New approach to pulmonary hypertension shows promise
...cellular functions by regulating the expression of multiple genes. It is normally activated in important health-maintaining functions, such as the regulation of immune cells and the development of the heart. However, it causes havoc when it is activated "inappropriately", such as in the case of pulmonary hype...Personalized approach to ovarian stimulation achieves high ART pregnancy rates
...ecialists determine starting doses so as to induce multiple follicle development based upon some of the characteristics used to develop our model, other tests of ovarian reserve, and their previous clinical experience. We hope that this research will represent a move towards an evidence-based approach to the ...Loss of cell's 'antenna' linked to cancer's development
...ese proteins in cancer affect cellular response to multiple signaling pathways, rather like a chain reaction highway accident. Clinical Application The research has significant implications for the understanding and treatment of cancer. The experiments leading to the new paper showed that small-molecul...Pairing nanoparticles with proteins
... Toward that end, Hu and Hainfeld's group attached multiple viral proteins to the gold nanoparticles. Such constructs should have increased binding affinity for target cells and their larger size should extend blood residence time for improved drug delivery. In another application, this new research showed ......sible, but Wells points out that consensus between multiple stakeholders, while acceptable at a political leve...," he explains, "Rather, it creeps upon us through multiple small steps - each one justified by 'necessity'." "Unless we are able to construct rapid and effec...Desertification: UN experts prescribe global policy overhaul to avoid looming mass migrations
...nsparency and accountability, the participation of multiple actors, information sharing, measurable results, and follow-up systems; Better educate local populations and policymakers, many of whom lack adequate awareness of the fragility of their natural resource base and, in some places, fail to understand fu...Cord blood may preserve insulin levels in children with type 1 diabetes
...type 1 diabetes. We probably need to go at it with multiple drugs to attack the various facets of the disease. Curing type 1 diabetes may require a similar approach to treating AIDS or cancer. The care of patients with these complex diseases did not markedly improve until combination therapies were administer...Weizmann scientists discover a new line of communication between nervous system cells
In a host of neurological diseases, including multiple sclerosis (MS) and several neuropathies, the protective covering surrounding the nerves an insulating material called myelin is damaged. Scientists at the Weizmann Institute of Science have now discovered an important new line of communication bet...American Chemical Society's Weekly PressPac -- June 20, 2007
...nd, captrolactam, and could be recycled and reused multiple times. This is the first example of the use of ionic liquids for effective depolymerization of polymeric materials and will open a new field in ionic liquid chemistry as well as plastic recycling, the report states. ARTICLE #2 FOR IMMEDIATE RELEASE...UGR researchers design an alternative to blood test to detect drugs in the body
...luid. The importance of his research lies in the multiple advantages of this fluid with regard to the others. Pericardial fluid is plasma ultrafiltered from the serous vessel surrounding the heart, a watertight compartment separated from blood. Blood analysis usually presents a problem: matrix interferences...New tumor markers -- 'Spot the differences'
...sed microarrays or DNA-chips, a technique used for multiple analyses. It allows the detection and quantification of messages sent by thousands of genes. We analysed biopsies of PC as well as samples of healthy pancreas. The RNA (thousands of messages sent by cells) from each sample was extracted and fluoresce...St. Jude shows gene test not needed if cancer drug given in low doses
...e cancer drug irinotecan is given in low doses for multiple days, it eliminates the need to delay treatment to perform costly genetic testing that determines if the patient is at risk for serious treatment side effects, such as neutropenia. Neutropenia is an abnormal reduction in the numbers of immune cells, ...NJIT professor says certain home shapes and roofs hold up best in hurricane
...s found to have reduced wind loads. Roofs with multiple slopes such as a hip roof (4 slopes) perform better under wind forces than gable roofs (2 slopes). Gable roofs are generally more common because they are cheaper to build. A 30-degree roof slope has the best results. Wind forces on a roof tend to...Study identifies 5 genetic themes key to keeping stem cells in a primitive, flexible state
...at they can become: more of themselves, as well as multiple different specialized cell types. But as genetic techniques have become increasingly powerful, many scientists have sought a more molecular definition of stem cells, based on the genes they express. Now, a team of Canadian scientists has identifie...Inflammation is at the origin and progression of diseases such as diabetes or cancer
... arthritis, inflammatory bowel disease, psoriasis, multiple sclerosis, Alzheimers disease and, most recently, type 2 diabetes and cancer, are diseases that have been associated with chronic inflammation. Carme Caelles, researcher at IRB Barcelona and co-organiser of the conference, explains that until recentl......expensive because they require researchers to make multiple manipulations in mouse embryonic stem cells, which...00,000 times better. That is important, because multiple molecular steps are needed for a mouse to develop a human cancer and such mice are used to learn ho...Gene responsible for common hearing loss identified for first time
...hat this remained significant after correcting for multiple testing. Analysis of a large French group showed the same association. Combining the data from both groups with a common odds ratio gave a very significant result, from which we were able to conclude that we were the first to identify a gene that ...Children born after PGD as healthy as those born after conventional IVF treatment
... the perinatal death rate is higher, especially in multiple pregnancies, then in IVF and ICSi children. We need to further investigate these perinatal death rates, says Professor Liebaers, but we were encouraged to find that the major malformation rate was only 3.6%, or no higher than that which is found in ...UD awarded $11M for osteoarthritis research and unique mentoring program for women scientists
...lection of people to address osteoarthritis across multiple levels, which is what translational medicine is all about, Buchanan said. We have people who can look at the proteins that are important to the healing of cartilage, for example, to people who can create biomechanical models showing the movement of...University of Pittsburgh School of Medicine researchers develop 'off-the-shelf' vascular grafts
...e in very limited supply, as many patients require multiple grafts. Thus, there is an ongoing search for the ideal small-caliber arterial substitute for revascularization procedures. The University of Pittsburgh team, led by David A. Vorp, Ph.D., associate professor of surgery and bioengineering and a facul...