Tufts Veterinary School scientists decode Cryptosporidium genome
...t also unravel key biological characteristics that might help explain the difference between the pathogen that infects humans only and C. parvum, which is transmitted between humans and animals." ...Trojan-horse therapy blocks buildup of Alzheimer's plaque
...ween much larger proteins. The researchers said it might also be possible to use this new approach to sabot...ht, said Crabtree, that the Trojan horse technique might be ideal to prevent the formation of toxic amyloid aggregates to prevent Alzheimer's disease. "Isabe...Red wine mist? Resveratrol shows potential effects against COPD, asthma, arthritis
...ogen or glucocorticoid receptor; thus these agents might be beneficial in inflammatory diseases where glucocorticosteroids have proved to be ineffective, such as COPD, steroid-resistant asthma, and arthritis. These compounds may provide candidate molecules for the development of novel anti-inflammatory the...UCLA and Univ. of Utah researchers identify how a hormone regulates iron
...rugs to block hepcidin from binding to ferroportin might help release more iron into the body. Hemochromatosis is the most common genetic disease in the United States according to the Centers for Disease Control. One in 100-200 people have a double mutation of a gene that puts them at risk for developing ...Diabetic damage to eyes, heart, nerves, kidneys may be explained by controversial theory
...the potential to produce much more damage than you might expect if you looked at either one independently," Williamson explains. Scientists have known for some time that diabetes increases transformation of NAD to NADH by boosting cells' consumption of glucose through a process known as the sorbit...Scientists closing in on nerve proteins' contributions to memory and hearing loss
...ientists have begun amassing evidence that Nrg-ICD might be as important or even more important than Nrg-ECD. "In a comparison of the frog and human genes, we earlier showed that Nrg-ICD was 87 percent identical between the two species," says Bao, who is first author of the new study. "When part of a pr...Is the zebra fish leading us to new therapies?
... of Leuven) asked themselves whether blood vessels might perhaps use the same signals as nerve cells. To answer this question, the researchers called on the small, translucid zebra fish. The great advantages of using zebra fish instead of mice are that zebra fish grow and multiply very rapidly and - becau...Stress impairs thinking via mania-linked enzyme
...Since PKC inhibitors could act more directly, they might quench symptoms more quickly. Patients could carry PKC inhibitors and take them preventively, as soon as they sense a manic episode coming on." Clinical trials of a PKC inhibitor, the anti-cancer drug tamoxifen, are currently underway in bipolar diso...Human embryonic stem cells promising for replacement of blood supply
...urce of new blood supply free of any viruses. They might also be a source for bone marrow transplants, especially for those patients who do not otherwise have an appropriately matched donor." This process is also significant because the blood cells were developed without the use of animal serum, which was ...DASH diet may do more than lower blood pressure
... are partly attributable to the phytochemicals and might extend beyond cardiovascular disease reduction," according to registered dietitian and lead researcher Marlene M. Most. Phytochemicals are substances that plants naturally produce to protect themselves against viruses, bacteria, and fungi. And, they ...Ethical paradigm: Relating embryonic stem cell use to organ donation
...lowed by . The authors propose a similar mechanism might be used for embryonic cells. At this stage, however, no definition for death has been defined for unformed humans. The authors highlight the point that many embryos created for in vitro fertilization are not used because they are unable to properly ...Gene that blocks free radical damage protects against emphysema
...oxidant and cell-protective genes in the lung that might function together to protect the lung from cigarette smoke-induced emphysema. These data suggest that the Nrf2 pathway provides protection from emphysema by turning on antioxidants and suppressing inflammation and cell death in the lung.......reported the discovery of a coral-like animal that might be a candidate for parenthood (Xiao, S., Yuan, X.,...looking for more evidence, but if that is true, it might link the embryo fossils to the tubular coral-like animal." The researchers will slice open a hatched...Plentiful fossils of dinosaur contemporary allow population study
...vic region that about 40 percent of them have. One might be female and one male, Casey said. "We found no s...etermine what effects the exceptional preservation might have on other Tany studies. Casey's bone measurements also note when bones were missing, "so all th...JCI table of contents November 1, 2004
...oxidant and cell-protective genes in the lung that might function together to protect the lung from cigaret...lowed by . The authors propose a similar mechanism might be used for embryonic cells. At this stage, however, no definition for death has been defined for u...Sleeping, waking, ... and glucose homeostasis
...havioral effect, whereby the disruption of the SCN might alter our feeling of being well fed-that is, being...ehavioral effect that ablation of the hypothalamus might have caused. It's possible, therefore, that besides what we eat, our internal circadian clock could ...Economics and ecology combine at UGA in NSF-funded study of evolutionary game theory
...eferred economic method for studying how two firms might compete with one another in the marketplace," said Keenan. "There is, however, a newer branch, called evolutionary game theory, which is useful in biology." "Our work will apply game theory to the conflict between that most rational of creatures hu...Initial sensor for p53 tumor-suppressing pathway identified
... a DNA break, you can imagine that the nucleosomes might unravel and the stacking of the nucleosomes fall apart, exposing the site that 53BP1 recognizes," Halazonetis says. "This is the model we are proposing for how cells sense the presence of DNA breaks to activate the p53 pathway."...Researchers grow sperm stem cells in laboratory cultures
...ontains the spermatogonial stem cells, researchers might also be able to induce the spermatogonial cells to...iseased or injured tissue. The replacement tissue might be used to help patients with spinal cord injury, or disorders like Parkinson's disease or heart dis......these proteins look, we began to ask whether there might be a common ancestor or whether proteins might evolve using similar kinds of rules that whole organisms use to evolve," Ealick reasons. In fact, hi...