Unravelling new complexity in the genome
...erated provides a valuable basis for understanding molecular mechanisms by which genes can function differently in different parts of the body. Blencowe attributes these new findings in part to the power of a new tool that he, together with his colleagues including Profs. Brendan Frey (Department of Electric...Diverse genetic abnormalities lead to NF-κB activation in multiple myeloma
...journal Cancer Cell, provides new insight into the molecular mechanisms that underlie aberrant NF-κB activ...een implicated in various types of cancer, but the molecular mechanisms involved are not well understood. Two separate research groups used a variety of sophisti...... the site of injection) in order to understand the molecular mechanisms underlying this invasive behavior. They identified the neurotrophin receptor p75NTR, which normally functions during development to induce neurite outgrowth and promote neuronal cell death, as an important regulator of glioma invasion. The...Doernbecher Children's Hospital scientist earns coveted Javits award
...(NINDS) for his pioneering workin the cellular and molecular cause(s) of brain injury in prematureinfants. NINDS is a branch of the National Institutes of Health. "I am thrilled the NINDS continues to recognize the potential of theunique research models we have developed - some of which are not usedanywhere ...High blood pressure, low energy -- a recipe for heart failure
...pertensive patients. The researchers assert that a molecular factor involved in maintaining the heart's energy ...approaches to prevent or treat heart failure. The molecular factor, a protein called estrogen-related receptor alpha (ERR alpha), helps the heart keep up with e...Abnormal fat metabolism underlies heart problems in diabetic patients
...ogy and professor of medicine, of chemistry and of molecular biology and pharmacology. "Unfortunately, this change in metabolism distorts the lipid composition of cell membranes causing abnormal physical properties and cellular dysfunction." The important lipid that the researchers found to be decreased in dia...New textbook illuminates the close links between evolutionary and molecular biology
..., combines the contemporary fields of genetics and molecular biology with traditional evolutionary theories to ... breadth. The branches of biology concerned with molecular events and evolutionary principles have developed independently of one another. But with recent bre...ESF EURYI award winner aims to stop cancer cells reading their own DNA
...ng new line in anti-cancer therapy by blocking the molecular motors involved in copying genetic information dur... to stop tumor development by interfering with the molecular motors that copy DNA during cell division. This will cut off the genetic information flow that tumou...OHSU turns mouse into factory for human liver cells
...aid study leader Markus Grompe, M.D., professor of molecular and medical genetics, and pediatrics, OHSU School of Medicine. "In terms of fostering research, this will be great for malaria, this will be great for hepatitis, this will be great for liver stem cells, this will be great for gene therapy. It will ...Gilbert Foundation and American Fed for Aging Research award grants on Alzheimer's disease
...roteins by manipulating a class of proteins called molecular chaperones. These chaperones help in the processing of proteins within neurons and may represent an entirely novel class of candidates for therapeutic development in Alzheimers research. Isabella A. Graef, M.D., Assistant Professor, Stanford Univ...A unique arrangement for egg cell division
...iology Laboratory (EMBL) have now revealed how the molecular machinery functions that is responsible for chromo...ght in by the sperm cell during fertilisation. The molecular apparatus that makes sure that the egg ends up with the correct number of chromosomes is a bipolar s...JCI table of contents: Aug. 9, 2007
EDITOR'S PICK: New molecular regulators of hyperthyroidism and goiter The th...hey eat more calories than they burn. However, the molecular pathways that control feeding behavior and cellular energy expenditure are highly complex and not co...Proteaceae spread by continental drift and transoceanic dispersal
...anges. Barker et al. apply a technique known as molecular dating to DNA sequences from over 40 representativ...ank Rutschmann in Zurich, who had the expertise on molecular dating, and Herv Sauquet, a postdoc at the Royal Botanic Gardens, Kew, United Kingdom with an extens...European Science Foundation's Forward Look reaches out beyond the endless frontiers
...ted technologies, e.g. closing the gap between the molecular and the cellular technologies and the clinical diagnostic nanotechnologies Recommendations on organization and funding of Nanomedicine-related research activities Proactive risk assessment for nanomaterials needed Recommendations o...Brain blood flow gives clues to treating depression
RESTON, Va.The usefulness of established molecular imaging/nuclear medicine approaches in identifying...PECT (single photon emission computed tomography)a molecular imaging/nuclear medicine procedure in which injected radiotracers are utilized to produce three-dime...Cardio exercise benefits in male vs. female hearts
...ctors for heart diseases are likewise unequal. The molecular mechanisms responsible for these differences are s...he RNA of each mouse to look at any changes at the molecular level. Results The researchers found that the female mice: showed a much higher level of e...Preclinical study links gene to brain aneurysm formation
... that the NOS-3 gene is just one step in a complex molecular pathway that links flow-dependent vascular remodel...red to suppress (knock out) one of three genes and molecular pathways associated with vascular disease: inducible nitric oxide synthase (NOS-2), endothelial nitr......rch team led by John Tower, associate professor of molecular and computational biology at USC, compared normal fruit flies to ones kept in an axenic (bacteria-free) environment. The surprise was that the flies grown under axenic conditions and the normal flies had the same life span, Tower said. The exper......ists led byMagnus Nordborg, associate professor of molecular and computational biologyat the University of Sout...on, said ChrisToomajian, USC research associate in molecular and computational biology andco-author of two new papers on A. thaliana in Science Express and Natur......ding contributions to research in biochemistry and molecular biology. Alexandra C. Newton (University of C... Lipids. Newton has worked for over two decades on molecular aspects of lipid signaling, and as a result has been able to elucidate the molecular controls that r...