Scripps research scientists: Compounds show significant promise against potential bioweapon toxins
...ecules are the first to show efficacy against this neurotoxin in animal models. Equally important, both have sur...tances known to scientists. One subtype, botulinum neurotoxin A, is a 100 billion times more potent than cyanide and relatively easy to produce, making it a poten...Hotspots of mercury contamination identified in eastern North America
...e health. The team focused on levels of the potent neurotoxin in yellow perch and common loons, but it also took into account contamination in other fish, birds, and mammals. In addition to these hotspots in New England, New York, and Nova Scotia, the researchers found nine "areas of concern" in these regions a...Seeing a neurotoxin's deadly grip
...discovered new information about how the botulinum neurotoxin shuts down neurons with deadly efficiency. By prov...s to engineer specialized versions of the powerful neurotoxin that is used to treat a wide array of medical problems. The two groups were led by HHMI investigator...Botulism study could lead to new vaccines and treatments to counter bioterrorist attacks
...over in Germany have figured out how this powerful neurotoxin binds to and disables individual nerve cells. Rese...hree-dimensional, atomic-scale images of botulinum neurotoxin binding to its specific protein receptor on the surface of a neuron. The scientists discovered that ...Study helps explain why botulinum toxin is so deadly
...o show in atomic detail the structure of botulinum neurotoxin touching the receptor on the surface of the neuron," Chapman says. "The toxin has to bind to the neuron it wants to poison. This is a snapshot of the first stage of that poisoning." The report on the work, in the journal Nature this week, identified ...ACS News Service Weekly PressPac -- August 9, 2006
...r the heart - Strategies emerge for dealing with a neurotoxin and probable human carcinogen in food - Special Ev...ug. 14, 2006 Strategies emerge for dealing with a neurotoxin and probable human carcinogen in food Chemical & Engineering News Scientists now can identify str...Researchers discover botulism toxin's insidious route into nerve cells
Botulinum neurotoxin A can be either the greatest wrinkle remover or on...has identified the cellular receptor for botulinum neurotoxin A. The group's work was published in the March 16, 2006, edition of ScienceXpress, which provides el...Scientists reveal how deadly toxin hijacks cells
...- Scientists have pinpointed exactly how botulinum neurotoxin A - a potential agent of biological warfare and one of the most lethal toxins known to man - is able to sneak into cells. The finding is crucial for the development of new treatments against botulism, a paralytic illness caused by the toxin more com...Newly discovered small molecules
...dy, these activators bind to specific sites on the neurotoxin protein, increasing protease activity and enhancin...at conducted the study, said, "Since the botulinum neurotoxin is the most poisonous toxin known, finding a compound to activate it might seem somewhat counterprod...Botox could help target resistant tumors for treatment
...ussels, Belgium, found that by injecting Botulinum neurotoxin type A into two types of mouse tumors, the tumors' cellular vasculature opened, allowing for more effective destruction of previously resistant cancer cells. The study is the first to test the idea of using Botox against cancer and explores the possi...Researcher finds new use for botox
...ouncil funded research. "Botox is the most potent neurotoxin currently known," Dr Meunier said. "It derives from the bacterium Clostridium botulinum, which causes botulism (food poisoning). "However, botox is increasingly used in human therapy to treat such conditions as strabismus (cross-eyes), voice, head ...Tetanus toxin found to have therapeutic properties
...rs such as Parkinson's disease. Tetanus toxin is a neurotoxin belonging to the same family as botulinum neurotoxins, which cause botulism. These have been successfully used as a therapy to treat disorders caused by abnormal muscular contractions such as strabismus, cerebral palsy, anal contractions and torticol...National medical, nursing and public health groups file suit
...scientific research shows that mercury is a potent neurotoxin that can harm developing fetuses in the womb, young children, and at higher doses, adults. Once consumed through fish and other sources, mercury travels through a mother's bloodstream, crosses the placenta and can harm healthy brain development in ...Researchers show how botulism toxin ensnares its target
... was known previously is that other regions of the neurotoxin protein, which they called "exosites," might be in...denbach created crystals of a particular botulinum neurotoxin bound to its target SNARE. The researchers determined the structure of the bound proteins using x-ra...Scientists solve the mystery of how Botox attacks nerves and eliminates wrinkles
...ctually receiving minute injections of a bacterial neurotoxin called botulinum, one of the most poisonous substa...ever machinery There are seven forms of botulinum neurotoxin produced by seven different strains of the Clostridium botulinum bacterium, explained Brunger, a How...Pesticides may promote Parkinson's disease and exercise may offer protection
...e University of Pittsburgh. "The injections of the neurotoxin used to mimic Parkinson's were made in a way that ...chers found that after mice were injected with the neurotoxin 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP), which stimulates Parkinson's symptoms by killin...