Study identifies molecular complex vital to creation of miRNAs
...lved in miRNA processing, but the role of DGCR8 is newly seen here. The Wistar scientists showed that both DGCR8 and Drosha were necessary for the processing of primary miRNA into a precursor miRNA neither alone was sufficient to do the job. In another set of experiments, DGCR8 was intentionally inactivat...Random gene activation helps ulcer bug escape immune system
...ly to cells of the stomach lining to feed, but the newly identified interaction ensures that a small reservoir of bacteria are always more loosely connected. This reservoir is much more likely to survive if the host mounts a strong immune response. "Basically, if you're holding onto someone's T-shirt and ...Census of Marine Life - Discoveries and Highlights 2004: Scientists add 4m+ records, 13,000 species
...es to assess and monitor marine life. For example, newly field tested equipment and techniques reveal hundr...sophisticated filtration and gene sequencing. And newly developed protocols for the inventory of near-shore coastal biodiversity enable comparative worldwid...Genetic discovery paves way to decode sense of smell in mammals
...d microbiology at Duke. By taking advantage of the newly discovered components of the olfactory machinery, ...made it possible for the researchers to induce the newly created cells to express odorant receptors at their surfaces. The team then tested the receptors' re...Columbia researchers identify drug as therapeutic candidate for spinal muscular atrophy
New York, Nov. 29 Using a newly developed technology, a team of Columbia University researchers has uncovered that indoprofen, a nonsteroidal anti-inflammatory drug, may increase the production of a protein lacking in patients with spinal muscular atrophy (SMA), a fatal pediatric g...Global assessments of biodiversity argue for expansion of protected areas in key regions
... coauthors, assesses high-quality global databases newly available for conservation planning. It notes that coverage by protected areas varies geographically, but is less than 2 percent for some bioregions, such as the tropical dry forests of Mexico, the mediterranean habitats of Chile, and the temperate g...JCI table of contents, December 1 2004
....org/press/15707.pdf GLUT4 is at the center of a newly found mechanism of triglyceride production and utilization in type 2 diabetes TITLE: GLUT4 glucose transporter deficiency increases hepatic lipid production and peripheral lipid utilization AUTHOR CONTACT: Barbara B. Kahn Beth Israel Deaconess Medic...Wolfgang Heckl awarded Descartes Prize for Science Communication
...dent of the Czech Republic, and Janez Potonik, the newly appointed EU Commissioner for Science and Research. The highly respected Descartes Prize for Excellence in collaborative scientific research, worth 500,000, was awarded for the fifth time. This year it was awarded to two teams in the fields of life ...NIDCR launches unique initiative on oral biofilm
... or cause disease, such as periodontitis. In the newly launched NIDCR-supported study, the scientists will employ metagenomics, an investigative strategy first proposed nearly 20 years ago but which has become increasingly popular over the past few years. Metagenomic techniques re-build genomes from sm...What have scientists learned since Mount St. Helens erupted?
...dispersal corridors between source populations and newly created habitat patches. These oases habitats were of tremendous importance to the overall biodiversity of the larger landscape, they contributed much of the biodiversity. "St. Helens has had a very active eruptive past, and if history provides any ...Canola study solves seed oil mystery
...red to be much more efficient than glycolysis. The newly uncovered Rubisco bypass pathway produced 20 percent more of the carbon-chain building blocks to make oil while losing 40 percent less carbon dioxide than is lost during glycolysis. The results cast new light on the seemingly well-understo...Dream home: Malaria parasite renovates to suit its tastes
...od cells in which it dwells. Once ensconced in its newly refurbished home, the parasite evades detection by the host's immune system. Alan F. Cowman, a Howard Hughes Medical Institute (HHMI) international research scholar at the Walter and Eliza Hall Institute of Medical Research in Melbourne, Australia, a...Genetic defect confers risk of major depression, resistance to SSRI drug therapy
DURHAM, N.C. A newly discovered genetic defect might represent an important risk factor for major depression, a condition which effects 20 million people in the U.S., according to Duke University Medical Center researchers. The mutation in the gene -- whose protein produ...Discovery about Vitamin C explains its metabolic value
...arch, the OSU team plans to study the role of this newly understood reaction between vitamin C and toxic lipids in atherosclerosis. In clinical studies they plan to examine the blood chemistry of patients who have been diagnosed with coronary artery disease, compared to a healthy control group. "In the ear......ory at PNNL. A key change in the properties of the newly formed nitrate particles is that they begin to absorb water and retain the moisture. These wet particles can scatter and absorb sunlight -- presenting climate modelers, who need to know where the energy is going, a new wild card to deal with. Compani...JCI table of contents, December 15 2004
...er in order to prevent the body from attacking the newly transferred T cells. The "T body" approach decreased tumor growth, prolonged survival, and even cured the treated mice. The authors suggest that patient preconditioning prior to the transfer of tumor-specific T cells offers great promise for immunot......t the University of Mainz in 1995. He has held the newly established chair for theoretical chemistry there since 2001. Prof. Dr. Gnther G. Hasinger (50), Astrophysics, Max Planck Institute for Extraterrestrial Physics, Garching (1.55 million euros) Gnther Hasinger is one of the world's leading researcher...New compound could enhance cancer treatments
...ear, second only to heart disease. Here is how the newly discovered compound works: Most anti-cancer drugs work by causing cell damage, such as DNA damage, which ultimately kills the cancer cells. However, cancer cells are also prone to repair themselves and survive the damage done by drugs, which renders ...Combined stem cell-gene therapy approach seen as potential treatment for cystic fibrosis
...n, or PCR, confirmed the gene was expressed in the newly differentiated airway epithelial cells, reported Guoshun Wang, M.D., D.D.M, of Louisiana State University (LSU), where Dr. Kolls previously had worked, and Bruce A. Bunnell, Ph.D, of Tulane University, the study's first authors. Moreover, the gene th...Body's biological clock found to affect cardiac rhythm patterns in healthy adults
(Boston) -- In a newly reported, first-ever finding, physicists from Boston University and physiologists from Boston's Brigham and Women's Hospital (BWH) have found that the body's biological clock affects the patterns of heart-rate control in healthy individuals independe...