Study shows metabolic strategy of stressed cell
...tors at St. Jude Children's Research Hospital have mapped out many of the dynamic genetic and biochemical changes that make up a cell's response to a shortage of a molecule called Coenzyme A (CoA), a key player in metabolism. The results provide the most detailed look ever obtained of the complex metabolic ...News tips from the Journal of Neuroscience
...nk, and Russell A. Poldrack Aron et al. this week mapped a connection between brain regions that control cognitive "stop" signals. The authors looked for a direct link between inferior frontal cortex (IFC) and subthalamic nucleus (STN) in human subjects using diffusion-weighted imaging tractography, a form...Diffraction and scattering -- the solution to what's in solution
...tions, special CCD cameras equipped to detect them mapped out their two-dimensional pattern. The detailed results of these findings were published in the paper, "Structures of Dimeric Hydrolysis Products of Thorium" and in the journal Inorganic Chemistry. "Going forward, additional research is planned w...New imaging method shows whether treatment for advanced prostate cancer is working
... movement, of water through the cells. Researchers mapped the changes in diffusion over the course of treatment. The tumor cells slow the movement of water, so as those cells die, water diffusion increases. Researchers studied metastatic prostate cancer in mice; half the mice were given chemotherapy to tr...Tracking genes for self-pollination in arabidopsis
...searcher in Nasrallah's laboratory, and colleagues mapped the genomes of several varieties of transgenic A. thaliana in fine detail and isolated a gene known as PUB8 that seems to regulate the expression of SRK -- that is, whether or not it is turned on to manufacture its protein. The PUB8 gene shows so...Penn leads $4 million grant to study gene-environment interactions in lung cancer
...airborne pollutants. These pollutants will also be mapped cartographically using GIS technologies to ascertain distribution in each study location. Exposure to air pollutants for each subject will be analyzed together with their individual variation in approximately 100 genes. The genes to be tested are c...BCM, Rice make major advance in structural biology
...hold of the protein and twist it to fit within the mapped area, but in so doing they may inadvertently move a different part of the protein out of alignment somewhere else. The problem is magnified by the fact that only a small fraction of the entire puzzle can ever be shown on the screen at one time. The...News tips from the Journal of Neuroscience
...s or reduction of sensation. This week, Kim et al. mapped the thalamic nuclei in which damage specifically produces allodynia, a painful response to normally innocuous mechanical or cold stimuli. The subjects had experienced small thalamic strokes. The authors used somatosensory testing and atlas-based mapp...New Arizona alliance aims to boost technologies for medical diagnostics and human health
...e generated by the Human Genome Project, which has mapped roughly 25,000 genes. Each gene codes for the production of protein, but with all the modifications possible to both the gene transcript and protein, the human body could have well over a million different proteins, according to the Human Proteome I...Left-right wiring determined by neural communication in the embryonic worm
...s. Every neuron in the adult C. elegans has been mapped and named. Handedness researchers are particularly interested in two olfactory neurons, AWCON and AWCOFF, one each on the left and right side of the worm's body. AWCON has one set of responsibilities, while AWCOFF has a totally different set of funct...MIT researchers probe bones' tiny building blocks
... out a tiny fragment of bone, Ortiz and colleagues mapped the stiffness of bovine shin bone into complex, colorful, two-dimensional contour maps similar to those used by geographers. The team found that the mechanical properties of bone vary greatly within a single region only two micrometers (thousandths...Analysis reveals extent of DNA repair army
...Elledge's group studied human cells in culture and mapped their response to ionizing radiation and ultraviolet light. Specifically, the group looked to see which proteins in the cell were chemically altered by the enzymes ATM and ATR, finding 900 sites on 700 proteins that changed in response to DNA damage....Virus widely used in gene therapy research yields important clues to genomic instability
... heart. Furthermore, of 945 rAAV integration sites mapped to the mouse genome, Dr. Nakai and his collaborators found that up to 30 percent of the integration events occurred in DNA palindromesa sequence of base pairs in DNA that reads the same backwards and forwards across the double strands. A series of bi...News tips from the Journal of Neuroscience
...ses. This week, Deng et al. looked beyond the well mapped Plexin-A molecules to track the influence of neuronal Plexin-B proteins. Granule cell precursors (GCPs) of the cerebellum, the dentate gyrus, and the olfactory bulb strongly expressed Plexin-B2 mRNA within their migratory streams, but not once the ce...2007 Image of the Year: Molecular imaging relates human brain chemistry to aggressive behavior
...-Klein. The men then answered a questionnaire that mapped their personality profile. We discovered that the amount of MAO A activity in the brain of 27 healthy men corresponded to the amount of aggression they reported in the questionnaire, said Alia-Klein. The less MAO A they had in the brain, the more t...Woods Hole Research Center scientists study impacts of industrial logging in Central Africa
...r for logging expansion in Africa. Researchers mapped nearly 52,000 km of logging roads within the forested region, which includes Cameroon, Central African Republic, Equatorial Guinea, Gabon, Republic of Congo, and Democratic Republic of Congo. Prior to this work, there were few reliable data sets avai...Exploring the dark matter of the genome
...ssembly taken as far as practical, the researchers mapped the sequences to their physical locations on the c... a gene splice-site or a promoter, for example. We mapped experimentally derived evidence of messenger RNAs back to the matching heterochromatin sequence. And...Pendulum love, science class gender gaps, musical mind mirrors, and unparticle physics
...h, and timber among other factors. Researchers mapped brain activity and the compositions by regions of similarity punctuated by jumps where a significant change occurred. The data illustrated the similarity between patterns of electrical signals in the brain and of musical compositions. In addition,...MIT tool determines landslide risk in tropics
... To prepare their hazard ratings, the researchers mapped the seven types of underlying bedrock in the area, overlaid with data on slope inclination and vegetation growth. Some of their findings are a bit counterintuitive, Saldivar-Sali explained. For instance, steeper slopes don't necessarily indicate grea...... your back yard. The data retrieved are instantly mapped by the Portal. The data can also, if the user chooses, be easily plotted on Google Earth. The Data Portal is a sophisticated tool for users to incorporate biodiversity data into their own websites, or download datasets for ecological studies. W...