OHSU turns mouse into factory for human liver cells
...spun it off into a Portland-based start-up company named Yecuris through the university's Springboard Program. "Yecuris is a viable start-up company based on significant developments at OHSU," Pradhan said. "The products developed by Yecuris have the potential to ease one of the bottlenecks in drug devel......ed mice that carry a promising candidate reporter named ferritin, which could circumvent these problems. Ferritin works by sequestering iron from cells. When it is overexpressed, iron uptake increases, causing signal changes in the surrounding environment that can be detected by MRI, without the need to a...CTRC enrolls first patients in novel phase II study for sarcoma -- living virus destroys cancer cell
...ovirus is unable to reproduce because of an enzyme named PKR. The enzyme is suppressed in cancer cells, and therefore the reovirus can replicate in the cancer cell and kill it. REOLYSIN typifies the true targeted therapy approach that seeks to use fundamental differences between cancer and normal cells ...Fruit fly gene from 'out of nowhere' is discovered
...new functional genes as well. The hydra gene is named after the Greek mythological beast that had a hound's body and nine snakeheads, because it has nine duplicated first exons (sections of the gene that contain protein-coding information). Each of these exons may serve as alternative starting positions...Rise of dinosaurs in Late Triassic more gradual than once thought
...of a new dinosaur predecessor the researchers have named Dromomeron romeri, are described in a cover story in the July 20 issue of Science. "Up to now, paleontologists have thought that dinosaur precursors disappeared long before the dinosaurs appeared, that their ancestors probably were out-competed and...Protein pulling -- Learning how proteins fold by pulling them apart
...periments were conducted on one piece of a protein named Titin. The Titin piece, dubbed I27, contains 89 amino acids. Harris suspended thousands of intact, folded I27s in a dilute saline solution and let the solution sit long enough for the proteins to become stuck to the bottom of the sample dish. The nee...New proteomics research promises to revolutionize biomedical discovery
...e it. We succeeded in finding the enzyme, which we named MePCE, as an interaction partner of another cellular protein it regulates. Many other important proteins have been uncovered in this analysis and their precise roles in cell function will be published in the coming months and years. Defining the ma...Fedoroff, of Penn State, to receive National Medal of Science
...the Santa Fe Institute, is one of eight scientists named today by President Bush to receive the 2006 National Medal of Science, the nation's highest award for lifetime achievement in scientific research. The honorees will receive medals at a White House ceremony on 27 July 2007. The National Medal of Sc...Tips from the Journals of the American Society for Microbiology
...searchers identified a novel parasiticidal peptide named longicin from the tick species Haemaphysalis longicornis and tested its ability to inhibit infection. It showed a remarkable ability to inhibit the blood stage of equine Babesia equi by killing the parasites and resulted in reduction of parasitemia ...Researchers witness natural selection at work in dramatic comeback of male butterflies
...o-called Red Queen Principle, an evolutionary term named after a scene in Lewis Carroll's famous book, "Through the Looking-Glass," in which the characters Alice and the Red Queen run faster and faster at the top of a hill, only to find that they remain in the same place. "In essence, organisms must evol...Decorated UH professor to help choose nation's top scientists
...he National Medal of Science. Chu, who in 1990 was named Best Researcher in the United States by U.S. News and World Report magazine, will serve on the Presidents Committee on the National Medal of Science through 2009. He received the award in 1988 for his work on high temperature superconductivity, makin......the new deep underground research facility will be named the Sanford Underground Science and Engineering Laboratory (SUSEL). Governor Mike Rounds of South Dakota, a strong supporter of the effort to convert Homestake into a research facility, released a statement in response to the NSF announcement whic...New gene mutation identified in common type of dementia
... researchers discovered a new mutation in the gene named progranulin in an extended family in southern Italy. The genealogy of this family has been reconstructed for 15 generations, going back to the 16th century; 36 family members have had frontotemporal dementia. For this study, DNA tests were conducted ...Chronic fatigue -- clues in the blood
...s the Dubbo Infection Outcomes Study. The study is named after the NSW town in which the work was conducted. The team studied the expression of 30,000 genes in the blood, testing each of the 15 individuals between four and five times over a 12-month period. The team was able to narrow its findings to the...Science earns top honor from Spain's Crown Prince
The journal Science was named 4 July to receive one of the world's most prestigious awards from Spain's Crown Prince, recognizing excellence in science communications. The Prince of Asturias Foundation, formed in 1980 under the presidency of His Royal Highness, heir to the thro...M. D. Anderson team identifies new oncogene for brain cancer
...Ras leads to development of astrocytomas a glioma named for the star-like shape of its constituent cells. A combination of K-Ras and a third gene, Akt, previously had been shown to develop astrocytomas. Activation of Akt fuels cell growth and survival. None of the three genes caused brain cancer format...Damon Runyon names new class of rising stars in cancer research
... NY -- The Damon Runyon Cancer Research Foundation named 18 new Damon Runyon Fellows at its May 2007 Scientific Advisory Committee review. The recipients of this prestigious, three-year award are outstanding postdoctoral scientists conducting basic and translational cancer research in the laboratories of ......oratory in Selangor, Malaysia. The new virus was named Melaka after the location in Malaysia where it was...first isolated in humans in the early 1950s and so named because they were not associated with any known disease. According to the leader of the CSIRO team...Nobel scientists Craig Mello and John Mather to speak on origins of life and universe
...02) 707-2692. Speakers John Mather, recently named Chief Scientist at NASA, is an astrophysicist in the Observational Cosmology Laboratory at Goddard Space Flight Center and leads the James Webb Space Telescope science team. He served as project scientist for NASA's Cosmic Background Explorer (COBE) ......hromosome in a second mouse, which also has a gene named Cre in its cells. When the mice are bred, an offsp...nation with a transposon or so-called jumping gene named piggyBac, which comes from a moth. They used piggyBac to insert pieces of loxP DNA randomly into num...