Dietary supplement a potential treatment for Canavan disease
...cumulated NAA and the cause for the destruction of myelin is not known. In this new research, myelin lipid synthesis was studied in the mouse model of Canavan disease. The objective was to test the hyp...Stem cell treatment improves mobility after spinal cord injury
...cal conduction in the central nervous system. When myelin is stripped away through disease or injury, sensor... In the rats treated seven days after the injury, myelin tissue formed as the oligodendrocyte cells wrapped around damaged neurons in the spinal cord. Within...... in mammals known to regulate nerve insulation and myelin formation in the central and peripheral nervous system. All commonly target RNA, shooting the messenger rather silencing the message at its source (the DNA), as many other regulatory proteins do. This may give them a relatively quick response time, h...Important brain finding results from boy's rare, fatal disease
...strocytes are more important in the maintenance of myelin than was previously thought," says Powers, who notes that others have noticed abnormalities in the astrocytes of patients with the disease. In addition to Proschel, Torres, Mayer-Proschel, and Noble, authors of the paper include neurologist Jorg Die...Alcohol's effects on gene expression in the central nervous system
...gnaling (which modulates nerve cell activity), and myelin structure (which is needed for communication between nerve cells)," said McBride. "Gene expression profiling has also been used to identify chromosomes and chromosomal regions that influence alcohol drinking and response to alcohol." Intracranial...New component of the 'brakes' on nerve regeneration found
...s' response to the "braking" molecules produced by myelin and encouraged neuron growth. "Given the limited e...re than one TNF receptor member may be involved in myelin inhibition adds a new level of complexity to designing therapeutic strategies for treating CNS injur...Gene with broad role also causes prevalent, inherited nerve disorder
...impulse slows due to degradation of the protective myelin sheath that normally covers nerve axons, Zchner explained. Axons are the cable-like extension of the neuron from the cell body in the spinal cord to the juncture, or synapse, between the nerve ending and muscle. Demyelinated axons conduct nerve impul...JCI table of contents, 3 January 2005
...dies such as IgG or IgA, correlates with levels of myelin basic protein in the cerebrospinal fluid, an index of myelin destruction. In the January 3 issue of the Journal of Clinical Investigation, Luisa Maria Villar and...Stem cells may hold promise as multiple sclerosis cure
...egions as early as one day after injection. As the myelin was repaired, symptoms in the mice improved. The ability to monitor the migration of the transplanted cells is vital if the treatment is going to be adapted to MS patients. "The development if this MRI-based method to track labeled cells non-...UCI researchers use human embryonic stem cells to aid spinal cord injury repair
...odendrocytes, which are the building blocks of the myelin tissue that wraps around and insulates nerve fiber...al cords of mice genetically engineered to have no myelin tissue. After transplantation into mice, the early-stage cells formed into full-grown oligodendrocyt...