Chronically sleep deprived? You can't make up for lost sleep
..., or in their sleep homeostat, in situations where normal sleep time is prohibited or where sleep could be detrimental for survival. An extreme but realistic example of this, says Turek, would be how animals respond to catastrophic environmental conditions, such as Hurricane Katrina. No matter how sleep dep...Antibody linked to MS significantly higher in spinal fluid of blacks
...vels of IgG. Since everyone makes IgG as a part of normal immune function, scientists have to assess cerebrospinal IgG levels using an index that also factors in the amount of IgG in the patient's blood and the integrity of the blood-brain barrier, which limits access to the brain. "High IgG levels in a he...JCI Table of Contents -- July 2, 2007
...act, cell membrane rupture occurs frequently under normal conditions but to prevent cell death cells have de...and that stress exercise was sufficient to disturb normal cardiac function in dysferlin-deficient mice. Cardiac damage was even more severe in mice bred by cr...Endometriosis increases the risk of certain cancers
... by more than a third (37%) above the risk for the normal population of women without endometriosis. There were similar increases in risk for endocrine tumours (38%), kidney cancer (36%) and thyroid cancer (33%). Slightly lower increases were found for brain tumours (27%) and malignant melanoma (23%), and t...Tick-related disease thrives on cholesterol, study suggests
...e group lacked a protein important for maintaining normal blood cholesterol levels, while mice in the other ...rol, while the rest of the animals ate a diet with normal cholesterol levels. At the end of the month, some of the mice from each feeding group were infected ...M. D. Anderson team identifies new oncogene for brain cancer
...ypes. The gene is expressed only at low levels in normal cells, which would potentially reduce side effects caused by a treatment that targeted the gene or its protein product. Fuller and Zhang first associated overexpression of the gene with brain cancer in 1999. Other researchers have since found it t...Personalized approach to ovarian stimulation achieves high ART pregnancy rates
...when women were evaluated for fertility treatment: normal (or basal) levels of follicle stimulating hormone (FSH), body mass index, age and the number of small growing (antral) follicles in the ovary detected during screening. This FSH dose algorithm is simple and easy to use and utilises readily availab...Time-lapse recordings reveal why IVF embryos are more likely to develop into twins
...yst collapse in the laboratory was thought to be a normal feature of blastocyst development. However, our findings that collapse was associated with degeneration of blastocysts as well as the formation of the second ICM suggest that these episodes in which blastocoele volume cannot be maintained may be an a...Marine worm opens new window on early cell development
...ring from a variety of cancers, a breakdown in the normal regulation of beta-catenin signaling is thought to be responsible for the growth of related tumors. Coupled with similar findings involving beta-catenin in the nematode Caenorhabditis elegans, a roundworm found in soil, the new UO report suggests an ...Cell receptor may lead to new 'biomarker' for pancreatic cancer
...ons -- for example cell growth and migration. A normal pancreas has very low levels of RON, but our study showed that as tumors progress, so does the level of RON expression in the pancreas cells -- and those overexpressed levels were maintained in metastases, the areas that the tumors spread to, explain...SNM initiatives supported by inclusions in NAS Report on competitiveness of US chemistry research
...t for more precise localization of radiotracers in normal and aberrant cell physiologies; national impediments to the efficient entry of promising new radiopharmaceutical compounds into clinical feasibility studies and strategies to overcome them and impacts of shortages of isotopes and highly trained radio...Loss of cell's 'antenna' linked to cancer's development
...And increasingly, biologists are finding that most normal vertebrate cells have cilia, small hair-like struc... detection and in helping an embryo develop into a normal baby. Defects in cilia can produce a range of disorders, including kidney cysts, infertility, respi...Autism theory put to the test with new technology
...ve a problem with their mirror neuron system. In normal individuals if you see someone throwing a ball, your mind will mirror those actions to make it seem as if you are throwing it yourself, Welsh explains. The theory is that a person with autism may not be able to mirror the actions of other individuals...New genetic test developed at Emory advances detection and diagnosis of muscular dystrophy
...vent mutations in the dystrophin gene and increase normal gene expression. According to Dr. Hegde, about 13 percent of mutations in the dystrophin gene are nonsense mutations--point mutations in a sequence of DNA that can result in mistakes in gene expression and nonfunctional proteins. New data published...Support for chromosomal theory of cancer found in cancers' development of drug resistance
... from a drug, he said, is that it is less toxic to normal cells than cancer cells, and that as a result a ca...son" that happens to kill more leukemia cells than normal cells. Development of drug resistance in cancer is one of the strongest arguments for the aneuploi...Researchers find gene that spurs development of the epididymis
...llows it to swim. So without this structure, under normal circumstances a male cannot be fertile. The rese...atter half of the life of an embryo. But all the normal indicators of adequate testosterone levels (its production and other physiological characteristics) ...Story ideas from Molecular & Cellular Proteomics
...questions include how this protein is expressed in normal and cancer cells, how it helps cancer cells escape...gues discovered that clusterin is not expressed in normal cells, while in 25 percent of colorectal tumors, the cancer cells contained clusterin. They also sho...News tips from the Journal of Neuroscience
...fied DNA in single neurons in entorhinal cortex of normal and AD brains, using three techniques: slide-based...expression of cyclin B1, a mitotic marker. In both normal and AD brains, a small population of neurons contained more DNA than the normal diploid content; som...Weizmann scientists discover a new line of communication between nervous system cells
... nerves a discovery that may aid in restoring the normal function of the affected nerve fibers. Nerve cells (neurons) have long, thin extensions called axons that can reach up to a meter and or more in length. Often, these extensions are covered by myelin, which is formed by a group of specialized cells ...Penn researchers report that gene therapy awakens the brain despite blindness from birth
...ation had intact visual brain pathways with nearly normal structure. The Penn team also found that, while t... lights was comparable to that of individuals with normal sight. "It seems these patients have the necessary brain pathways ready to go if their eyes start...