damage triggered by free radicals in the body. As part of their study, the French scientists split the polyphenols found in apples into two general categories: polyphen...Rutgers is on the 'NIH Roadmap'
... and NIH-led research has changed the landscape of many diseases," Zerhouni said. "However, very real and...machines is particularly relevant to understanding many diseases, such as cancer and metabolic disorders. The virtual Computational Center for Biomolecular ...New version of tumor-suppressor linked to progression of childhood cancer
...vous system. Mutated TrkA has been associated with many human cancers, including colon, thyroid and prostate cancers. However, previous studies have suggested that TrkA acts as a tumor-suppressor in NB. Dr. Andrew R. Mackay and colleagues from the University of L'Aquila in Italy found a previously undisco...Discovery might improve design, effectiveness of anti-cancer drugs
...dine deaminase, which is derived from bacteria and many other sources, mark the first time that scientists...he fact that this protein 'water bottle' flies for many seconds through a nearly perfect vacuum into which the water molecule would evaporate instantly if i...Peakadilly nv biopharmaceutical firm created
...ble doctors to detect diseases sooner and, because many medicines work effectively only with a limited gro...tivity of) particular proteins are at the basis of many diseases (such as diseases of the muscles and cancer), and the development of medicines focuses on r...Medical geneticists elected to Institute of Medicine
...achievements and commitment to service. Along with many others at NHGRI, these two physicians have been at the forefront of efforts to translate the findings of the Human Genome Project into new strategies for improving human health. The IOM surely will benefit from their membership," said NHGRI Director ...Manipulation of epigenome turns off as many genes as it turns on
...y in early clinical studies -- instead turn off as many genes as they turn on, a team of researchers from ... and clinical trials that use the agents, since so many genes are affected, says Feinberg. "It was kind of assumed that removing methyl groups would t......lklore and mysticism throughout the ages. Although many people claiming to have such powers could be charlatans, it is also conceivable that others are born with a gift of synaesthesia. "GW does not believe she has mystical powers and has no interest in the occult, but it is not hard to imagine ...Common gout drug shown to reduce risk from colorectal cancer
...s such, allopurinol acts as an antioxidant, one of many chemicals that reduce or prevent oxidation, thus preventing cell and tissue damage resulting from free radicals in the body. "Previous studies have focused on using antioxidants, mainly of nutritional origin, to reduce the risk of cancer," ...Consuming fruits and vegetables lowers risk of developing NHL
...h NHL in this study, vegetables and fruits contain many other nutrients that may explain the association with NHL. "Dietary modifications such as eating more vegetables and fruits are within the public's grasp to lower their risk of cancer and other diseases. We hope that these findings,...To save dolphin's dorsal fin experts combine medical technology and teamwork
...n will help other dolphins in the future and many, many other animals of all kind, as Liko's story helps introduce the concept of regenerative medicine to the veterinary field." The use of extracellular matrix for the repair of soft tissues was developed by Dr. Badylak, research professor in the departmen...