Tag: "modifies" at biology news

UF scientist: 'Brain' in a dish acts as autopilot, living computer

...ifts randomly. And as the data comes in, it slowly modifies the (neural) network so over time, the network gradually learns to fly the aircraft." Although the brain currently is able to control the pitch and roll of the simulated aircraft in weather conditions ranging from blue skies to stormy, hurricane-fo...

JCI table of contents, November 15 2004

...ation by which an environmental trigger like aging modifies genetic susceptibility to type 2 diabetes. In an accompanying commentary, Alan R. Shuldiner and John C. McLenithan from the University of Maryland School of Medicine discuss these results and how aging, diet, exercise, and other fac...

Aging affects susceptibility to type 2 diabetes

...ation by which an environmental trigger like aging modifies genetic susceptibility to type 2 diabetes. In an accompanying commentary, Alan R. Shuldiner and John C. McLenithan from the University of Maryland School of Medicine discuss these results and how aging, diet, exercise, and other factors can affect...

University of Texas at Austin researchers identify drug-tolerance mechanism in flies

...permits potassium to enter the cells in a way that modifies electrical signaling. The researchers think that when a drug causes nerve cells to fire too rapidly, slo levels are decreased to produce fewer portals and dampen the drug's effect. Having the slo gene instead become more active when the nervous s...

Stowers researcher publishes DNA double-strand break repair discovery in Science

...nizes phospho-H2A.X/v when present on DNA. It then modifies the phospho-histone by acetylating it, which facilitates its removal from DNA. In a second step, the dTip60 complex removes phospho-H2A.X/v and replaces it with an unmodified form of the histone. Taken together, Dr. Kusch's findings show that the dTi...

Ocean colour satellites guide research ship through South Pacific's watery desert

...h the influence of chlorophyll and other pigments, modifies this initial colour towards blue-green, then green and finally brownish for increasing chlorophyll concentration. Phytoplankton play a vital role in the life of the ocean, Claustre explained: "These vegetal organisms form the first link in ...

The simple truth: Animal development not as complicated as it seems

...mechanisms in the hope of unraveling how evolution modifies more complicated and, therefore, more interesting traits like body size, aging or behavior. Azevedo and his colleagues constructed an algorithm to contrast the developmental complexity of different organisms based on their sequences of cell divisio...

Surprising study reveals how cancer-causing protein activates

...ecade. One known trigger is phosphorylation, which modifies some of the tyro-sine and serine amino acids that ...rigger: acetylation, another chemical process that modifies amino acids, such as lysine. Chin said this finding might explain why drugs that only block STAT3 ph...

Ingestion of afterbirth appears to promote maternal behavior in mammals

... is the hypothesis that afterbirth, when ingested, modifies specific opioid-receptor systems in those two brain regions," he says. "We think that, in particular, POEF optimizes the onset of maternal behavior by enhancing the facilitating effect of opioids in the ventral tegmental area and attenuating t...

Scientists find missing enzyme for tuberculosis iron scavenging pathway

...ins Dr. Baker. "The N-acetyltransferase chemically modifies the sugar amino group by transferring an acetyl group to it. This inactivates the antibiotic because it can no longer fit into its target." However, in vitro biochemical assays have failed to demonstrate aminoglycoside N-acetyltransferase activity in...

Study finds enzyme activity promotes rare form of leukemia, offers potential target for new drugs

...lled." Zhang investigates a group of enzymes that modifies five core histone proteins forming the molecular scaffold that helps organize DNA within the nucleus of every cell. Histone modifications affect gene activity and include methylation, in which a methyl component is attached to the histone protein. "...

Scientists take aim at virulent bacteria by decoding machinery of key control enzyme

...y bacteria. Each time the bacteria reproduce, Dam modifies the A (adenine) nucleotide in the DNA sequence GATC through a chemical reaction known as methylation. Methylation is a biological process used to tag a variety of molecules, including DNA, and is important in cellular processes such as regulating ge...

JCI table of contents June 1, 2005

...alassemia." TITLE: Heme-regulated eIF2alpha kinase modifies the phenotypic severity of murine models of erythropoietic protoporphyria and beta-thalassemia AUTHOR CONTACT: Jane-Jane Chen Massachusetts Institute of Technology, Cambridge, MA USA Phone: 617-253-9674; Fax: 617-253-3459; E-mail: j-jchen@mit.edu V...

Marshfield Clinic researchers launch study of environmental causes of Alzheimer's disease

...er's disease. A second gene, Cytochrome P46, which modifies cholesterol, may be associated with Alzheimer's disease and the way the body removes cholesterol from the brain. The other two genes, Oxidized LDL receptor 1 and Angiotensin 1-converting enzyme, are tied to the way the brain cells bind to APOE and re...

Enzyme's newly discovered role may make it target for arthritis treatment

... surface can send a signal back into the cell that modifies the cell's behavior, allowing it to do things like secrete inflammatory factors," Pham explains. "The proteases' ability to affect integrin rearrangement is dependent on their catalytic activity, and that's an ability that can be taken away from them...

Study separates behavioral and physiological mechanisms in testosterone mediated trade-offs

...wild animals. One possibility is that testosterone modifies behavior and increases exposure to infective parasite larvae. An alternative mechanism is related to the physiological actions of testosterone, which cause increased susceptibility to parasites. In an article in the August 2005 issue of The America...

Spiders help scientists discover how muscles relax

...dehydration and staining of a tissue sample, which modifies the structure of the specimen and distorts its shape. Cryo-electron microscopy avoids these problems by rapidly freezing the sample. Using the new technique, the researchers were able to visualize the muscle tissue in a form closer to its structure i...

JCI table of contents September 1, 2005

...rP is a potent endogenous bone anabolic agent that modifies the therapeutic efficacy of administered PTH 1-34 AUTHOR CONTACT : Andrew Karaplis McGill University, Montreal, Canada Phone: 51 4340-8222; E-mail: akarapli@ldi.jgh.mcgill.ca View the PDF of this article at : https://www.the-jci.org/article.ph...

Take two!

...sm in altered light conditions. STN8 fundamentally modifies photosystem II, in which it phosphorylates proteins. For a long time, this phosphorylation was considered important for the replacement of defective proteins in the photosystem II. The researchers were able to show, however, that the phosphorylation ...

How Rickettsial pathogens break into cells

...ts, and that the protein modifier called ubiquitin modifies Ku70 as soon as the bacteria interact with it. This step is critical for cell entry. "Whether other Rickettsia and other pathogens use Ku70 as a receptor is still unknown," Cossart said....

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Breaking Biology News(10 mins):Sandata Announces Case Study with Quality Care Services, Inc. 2Two-faced gene: SIRT6 prevents some cancers but promotes sun-induced skin cancer 2
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