Tag: "membrane" at biology news
Biologists discover new pathway into plant cells
... in this case, the protein does penetrate the cell membrane
and interacts with chloroplasts, ultimately leading to cell death." The scientists said this mechanism probably will be found in other cells besides wheat, and with other proteins. And while it may lead ultimately to some way to help address this pl...
Researchers develop new method to help find deadly malaria parasite's Achilles heel
...ally jumps out of our paper is the large number of membrane
protein interactions in Plasmodium that are absent in other organisms. While this is potentially good news for fighting malaria, we need to know much more before we start talking about which membrane-protein interactions to target with a new drug."...
Sleeping sickness parasite shows how cells divide their insides
... distribution. Warren studies the Golgi complex, a membrane
compartment in the cytoplasm that delivers newly-made proteins to different membranes in the cell. "Basal bodies in particular and centrosomes in general have been implicated in the biogenesis of a number of membrane-bound organelles," said Warren. "...
JCI table of contents December, 2005
.... The authors show that stabilizing mitochondrial membrane
potential stabilizes the cellular action potential (AP), blunts AP shortening during ischemia, and prevents ventricular arrhythmias during reperfusion. This work could explain ischemia-related arrhythmias and explores the therapeutic potential of a ...
Cancer wasting, muscular dystrophy show common change
...o other proteins associated with dystrophin in the membrane
of muscle cells. These proteins form the dystrophi...DGC is a cluster of proteins that extends from the membrane
into the surrounding tissue and anchors the muscle cell in place. Dystrophin works like a shock abso...
Muscular dystrophy and cancer-associated muscle wasting share dystrophin dysfunction
...tein complex (DGC), a structure in the muscle cell membrane
that is mutated in the muscle wasting disease muscular dystrophy. Progression of cancer is associated with reduction of dystrophin and abnormal regulation of the DGC proteins. Mice lacking dystrophin exhibit enhanced tumor-induced wasting, while tran...
Innovative research set to push boundaries of cancer care
...strategy briefly increases the permeability of the membrane
of tumor cells, allowing the very large plasmid mo...d P-gp, control which molecules can pass through a membrane
(such as the "blood-brain barrier") and are also part of a cellular defense that is associated with ...
Zooming in on the protein-conducting channel
... pore that is perpendicular or lateral to the cell membrane
to feed the new protein either across or into the membrane. For the studies, the Swiss researchers created a complex comprising the PCC from E. coli attached to a ribosome that contained a newly forming protein segment. The ribosome is the massive...
Plants have a double line of defence
...gainst pathogens. PEN2 is an enzyme located in the membrane
of what are called peroxisomes. These are spatially separated cell compartments, in which metabolic reactions often take place that would be dangerous for the organism at any place other than inside the compartments. If a fungus tries to invade a pla...
Nanoparticles, nanoshells, nanotubes: How tiny specks may provide powerful tools against cancer
...t if the lytic peptide has no interaction with the membrane
it is targeting, it cannot kill," Leuschner says. The research group next looked at nude mice mice lacking immune systems that carried xenografts of human breast cancer. In another proof-of-concept study, they found that if a nanoparticle-Hecate c...
Bacteria which sense the Earth's magnetic field
... other magnetosome proteins) is a component of the membrane
that encloses every indivudual magnetite crystal. ...ly the magnetite crystal, but also the surrounding membrane
vesicle, in a resolution never achieved before. Amazingly, the scientists saw a previously unknown f...
Plant gene related to cancer treatment may foster new oncology drugs
... molecules essentially are pulled through the cell membrane
by PGP transport proteins," Murphy said. "It's an energetic process that happens like pulling a rope through something sticky." Both the multi-drug resistant PGPs in people and plants are part of a large family of proteins, called ATP-binding cassett...
Einstein scientists discover how protein crucial for motion is synthesised at the right place in the cell
...lymerizes into long filaments that push the cell's membrane
outward to form protrusions. The team's previous work showed how newly formed actin messenger RNA molecules find their way to the cell's periphery: A protein called ZBP1 binds to the messenger RNA and "escorts" it out of the fibroblast nucleus and i...
Picking particles faster than one at a time
...ibosome, say, which combines protein and RNA, or a membrane
protein that readily falls apart in water and is hard to crystallize -- biologists often turn to cryo-electron microscopy (cryo-EM) to perform single-particle reconstruction. Understanding structure is often the key to devising antibiotics and other...
Purdue biologists clarify how a cellular 'spacecraft' opens its airlock
...n between these minuscule gates - which are called membrane
transport proteins - and the steps by which they u...ne called an ABC protein, which is the part of the membrane
protein that connects it to the interior of the cell. These ABC proteins use the energy to bend the ...
A salty tale: New bacterial genome sequenced from ancient salterns
...ght energy and using it to move protons across the membrane
and out of the cell. In doing so, the protein maintains a balance of ions inside and outside the cell. "It's very unusual to find the two different types of rhodopsin in the same organism," Mongodin says. "S. ruber may have independently evolved one...
Researchers uncover mechanisms of estrogen in promoting cell death in breast cancer
...way. This pathway is controlled by proteins on the membrane
of cell organelles called mitochondria. Estradiol ...ncreased the expression of several proteins on the membrane
of cell mitochondria, led to depolarization of the mitochondrial membrane, and stimulated the releas...
Pall filtration technology verified to remove arsenic from drinking water
... Corporation (NYSE: PLL) announced today that its membrane
filtration technology was granted verification by ...val, such as reverse osmosis and adsorption media, membrane
filtration offers a less costly and long-term solution. It does not require a major upfront capital...
Leibniz Prize winners 2006
...ds explaining the interactions between the various membrane
channels and neurotransmitters involved in these communication processes and to representing the sequence in which this communication takes place. His work is related to the research conducted by Nobel Prize laureate Erwin Neher, and it has advanced ...
Chlamydia parasite lives off our fat
...ed for proteins known to regulate lipid synthesis, membrane
traffic and cell signaling. Now in new research presented Sunday at the 45th Annual Meeting of the American Society for Cell Biology in San Francisco, Yadunanda Kumar and Raphael Valdivia of Duke University Medical Center report that Chlamydia loves ...
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