Double honors for diabetes researchers
...g methods for predicting foot ulceration caused by neuropathy and discovering that diabetes patients from South Asian descent were three times less prone to nerve damage than whites. More recently I have been investigating the reasons why Asian people with diabetes living in the UK have less peripheral nerve ...ACS News Service Weekly PressPac -- May 16, 2007
...ted States and Europe plus millions more who have neuropathy as a complication of diabetes. ARTICLE #4 FOR IMMEDIATE RELEASE "Current and Emerging Targets to Treat Neuropathic Pain" DOWNLOAD PDF http://pubs.acs.org/cgi-bin/sample.cgi/jmcmar/asap/pdf/jm061015w.pdf DOWNLOAD HTML http://pubs.acs.org/cgi-bi...Burroughs Wellcome Fund awards $14M to support physician-scientists
...h.D. Washington University Mechanism of peripheral neuropathy from Mitofusin 2 mutations James Elliott Bradner, M.D. Harvard University Design and characterization of highly potent inhibitors of HDAC6 Clark C. Chen, M.D., Ph.D. Harvard Medical School The molecular basis and therapeutic implications of g...News tips from the Journal of Neuroscience
...gene, pejvakin produce a nonprogressive auditory neuropathy as a result of defects in auditory nerve cells. In contrast, the mutation identified in this screen introduced a stop codon in pejvakin . This mutation resulted in progressive hearing loss caused by outer hair cell malfunction, suggesting distinct f...LSU professor uses tai chi to fight degenerative nerve disease
BATON ROUGE Peripheral neuropathy is a degenerative nerve disease with no cure and f...nto the benefits of tai chi for elderly peripheral neuropathy patients. So far, those practicing tai chi show far greater levels of improvement that those pursuin...Columbia University receives $16.9 million NIEHS award to study arsenic in ground water
...-carcinogenic effects such as diabetes, peripheral neuropathy and cardiovascular diseases, public health intervention strategies to reduce arsenic exposure are critical." The latest Superfund grant also includes a component studying the effects of environmental arsenic on children's health. While exposure to...Calorie restriction may prevent Alzheimer's through promotion of longevity program in the brain
...nnection between nutrition and Alzheimer's Disease neuropathy by defining mechanistic pathways in the brain and scrutinizing biochemical functions. We hope these findings further unlock the mystery of Alzheimer's and bring hope to the millions of Americans suffering from this disease." Alzheimer's Disease is a...Trial success for diabetic nerve therapy
...ients with long-term diabetes develop some form of neuropathy that can cause numbness and sometimes pain and wea...s, sex organs, eyes and digestive tract. "Diabetic neuropathy is a major problem in insulin-dependent diabetes, particularly in patients who have had the disease ...First clinical results reported for Sangamo's ZFP therapeutic
...d half of 2006." "Existing treatments for diabetic neuropathy are limited to the use of anti-depressants, analge...EO. "Diabetes is a chronic disease and peripheral neuropathy is a significant complication for the majority of long-term diabetics. We believe that SB-509 may p...News tips from the Journal of Neuroscience
...e mutation underlying an adult-onset demyelinating neuropathy (CharcotMarieTooth, Type 1B [CMT1B]), whereas the S63C mutation causes an early-onset demyelinating neuropathy Djrine-Sottas syndrome). Both mutant alleles caused a demyelinating neuropathydespite the coexistenc...JCI table of contents, February 1, 2006
...DNF rescues hyperglycemia-induced diabetic enteric neuropathy through activation of the PI3K/Akt pathwayAUTHOR CONTACT: Shanthi Srinivasan Emory University, Atlanta, Georgia, USA Phone: (404) 727-5298; Fax: (404) 712-2980; E-mail: ssrini2@emory.edu View the PDF of this article at: https://www.the-jci.org/ar...Discovery of new gene for rare nerve disease may help doctors understand more common illnesses
...ne in a family with CMT can help us understand how neuropathy develops in its most common form, for instance, in this country, that seen in people with diabetes." CMT is the most common inherited neurological disorder, affecting one in 2,500 people and involving the peripheral nerves, which are the structures t...Recycled or revamped therapeutics find novel anti-cancer applications
...nantly in transient skin rash, fatigue, peripheral neuropathy and constipation. One patient, however, developed a deep vein thrombosis and pulmonary embolism. The Efficacy of Novel Benzoylphenylureas Analogs in vitro and in a Novel Pancreas Cancer Direct Xenograft Model, and its Relationship with Microtubule-...Malfunctioning bone marrow cells sabotage nerve cells in diabetes
...appear to cause a dangerous nerve condition called neuropathy that disables many people with diabetes, said a re...ility. Discovering an underlying cause of diabetic neuropathy may enable us to design treatment strategies to prevent this complication in the future," concluded ...Diabetic nerve therapy shows 'striking' results
...iabetic neuropathies or nerve disorders. "Diabetic neuropathy is a major problem in insulin-dependent diabetes, ...ients with long-term diabetes develop some form of neuropathy that can cause numbness and sometimes pain and weakness in the hands, arms, feet and legs. Currently...Scientists use gene transfer technology and common virus to block neuropathic pain
...kin to small amounts of moderate heat. People with neuropathy perceive the filament's touch or heat as a painful sensation. Rats with neuropathy will lift their paw if the filament or heat produces pain. Rats without neuropathic pain don't even ...FDA approves ABRAXANE(TM) for metastatic breast cancer
...ons, severe myelosuppression, prolonged peripheral neuropathy and severe edema," said Edith Perez, M.D., Profess... with Taxol are not needed with ABRAXANE. Sensory neuropathy (all grades) occurred in 71% of patients treated with ABRAXANE and 56% treated with Taxol. Grade 3 ...Warning from new SLU research: Usual test for vitamin deficiency can mislead doctors
...deficiency is associated with dementia, peripheral neuropathy and spinal cord disease," says Florian Thomas, M.D., Ph.D., associate professor of neurology at Saint Louis University School of Medicine and a researcher on the project. "While it occurs at any age, B12 deficiency is more common in the elde...Gene therapy approach reverses diabetic neuropathy in animal model, Pitt study finds
... might some day help people with diabetes, in whom neuropathy is a common complication that causes irreversible ...py had complete reversal of established peripheral neuropathy and restoration of lost nerve endings to their feet, reported James R. Goss, Ph.D., research assista...