American Chemical Society's Weekly PressPac -- Aug. 8, 2007
...d metabolize and change trinitrotoluene (TNT) into nontoxic compounds. But those natural bacteria exist at levels too low to detoxify TNT. In the new study, researchers inserted a gene for a TNT-transforming bacterial enzyme into a tobacco plant. Then they tested the plants effect on TNT-contaminated soil...Under magnetic force, nanoparticles may deliver gene therapy
...re biodegradable, so they break down into simpler, nontoxic chemicals that can be carried away in the blood. Previous researchers had shown that magnetically driven nanoparticles could deliver DNA in cell cultures, but ours is the first delivery system that is biodegradable, and therefore, safer to use in peo...Plastic that degrades in seawater could be boon for cruise industry and others
...seawater, the plastics degrade via hydrolysis into nontoxic products, according to the scientists. Depending on the composition of the plastics, these compounds may include water, carbon dioxide, lactic acid, glycolic acid, succinic acid, caproic acid and L-lysine, all of which can be found in nature, they ad...Ingredient in Big Macs and sodas can stabilize
...ered by the difficulty of making them in a stable, nontoxic form that can be injected into a patient. New rese...a new type of gold nanoparticle that is stable and nontoxic and can be administered orally or injected. Because gold nanoparticles have a high surface reactiv...A form of the alcohol dehydrogenase gene may protect Afro-Trinidadians from developing alcoholism
... breaks down acetaldehyde to acetate, a relatively nontoxic compound." Ehlers said that most people do not realize that people of different racial origins metabolize alcohol differently and that this influences their risk for alcoholism. "Approximately 40 percent of Asians have a mutation in ALDH that may ...Invitrogen features new scientific online resources at ASCB Meeting
...logy. Conveniently pre-packaged in the biosafe and nontoxic BacMam insect virus delivery format, Premo cameleon is designed for live-cell application to a broad range of mammalian cells, including neuronal, primary and stem cells. Other Invitrogen ASCB activities include: Workshop: Gene expression profilin...Non-steroidal anti-inflammatory drug increases liver damage in mice carrying mutant human gene
...ethacin (Indocin), administered at doses typically nontoxic to mice, significantly increased liver damage in the experimental mice. The mice carried a mutated form of the human alpha-1-AT gene (called the alpha-1-ATZ gene), the most common form of the gene associated with the development of liver disease in...U of MN Center for Drug Design awarded $2.5 million grant
...eries of antidotes that can convert cyanide into a nontoxic substance through the use of a cellular enzyme. These antidotes are quicker than current treatment and can be delivered either orally or intravenously. This study aims to expand the efficiency, bioavailability, and physical properties of these anti...MIT material stops bleeding in seconds
...und and halts bleeding. Once the injury heals, the nontoxic gel is broken down into molecules that cells can use as building blocks for tissue repair. "We have found a way to stop bleeding, in less than 15 seconds, that could revolutionize bleeding control," said Rutledge Ellis-Behnke, research scientist in ...ACS News Service Weekly PressPac -- August 9, 2006
...d poultry - A new generation of removable, colored nontoxic coatings - First test results on a new nano elec...TE RELEASE A new generation of removable, colored nontoxic coatings BiomacromoleculesErasable graffiti? Imagine writing "Happy Birthday Mom!" in flamingo p...Researchers attack tumor cells by exploiting dependency on sugar metabolism
...ition of LDH-A activity may represent a relatively nontoxic approach to interfere with tumor growth," explains Dr. Fantin....ACS weekly press package — May 1st, 2006
...ce of cells. Tests showed that the coated CNTwere nontoxic to cells, while uncoated CNTs killed cells. "Thisapproach for interfacing CNTs with cells should accelerate their use inbiological systems," the researchers said. Since glycans also are involvedin a cell's ability to recognize and bind, the approach ...Modifications render carbon nanotubes nontoxic
...s that nanotubes, like buckyballs, can be rendered nontoxic with minor chemical modifications. The findings come from the first toxicological studies of water-soluble carbon nanotubes. The study, which is available online, will be published in an upcoming issue of the journal Toxicology Letters. The research ...Research team develops cancer-curing T-lymphocyte-based therapy to eradicate malignant tumours
...s work leading to the development of an effective, nontoxic and non-invasive therapy against certain types of cancer for broad clinical use isexciting for every basic research students, scientist and doctors working on this project." "Malignant melanoma is a devastating disease, affecting 4,300 Canadians this...University of Delaware researchers develop cancer 'nanobomb'
...ecause they are powerful, selective, non-invasive, nontoxic and can incorporate current technology, including microsurgery. An advantage over other carbon nanotube treatments being considered by scientists is that with nanobombs, the carbon nanotubes are destroyed along with the cancer cells. Once the nanob...'Cookbook recipes' would cure disease with nontoxic DNA delivery systems
...molecules have created a "cookbook" for a class of nontoxic DNA delivery systems that will assist doctors and clinicians in the safe and effective delivery of genetic medicine. As reported in the Aug. 9 issue of the Proceedings of the National Academy of Sciences, researchers have now performed a careful, com...Critical step traced in anthrax infection
... of Science . An anthrax bacterium secretes three nontoxic proteins that assemble into a toxic complex on the surface of the host cell to set off a chain of events leading to cell toxicity and death. Protective antigen (PA) is one of these proteins, and after binding to the cell, seven copies of it assemble ...Tips from the Journals of the American Society for Microbiology
... a strong inhibition of coronavirus replication at nontoxic drug concentrations. "These findings demonstrate that the old drug cinanserin is an inhibitor of SARS-CoV replication, acting most likely via inhibition of the 3CL proteinase," say the researchers. (L. Chen, C. Gui, X. Luo, Q. Yang, S. Gunther, E. Sc...Brain-mapping technique aids understanding of sleep, wakefulness
... in a certain population of neurons. The tracer, a nontoxic fragment of the tetanus toxin, transfers itself from one neuron in retrograde fashion to neurons "upstream" -- those from which the tracer-producing neuron receives signals. Researchers then track the tracer to map the upstream neurons. Dr. Yanagisa...Researchers uncover mutated genes involved in lung cancer; one affects nonsmokers
...kely will have a dramatic response to a relatively nontoxic once-daily oral therapy," Dr. Minna said. "The research has found these tumors can vary by several thousandfold on how sensitive they are to a drug," said Dr. Minna. "We also have been able to identify in advance a pattern of gene expression that te...