No evidence that widely prescribed statins protect against prostate cancer
...Hall said. In this study, statin use was just a marker for presence of other illnesses, she said. This study may inform that debate, however, by suggesting that any protective pathway offered by statins, if it exists, is not through androgen suppression. ...New test improves detection of liver cancer
...t in the blood. For the detection of HCC, only one marker (AFP) is generally used. However, this marker has a low specificity and is frequently inadequate because of false-positive results. New blood ...Aggressive therapy best for certain AML patients
...these patients. It was the first clinically useful marker to be identified in cases of AML with normal-looking chromosomes, and it was found to predict a short remission and poor response to therapy. About 8 percent of AML patients with normal-looking chromosomes have the mutation. Studies done eight to ...Molecule blocks gene, sheds light on liver cancer
...ase. This particular microRNA might also provide a marker to help determine a patient's prognosis. The study, led by researchers at the Ohio State University Comprehensive Cancer Center, is published in the August issue of the journal Gastroenterology. Our findings essentially describe a new mechanism...Gold nanoparticles may pan out as tool for cancer diagnosis
...gold nanoparticles that are capable of identifying marker proteins on breast cancer cells, making the tiny p...ped with antibodies designed to bind to a specific marker on cell surfaces. Researchers analyze these surface markers, proteins on a cell's exterior, because ...MGH researchers confirm that bone marrow restores fertility in female mice
...normal and contained immature oocytes expressing a marker protein indicating they came from the donor cells....les that express a green fluorescent protein (GFP) marker only on germline cells, which are precursor cells involved in producing oocytes. Two months after t......t-knot nematode resistance, scientists developed a marker assisted screening test that used SNPs to determin...not resistance genes are present in soybean crops, marker assisted selection can inform breeders about the presence of the resistance gene in individual plant...Nodal status is best predictor of outcome after neoadjuvant therapy for esophageal cancer
...adiotherapy for oesophageal tumours is a surrogate marker of survival advantage, explain the authors. However, the study established that it was nodal status rather than attainment of pathological response that was the most significant determinant of prognosis. When individuals with complete pathological...New blood test might offer early warning of deep belly fat
...suggests a potential role for RBP4 as a convenient marker not only for type 2 diabetes but also for cardiovascular risk, they wrote. In addition, RBP4 may provide a mechanistic link between visceral adipose tissue accumulation and the increased metabolic and cardiovascular risks associated with it. Kahn sai...U-M, Israeli scientists report major advance in search for genes associated with colon cancer
...s the leading cause of cancer deaths. The specific marker is called the C allele of rs10505477. Three othe...ns around the world suggests that this one genetic marker is highly influential across ethnic groups. The new Cancer Biology and Therapy paper is by an inte...Engineered blood vessels function like native tissue
...scle cells from bone marrow by using a fluorescent marker protein and a tissue-specific promoter for alpha-actin, a protein found in muscles that is responsible for their ability to contract and relax. Although not yet strong enough for coronary applications, the UB groups tissue-engineered vessels ...New 'asthma gene' could lead to new therapies
...e located on chromosome 17, and children with this marker had higher levels of a new gene called ORMDL3 in their blood, which occurs in higher amounts in children with asthma. The presence of the disease-associated version of ORMDL3 increases the risk of asthma by 60-70 percent, the study suggests. "In te...Manganese levels increase in scrapie-infected sheep before clinical symptoms develop
...nese levels in the blood as a potential diagnostic marker for prion infection. At present, only post-mortem ...ood manganese could be used as a robust diagnostic marker for prion infection, even before the onset of apparent clinical disease. In practice, however, it ...Antibody linked to MS significantly higher in spinal fluid of blacks
...Louis An antibody frequently used as a diagnostic marker for multiple sclerosis (MS) is present at greater levels in the cerebrospinal fluid of blacks with MS than Caucasians with the disease.The findings suggest that genetic differences among ethnic groups contribute to changes in the immune system, affec....... Beta-endorphins constitute a useful biological marker to identify specifically those subjects who have a higher risk of developing alcohol abuse, the research claims. Regarding the results of this study, professor Rico states the following: alcohol-abuse prevention must consist of locating and identif...Support for chromosomal theory of cancer found in cancers' development of drug resistance
... cells of a particular cancer have the same set of marker chromosomes, a rogues gallery of normal chromosomes and stumps of chromosomes. Duesberg and UC Berkeley postdoctoral fellow Ruhong Li showed that the karyotype of drug-resistant cancer cells differs significantly from the karyotype of drug-sensitive ...Researchers find gene that spurs development of the epididymis
...eveloping epididymis for inhibin beta A and for a marker of activin activation Yaos team was able to show that inhibin beta A was spurring activity in the cells that form the walls of epididymal tube. Further study showed that a lack of inhibin beta A led to stasis in these cells. Without it, the cells ...Fine particulate matter from traffic may influence birth weight
...rbance of particulate matter is considered to be a marker of the particles originating from traffic, and in particular from diesel vehicles. Earlier American Studies had already suggested that fine particulate matter might influence the birth weight. This recent study is the first study from Germany and W...Marker predicts pancreatic cancer outcome after surgery, Jefferson surgeon finds
...180. While CA 19-9 is a well established tumor marker for pancreatic cancer, he notes, These results all...th advanced pancreatic cancer, its use as a cancer marker is not foolproof. It may also be elevated in other cancers, conditions and diseases, such as colorec......bacterium. The hygromycin resistance gene is a marker gene to help sort out the transgenic mushroom cells from the non-transgenic cells, Dr. Romaine explained. "What we are doing is taking a gene, as for example a drug gene, that is not part of the mushroom, and camouflaging it with regulatory elements...