Researchers discover gene responsible for Restless Legs Syndrome
...uired to translate this knowledge into a plausible mechanism and, in turn, more rational and better treatments," notes Dr. Rye. "Future advances will depend upon additional monies which to this point have come solely from private foundations and industry." Dr. Rye says RLS is exceedingly common but not taug...UCLA researchers show that culture influences brain cells
...oscientists believe this "mirroring" is the neural mechanism by which we can read the minds of other people and empathize with them. When it comes to the influence of culture, they found that indeed, the mirror neuron network responds differently depending on whether we are looking at someone who shares our ......for Learning and Memory have uncovered a molecular mechanism that governs the formation of fears stemming from traumatic events. The work could lead to the first drug to treat the millions of adults who suffer each year from persistent, debilitating fears - including hundreds of soldiers returning from conflic...The origin of perennial water-ice at the South Pole of Mars
...ic explanation for the age of the deposits and the mechanism of their formation could finally be suggested. This was achieved thanks to the OMEGA mapping and characterisation of these ice deposits, combined with the computer-generated Martian Global Climate Models (GCMs). The mapping and spectral analysis ...Chromosome glue repairs damaged DNA
...ersity Karolinska Institutet have discovered a new mechanism that helps to explain how the cell performs these repairs. The results are presented in Science. The new results are concerned with a phenomenon called cohesion, whereby two copies of a chromosome in the cell nucleus are held tightly together by a ...Major breakthrough in understanding how HIV interferes with infected cell division
...process called ubiquitination. Ubiquitination is a mechanism by which a small protein called ubiquitin is conju... protein complex as well as the elucidation of the mechanism by which it affects cell division may open new avenues for therapeutic intervention against HIV. ...How plants learned to respond to changing environments
...fter colonisation of the land that the gibberellin mechanism evolved. The earliest land plants to evolve were ...s we see today. Evolution of this growth control mechanism appears to have happened in a series of steps, which this study is able to associate with major stag...Antibody retards growth and induces death in liver cancer cells
...ase of grim prognosis due to the poorly understood mechanism of how the disease originates and spreads. Most patients live only a short time after diagnosis. Based on previous studies showing that some pathways that were previously thought to be active only during fetal liver development, particularly the cl...New use for a cell toxin found to inhibit survival proteins in cancer cells
...mycin inhibitor. This is called a gain of function mechanism and is counterintuitive to the way most drugs work...or the study, 2-Methoxy antimycin reveals a unique mechanism for Bcl-xL inhibition, came from the New Technology Development Fund administered by the Hutchinson ...A stepwise retreat: How immune cells catch pathogens
...ent online issue of PNAS they describe a molecular mechanism that likely underlies the tentacle movement and th...of filopodia retraction and the possible molecular mechanism underlying them could find applications in nanotechnology, says Alexander Rohrbach a former member o...5 OHSU faculty members singled out for honors
...ool of Nursing activities. OCNE is a collaborative mechanism established in response to the states critical nursing shortage to foster a dramatic expansion in the capacity and enrollment of Oregons nursing programs. Through OCNE, students at the states eight community colleges, through a shared curriculum crea...Researchers probe risks, benefits of folic acid fortification
...total amount of folic acid ingested increases, the mechanism that converts folic acid to methyltetrahydrofolate can become saturated. The leftover folic acid in the circulation might have detrimental effects, as it is not a natural form of the vitamin. At a time when many countries are debating whether or no...Aphids make 'chemical weapons' to fight off killer ladybirds
...the entire colony. Unfortunately the nature of the mechanism with the chemical stored in the insects blood and the catalyst stored in its muscles means that in most cases the individual aphid responsible for seeing-off the ladybird predator dies in the process of protecting the colony....Study provides new data about the laws governing embryo development in organisms
...t system parameters and showed that the biological mechanism maintained its functionality in 91% of the cases analyzed. According to Miln and Buceta this study confirms the hypothesis that if this gene network has been maintained across evolution in both vertebrates and insects, it is precisely because it is h...Scientists follow familiar TRAIL to new cancer therapy
... Like c-Myc, sorafenib appears to work through a mechanism that involves repression of TRAIL-induced expression of Mcl-1 and cIAP2. These results also establish the clinical potential for combining TRAIL or other death receptor agonists with an orally bioavailable, low-toxicity multikinase inhibitor, sorafen...Internal clock, external light regulate plant growth
...es called PIF 4 and PIF 5. "It's a nice, elegant mechanism for how these two systems interact," said Julin Maloof, assistant professor of plant biology at UC Davis, who is senior author on the paper. When the seedlings are grown in constant light, most growth occurs in the late afternoon. But when the plan...Double identities lie behind chromosome disorders
...cells contain a control station for monitoring the mechanism that ensures that the correct numbers of chromosom...ow shown that there is an alternative distribution mechanism in female sex cells that cause chromosome disorders. Aberrant chromosomes orientate themselves like ...U-M, Israeli scientists report major advance in search for genes associated with colon cancer
... but several groups are working to close in on the mechanism that might cause these cancers. Gruber is an associate professor of internal medicine and of human genetics in the U-M Medical School, and of epidemiology in the U-M School of Public Health. He directs the Cancer Genetics program in the U-M Compreh...Study identifies a common genetic risk factor for colorectal and prostate cancer
...on notes, We still need to identify the biological mechanism through which these variants are influencing the development of various cancers....... a mouse model reveals increased cell death as the mechanism underpinning kidney degeneration in NPHP. The genetic cause is a mutation in a gene called GLIS2. GLIS2 normally prevents cell death in the adult kidney. It does so by shutting down genes that initiate cell death and that are only required during t...