Tag: "membrane" at biology news

Tracking membranes of rupturing blood cells sheds light on malaria infection

...blood cells. Further experiments involving labeled membrane components showed that there is no membrane fusion during release, but that instead it is likely that a build-up of pressure occurs inside the c...

NIH renews network focused on how genes influence drug responses

...ity in the genes for "gatekeeper" molecules called membrane transporters, which interact with up to a third of the most commonly used prescription drugs. (Kathleen M. Giacomini, Ph.D., University of California, San Francisco) Pharmacogenomic Evaluation of Antihypertensive Responses --$11.1 million...

VCU researchers design new receptor and enhance bioassay to advance drug discovery process

...rs were able to improve upon the currently applied membrane leakage assay used to evaluate specific properties.... "Therefore, we wanted to improve on the existing membrane leakage assay. "The high affinity of this receptor to pyranine, its impermeability to the lipid bil...

Frog peptides block HIV in lab study

...perhaps by inserting themselves into the HIV outer membrane envelope and creating "holes" that cause the virus..."We like to call these peptides WMDs -- weapons of membrane destruction," Unutmaz said. It is curious that the antimicrobial peptides do not harm the T cells at...

Rhythm gene discovered

...rs" on the endoplasmic reticulum, a calcium-filled membrane bag inside each cell. IP3 makes the endoplasmic reticulum release calcium into the cell. Ups and downs in calcium levels control the rhythmic contractions responsible for swallowing, ovulating and pooping in worms. ...

Scientists discover genetic key to growing hardier, more productive plants

... growth hormone, auxin, through the plant's plasma membrane and through the plant's root and shoot systems, resulting in enhanced cell division and growth." All plants contain three proton pumps a master pump, known as the P-type H+-ATPase, that facilitates transport of nutrients in and out of plant cells, a...

Jefferson scientists uncover new clues to how crucial molecular gatekeepers work

...n action potential travels along a nerve, the cell membrane charge changes. The inside of the cell (normally e... the cell's inside becomes negative again, and the membrane returns to its normal resting state. The more recent and controversial theory proposed by Nobel lau...

Researchers find a potential key to human immune suppression in space

...s-Fulford. "It's the infrastructure of the cell, a membrane made of lipid, and maybe without gravity it's not as well-organized as it should be." Human immune suppression in space was first observed in the 1960s and 70s during the Apollo missions conducted by the United States. As the researchers note in thei...

$6.5M nanomedicine center includes Yale engineer

...rters, proteins that control ion motion across the membrane of every living cell. Nanomedicine operates at the biological molecule scale of 100 nanometers or less to cure disease or repair damaged tissues. A nanometer is one-billionth of a meter. The first target for the center will be to design a class of de...

Life in deadly conditions

...aptation strategies. These components are the cell membrane and the proteins that have to function outside the..., the respiratory chain - are embedded in the cell membrane and have to be adapted to the adverse external conditions. Despite a detailed bioinformatic analysis...

UCF researchers to develop water purification system for hurricane relief

...introducing nanoparticles into a mobile integrated membrane system, we can create potable water from a variety of sources," said Seal, who also works with the Advanced Materials Processing and Analysis Center. Taylor, who has conducted water treatment research since 1975, said drinking water could be consiste...

Stem cells' electric abilities might help their safe clinical use

...l ion channels, which are valves in a cell's outer membrane allowing the passage of charged atoms, the basis o...otassium channels are responsible for altering the membrane voltage of cells," says Li. "This in turn is required for the progression of certain cells into the ...

Scientists discover secret behind human red blood cell's amazing flexibility

...Very little is known about how the elements of the membrane skeleton behave when red blood cells deform, and w...en mystified for years by the human red blood cell membrane skeleton, a network of roughly 33,000 protein hexagons that looks like a microscopic geodesic dome. ...

Gene therapy reverses genetic mutation responsible for heart failure in muscular dystrophy

..., or LGMD. In human LGMD, defects in a muscle cell membrane protein known as delta-sarcoglycan lead to severe damage and weakness to muscles, particularly around the hips and shoulders--hence the name "limb girdle"-- as well as in the heart. Like humans, hamsters with this particular delta-sarcoglycan gene de...

Story tips from the Department of Energy's Oak Ridge National Laboratory, October 2005

...liquid vapor then travels through the ground probe membrane and is analyzed by the mass spectrometer (MM1) aboard the FOX vehicles. The probe controls the amount of sample offered to the MM1, preventing sample overloading and resulting in a much more confident identification. When the analysis is complete, th...

Pall Corporation presents approach for speeding vaccine production to Shanghai conference

... higher binding capacity of single-use Mustang TM membrane capsules for large molecule applications compared to conventional resin- or gel-based column chromatography. The process also incorporates the use of disposable prefilters, sterilizing grade capsules and final filters to provide exponential time, cos...

Yale cell biologist, Ira Mellman, one of three Americans honored by EMBO

...r mechanisms that sort, target, and transport cell membrane components to their different and appropriate membrane locations in many different types of cells. He joined the Yale faculty of Cell Biology in 1981 afte...

New discoveries about neuron plasticity linked to learning and memory

...ows that ion channels distributed in the dendritic membrane change during a simulated learning task and that t...els, which are distributed throughout the dendrite membrane and allow the passage of potassium and sodium ions into and out of the neuron, are altered during le...

JCI table of contents November, 2005

... can break the heart Receptors that span the cell membrane seven times (7-transmembrane receptors) typically relay signals from outside the cell by coupling to G proteins inside the cell. Rarely, the signal transduction is G protein independent, but the physiological consequences of this unconventional mech...

Targeted drug delivery achieved with nanoparticle-aptamer bioconjugates

...to RNA aptamers that bind to the prostate specific membrane antigen (PSMA) a well known marker for prostate cancer which is over-expressed on certain prostate epithelial cells. Experimental results described at ECCO 13 show that these bioconjugates successfully and selectively adhered to PSMA-positive prosta...

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(Date:4/16/2014)... store memories improves during childhood, associated with structural ... prefrontal and parietal cortices. New research from UC ... at this crucial time. Eventually, that could give ... transition into and during adolescence and affect memory, ... in the middle of the brain, the hippocampus ...
(Date:4/16/2014)... Dr. Klaus Aktories and Dr. Panagiotis Papatheodorou from the ... the University of Freiburg have discovered the receptor responsible ... perfringens into the cell. The TpeL toxin, which ... that causes gas gangrene and food poisoning. It is ... germs of the genus Clostridium . The toxins ...
(Date:4/15/2014)... 15, 2014, Irvine, Calif. UC Irvine neurobiologists have ... results when transplanted into the brains of mice with ... trial is published in the journal Stem Cells ... shown to work in two different mouse models. ... of dementia, is associated with accumulation of the protein ...
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