Use your brain, halve your risk of dementia
...time, you lessen the risk of Alzheimer's and other neurodegenerative diseases." The key conclusion is that individuals with high brain reserve have a 46 percent decreased risk of dementia, compared to those with low brain reserve. All the studies assessed agreed that mentally stimulating leisure activities, even in l...Mad-cow culprit maintains stem cells
...tists have found that the same protein that causes neurodegenerative conditions such as bovine spongiform encephalopath...nimals were incapable of contracting prion-related neurodegenerative disease when infected. Researchers knew then that PrP was necessary for mad-cow type diseases; any o...Study using new imaging technology detects subtle brain changes in patients with Type 1 diabetes
... at patients with bipolar disorder or with classic neurodegenerative disorders, but this is the first study to use VBM to investigate brain changes in patients with diabetes," says co-investigator Perry Renshaw, M.D., Ph.D., who directs the Brain Imaging Center at McLean Hospital in Belmont, Mass. For the study, the ...Mutation in brain cells of descendants of Abraham Lincoln suggest he suffered from movement disorder
...ns Hopkins University School of Medicine. SCAs are neurodegenerative disorders that cause loss of coordination of limbs... and would increase public awareness of ataxia and neurodegenerative disease," Rothstein said. The finding also has wider implications because similar mutations might al...A new way of looking at molecular motors
...m certain kinds of blindness and kidney disease to neurodegenerative disorders and parasitic diseases such as malaria. ...ycystic kidney disease, brain development defects, neurodegenerative diseases, muscular dystrophy, skin pigmentation problems, and genetic hearing loss. Researchers led...A clue to core problem of neurodegenerative disease and cell death
...olded and damaged proteins are common to all human neurodegenerative diseases. Clumps of these aggregated proteins dest...l. If so, these findings have implications for all neurodegenerative diseases. For each disease, a single or a small number of mutant proteins have been identified as ca...Mad cow protein aids creation of brain cells
...nimals were incapable of contracting prion-related neurodegenerative disease when infected. Researchers knew then that PrP was necessary for mad-cow type diseases; any other kind of normal function remained unknown. Recently, researchers from the labs of Lindquist and Whitehead Member Harvey Lodish discovered that Pr...Study finds drug may cut down involuntary movements
...mark symptom of Huntington's disease, an inherited neurodegenerative disorder that worsens as brain cells known as medium spiny neurons are killed off by a mutant protein. The disease brings with it an array of other difficulties as well, including cognitive problems, changes in personality, and psychiatric problems ...New compound may protect against liver cancer
...ve role in a wide range of other illnesses such as neurodegenerative disease, asthma and emphysema. The study results are featured on the cover of the February 15, 2006 issue of the journal Cancer Research. "The results show that the potency of this compound is more than 100 times as great as that of other chemopreven...A better tool to study role of iron in Alzheimer's, Parkinson's
...de particles associated with Alzheimer's and other neurodegenerative diseases in the brain. The technique is likely to ... for studying the properties of "bad iron" tied to neurodegenerative diseases involve staining tissue sections to reveal the location of the iron, or extracting the part...Study implicates potassium channel mutations in neurodegeneration and mental retardation
...ene that regulates how potassium enters cells to a neurodegenerative disease and to another disorder that causes mental... the researchers looked for the gene that caused a neurodegenerative movement disorder called spinocerebellar ataxia in a Filipino family. This disorder typically appea...20 of world's top women scientists honored in Paris for groundbreaking research in life sciences
...er genetic investigations of Alzheimer's and other neurodegenerative disorders". Molecular biology and genetics, University of Antwerp, Research Director at the Institute Born-Bunge, Scientific Director of the Department of Molecular Genetics, Interuniversity Institute for Biotechnology, Flanders. Van Broeckhoven is...MIT research holds promise for Huntington's treatment
... the disease. There is no cure for Huntington's, a neurodegenerative disorder that now afflicts 30,000 Americans, with ...n a cellular model of Parkinson's disease, another neurodegenerative disorder caused by misfolded proteins. In Parkinson's disease, the mutant proteins destroy dopamine-...New tools developed for studying neurodegenerative brain disorders
...ange in the axon's shape that is characteristic of neurodegenerative disorders such as Alzheimer's and Parkinson's dise...es cause the destructive mechanisms that we see in neurodegenerative diseases," said coauthor and Assistant Professor of Veterinary and Biomedical Sciences, Anne Milasin...Study describes how cells return to normal after responding to stress
...t of new therapies for cardiovascular diseases and neurodegenerative diseases such as Alzheimer's. The study, which a... chronic protein misfolding is critical, including neurodegenerative diseases such as Alzheimer's, Parkinson's, and Huntington's. "So we expect that CHIP would play an i...MRI study opens door to assessing, preventing dangerous brain iron levels
...mage and formation of plaques found in age-related neurodegenerative disorders such as Alzheimer disease. In addition, past population studies show men develop such diseases about five years earlier than women but brain iron levels increase with age in both genders. "If you can measure it and learn how to modify it, ...'Bad' enzymes may wear white hats after stroke
...est problems facing stroke patients is that it's a neurodegenerative disorder, but also a medical emergency," he explained. "With other neurological disorders, such as Alzheimer's disease, the disease process is much slower. This study suggests that with stroke, we may now be able to think beyond acute treatment times...Inflammation and drugs to control this activity studied in a variety of tumors sites
...o explore their effects against cardiovascular and neurodegenerative diseases such as Alzheimer's disease. He hopes to continue to look at COX-2 blockers at sub-therapeutic doses in chemoprevention. "We need to look at a broader spectrum of conditions related to the inflammatory cascade and modulating the cascade with...New mechanism found for neurodegenerative effects of amphetamines in mice
...esearchers have discovered a new mechanism for the neurodegenerative effects of amphetamines. These drugs are converted...ree radicals, highly reactive molecules that cause neurodegenerative brain damage and whose effects manifest and linger long after the amphetamine has left the body. "T......tions in the future for understanding and treating neurodegenerative diseases. Using the brittlestar as a model is particularly useful as it is more closely related to vertebrates than previous models with extensive regeneration capabilities such as Hydra....