Tag: "nitric" at biology news

National Science Foundation awards $2 million grant to UC Riverside

...emissions. Some of this is converted to nitrate or nitric acid, the form of nitrogen (known as N) that is used by plants as fertilizer. "California has been subject to weed invasions since the arrival of the first European settlers, but the southern California coastal sage scrub and deserts have been exper...

Running not swimming or biking is best kind of loading exercise for childrens bone growth

..., and second messengers such as prostaglandins and nitric oxide. Specific targets of mechanical loading include the L-type calcium channel (alpha 1C isoform), a gadolinium-sensitive stretch-activated channel, P2Y2 and P2X7 purinergic receptors, EP2 and EP4 prostanoid receptors, and the parathyroid hormone r...

Botulism bug says no to nitric oxide, provides key to molecule's role in human cell signaling

...on transformed one of nature's simplest molecules, nitric oxide (NO), from a toxin to anaerobic bacteria th...how botulism-causing Clostridium botulinum detects nitric oxide (NO) sheds light on how NO connects with its receptor protein in humans to govern crucial proc...

Stony Brook University medical researcher developing new medication to prevent colon cancer

...e disease. The study of the new medication--called nitric oxide-donating aspirin, or nitroaspirin--is supported by a $3.2 million grant from the National Cancer Institute. Basil Rigas, M.D., Professor of Medicine and Chief of the Division of Cancer Prevention at Stony Brook's School of Medicine, will repor...

Early life stress harms mental function and immune system in later years

...mmune challenges may be due in part to deficits in nitric oxide, a signaling system in the brain known to co...on, and the researchers measured the expression of nitric oxide synthase, a gene critical for production of nitric oxide in the nervous system. About six anim...

Nitric oxide is essential for animal development

...sophila genetics, researchers have discovered that nitric oxide (NO), a versatile signalling molecule involved in a diversity of clinically important cellular functions, is essential for an organism's development. NO has been the most intensely studied signalling molecule for more than a decade. Produced b...

New Italian research links migraine and endometriosis

...o been shown that upregulation or disregulation of nitric oxide synthesis has a role in both migraine and endometriosis. But the association between the two conditions requires further research."...

Red wine mist? Resveratrol shows potential effects against COPD, asthma, arthritis

...ression in HAEC. The inhibition of iNOS (inducible nitric oxide synthase) expression and activity in primary HAEC is significant, because steroids are ineffective in this system," the paper states. IL-8 (interleukin-8) and GM-CSF (granulocyte-macrophage colony-stimulating factor) are important in the inflam...

UO study is first to link histamine receptors to heat stress

...forearms and used microdialysis to target doses of nitric oxide or two types of antihistamines. Laser-Doppler flowmetry (LDF) was used to monitor changes in skin blood flow during heat stress. "I personally don't like needles but it's a very powerful technique to study skin blood flow," says Wong, who...

The secret life of acid dust

... particles blow into the air and encounter gaseous nitric acid in polluted air from factories to form an ent...in the mineral, the more reactive they are in with nitric acid. And once the particle is changed, it stays that way. "When dust storms kick up these particles...

Discovery promises simpler therapy for sickle cell disease

...ells to relax blood vessels through the release of nitric oxide is a major factor behind the disease's prima...in, clots and stroke. Thus, therapies that restore nitric oxide to blood cells might serve as a useful method for treating the disease, said HHMI researcher J...

VCU research shows erectile dysfunction drug reduces death of heart cells in heart attack model

...vant concentrations produced therapeutic levels of nitric oxide (NO) in the heart cells of mice by increasin...repared from genetically engineered mice that lack nitric oxide synthesizing enzymes. The model was particularly useful in studying the protective effect of s...

Duke researchers uncover genetic link to kidney damage after heart surgery

... involved in vascular responsiveness endothelial nitric oxide synthase 849T and angiotensin converting enzyme deletion allele had a 162.5 percent increase in creatinine in the blood. This translates into a 60 percent reduction in the kidney's filtering ability, a rate more than twice as high as the study...

Researchers report new pro-inflammatory role for anti-inflammatory enzyme

...tory response to bacterial invasion is to increase nitric oxide levels with an enzyme called inducible nitric oxide synthase. In a study published in the Journal of Biological Chemistry, scientists report that ...

Disease diagnosis, biodefense among UH chemical research projects

... heme proteins found in certain insects that store nitric oxide (NO). Having importance in many areas of human health, NO is useful in lowering blood pressure, treating cancer and increasing oxygen absorption in lung tissue. Czernuszewicz's research is focused on the roles of salivary nitrophorins in stor...

Polymers with copper show promise for implanted sensors

...y with intravascular sensors that were coated with nitric oxide-releasing polymers has promising preliminary... strategy: creating polymer coatings that generate nitric oxide from components already in the blood. U-M chemistry professor Mark Meyerhoff will discuss the ...

UC Davis researchers discover new link between C-reactive protein, and heart disease and stroke

...e protein causes endothelial cells to produce less nitric oxide and to increase the number of cell adhesion molecules. This, in turn, allows damaging leukocytes to enter the vessels. Devaraj and Jialal also showed that C-reactive protein induces endothelial cells to produce plasminogen activator inhibitor, ...

Thumbnail sampler of 10 diverse physiology papers from IUPS 2005

..., they determined kidney function before and after nitric oxide blockade. The found that renal function was ...d that the damaged kidney didn't appear to produce nitric oxide; if so, this may account for the further reduction in kidney function in the hypertensive grou...

Nitrite says NO to ischemia/reperfusion injury

... simple inorganic anion that is the end product of nitric oxide (NO) oxidation, and previously thought to have only limited biological activity. In a study appearing online on April 14 in advance of the print publication of the May issue of the Journal of Clinical Investigation , David Lefer and colleagues...

JCI table of contents May 1, 2005

... simple inorganic anion that is the end product of nitric oxide (NO) oxidation, and previously thought to ha...nsequent heart failure. TITLE: Oxidant stress from nitric oxide synthase-3 uncoupling stimulates cardiac pathologic remodeling from chronic pressure-load AUTH...

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(Date:6/18/2013)... Arlington environmental engineer has been awarded a $394,300 ... ensure water quality and flow in the new ... Andrew Kruzic, UT Arlington associate professor of civil ... to add monochloramine to the water in an ... pump stations and pipelines. Adding monochloramine is widely ...
(Date:6/18/2013)... The National Institutes of Health has awarded $12.7 ... a selection of pharmaceutical industry compounds to explore ... including Alzheimer,s disease, Duchenne muscular dystrophy and schizophrenia. ... Uses for Existing Molecules, is led by the ... funded by the NIH Common Fund. , The ...
(Date:6/18/2013)... 10% of breast and ovarian cancers are familial in ... attributable to inherited mutations from the parents in genes ... mutations, PARP inhibitors, which are currently in clinical trials, ... option for personalised cancer treatment, an alternative to standard ... of these patients generate resistance to the drug and, ...
Breaking Biology News(10 mins):UT Arlington research to benefit quality, flow in 150-mile Integrated Pipeline 2NIH to fund collaborations with industry to identify new uses for existing compounds 2NIH to fund collaborations with industry to identify new uses for existing compounds 3NIH to fund collaborations with industry to identify new uses for existing compounds 4An article in 'Cell' reveals a new resistance mechanism to chemotherapy in breast and ovarian cancer 2
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