Function of nuclear ribosomal proteins
...roviding additional insight into the long-standing mystery as to why components of the translation machinery exist in the cell nucleus. Dr. Sun and colleagues found that in the nuclei of Drosophila cells, ribosomal proteins are associated with linker histone H1 protein on chromatin. Depletion of the ribosoma...UCI researcher named Pew Scholar
... work in Tsai's laboratory focuses on decoding the mystery of polyketide synthases (PKSs), the enzymes that produce polyketide natural products. Polyketides are known to have more than a hundred functions in nature, from making flowers colorful to acting as defense mechanisms for microorganisms. Polyketides ...Researchers discover which organs in Antarctic fish produce antifreeze
...es report they've solved the ensuing, long-running mystery of where these AFGPs, which allow the fish to survive in icy waters, are produced. "Ever since the discovery of these antifreeze proteins, it was assumed they had to be produced in the liver, since the vertebrate liver is well known as a source of se...Early bird caught the fish: Fossils depict aquatic origins of birds 115 million years ago
... descendents of birds like Gansus. What remains a mystery for now, according to the researchers, is how the amphibious lifestyle of birds like Gansus helped enable them to survive the cataclysmic end of the dinosaurs 65 million years ago....Calorie restriction may prevent Alzheimer's through promotion of longevity program in the brain
...nctions. We hope these findings further unlock the mystery of Alzheimer's and bring hope to the millions of Americans suffering from this disease." Alzheimer's Disease is a rapidly growing public health concern with potentially devastating effects. An estimated 4.5 million Americans have Alzheimer's Disease...Gene discovery opens door to tackling disease
...treatments for the cancers. "If we can unravel the mystery of how SLIRP works to turn down the hormone action in cancer cells we could potentially develop so-called 'smart' drugs that zoom in on the gene," he said. "The benefit is that 'smart' drugs can mean fewer nasty side effects for patients as they targ...Bacteria have their own immune system protecting against outside DNA
..., the building blocks of DNA. "It has been a great mystery why disease-causing genes of bacteria usually contain more adenine and thymine," said Michael McClelland, professor and director of the Molecular Biology Program at the Kimmel Cancer Center. "Now we know this is because such sequences are easier to r...Ritalin packs punch by elevating norepinephrine, suppressing nerve signal transmissions
...herapeutic effects. Researchers want to unlock the mystery of why the drug has the paradoxical effect of decreasing hyperactive behavior and increasing the ability to focus, even though it is a stimulant, said Barry Waterhouse, the study's senior author. "We're developing a series of behavioral and electroph...U-M scientists target key cells and signals that trigger pulmonary fibrosis
...a first step, but an important one, in solving the mystery of this disease. Right now, continued research is the only hope we can offer IPF patients."...How satellite tracking revealed the migratory mysteries of endangered Atlantic loggerhead turtles
...he animal kingdom and they have largely remained a mystery until now. An international team of scientists led by the University of Exeter have uncovered the migratory secrets of endangered loggerhead turtles in West Africa and the results could have huge implications for strategies to protect them. In a pape...Protein connections: A network to understand disease
... the same concept provides clues to unraveling the mystery of how different mutations in different genes can cause diseases with very similar characteristics. In a paper in today's edition of the journal Cell, scientists from Baylor College of Medicine and Harvard Medical School describe a network of protein...ACS weekly press package — May 1st, 2006
...roduct. Scientists are trying to solve a corollary mystery inbiology: What turns a sperm's head and attracts it to an egg for theencounter that results in fertilization? Sperm are notorious for turningtheir microscopic heads and changing directions during their journey towardthe egg. Research shows that spe......d how Prozac promotes their existence, have been a mystery until now. By profiling the telltale marker proteins produced by different kinds of cells in the brains of adult mice, the researchers first defined discrete steps in the complex process, called neurogenesis, that converts unspecialized stem cells in...Knowledge of dendritic cells branches out
...arrow. Exactly how that process happens has been a mystery until now. Using a mouse model, PhD student Shalin Naik, group leader Professor Ken Shortman and a team of colleagues at The Walter and Eliza Hall Institute have discovered the different " precursors " that produce DC. In doing so, they have also de...Scientists solve 30-year-old mystery of mutant mouse's kidney woes
...n infants have located the source of a 30-year-old mystery mutation that causes similar problems in a mouse line. Scientists have known of the mouse line's naturally occurring mutation since the early 1970s. Researchers at Washington University School of Medicine in St. Louis are the first to identify the m...Found in 20 percent of people of African descent: MUHC describes gene that shuts down immune system
...other ethnicities around 60,000 years ago. "It's a mystery why only African populations retained this enzyme," says Dr. Maya Saleh, a medical scientist in the Critical Care Division at the MUHC and assistant professor in the Department of Medicine at McGill University. "It's possible that in Africa the prote...Insects that produce males from unfertilized eggs reveal a surprising cellular feat
...arthenogenesis) remains a mysterious process. One mystery has been the origin of the centrosome, an essential cellular component that is ordinarily derived from the sperm after fertilization. A new study led by researchers at the University of California, Santa Cruz, describes a remarkable process by which ...Diabetes and cancer: Alpha connection
...L Centre for Diabetes & Endocrinology to solve the mystery and yield important information for planned clinical trials with PI3K inhibitors. The study showed that p110 alpha controls the action of insulin and other key hormonal signals that play roles in growth, diabetes and obesity. p110 alpha is frequentl...Possible brain hormone may unlock mystery of hibernation
...le hibernation hormone in the brain may unlock the mystery behind the dormant state, researchers reported in the April 7, 2006 issue of Cell. Hibernation allows animals from bears to rodents to survive unscathed--in a state of suspended animation--under the harshest of winter conditions. If the findings in c......d 30 percent sense short wave length. It's been a mystery how you generate a random pattern like that and still have that ratio." Using the tools that the Duncan laboratory provided, Desplan's group mapped the regulatory region in the spineless gene that drives the random pattern mechanism. "Nobody knew w...