Super fruit fly may lead to healthier humans
...y GPCRs figure prominently indisease as well as in normal development, Roberts said. It is the most targeted family of receptors by drug manufacturers, Robertssaid, estimating that a quarter of all pharmaceuticals focus on GPCRs. This approach should be generally applicable. And generally powerful, gi...QUT microgravity tower attracts global scientific community
... insights into phenomena not able to be studied in normal gravity since the effects of buoyancy, sedimentati...ts produces stronger structures than are formed in normal gravity....Talcum powder stunts growth of lung tumors
...as gone, Antony said. What weve done is caused the normal pleural mesothelial cells to continue to produce e... stays in the chest cavity, constantly causing the normal cells to produce this factor that inhibits the growth of the tumor. The antitumor effects of talc ...University of Pittsburgh scientists find new contributor to aggressive cancers
...medium after increasing or decreasing the level of normal integrin 7 in the cell lines. In this experiment, ...onies with up to 100 cells each. Cancer cells with normal levels of integrin 7 expression formed fewer and smaller colonies. When the investigators decreased ...New clues to stroke role in Alzheimer's
...ring stroke or head trauma also interfere with the normal disposal of an enzyme that helps generate plaque. This interference increases the level of the enzyme in brain cells, they found. The researchers, led by Giuseppina Tesco and Rudolph Tanzi of Massachusetts General Hospital, reported their findings ...Research team identifies new Alzheimer's gene
...archers hypothesize that GAB2 might function under normal conditions to compensate for the harmful effects of APOE4 and other genes in older people and that the GAB2 risk gene lacks this protective effect. The study, funded by Kronos Science Laboratory, an affiliate of Phoenix-based Kronos Optimal Health...UCLA researchers reprogram normal tissue cells into embryonic stem cells
...ell Biology and Medicine at UCLA were able to take normal tissue cells and reprogram them into cells with th...human cells. If we can successfully reprogram a normal human cell into a cell with almost identical properties to those in embryonic stem cells without SCN...Reprogrammed fibroblasts identical to embryonic stem cells
...ny substantial differences between these cells and normal embryonic stem cells. In all tests, both genetic and epigenetic, there were no molecular markers distinguishing these two groups, says Meissner. But definitive proof would only come through demonstrating that these cells could actually develop i...A twist of fate -- Reprogrammed fibroblasts resemble embryonic stem cells
...er exciting leap forward as scientists report that normal tissue cells can be reprogrammed to exhibit many of the properties that are characteristic of embryonic stem cells, including the ability to give rise to multiple cell types and contribute to the germline. These findings, published in the inaugural i...New algorithms classify outcomes of nonsmall cell lung cancer patients
...nalyzed protein patterns in NSCLC tumor tissue and normal lung tissue. The researchers identified a pattern that was associated with increased survival among NSCLC patients and may distinguish patients with poor prognosis from those with good prognosis. They also tested their model on independent validation...Older men may not live as long if they have low testosterone
...sterone" levels were set at the lower limit of the normal range for young adult men. Testosterone declines slowly with aging in men and levels vary widely, with many older men still having testosterone levels in the range of young men. Twenty-nine percent of Rancho Bernardo men had low testosterone. D...Finding protection from tumor growth in unexpected places
.... When injected with aggressive melanoma cells, normal mice developed large melanoma tumors whereas ACE 1...nce of an ACE-specific anti-tumor immune response, normal mice were depleted of their bone marrow and transplanted with ACE 10/10 bone marrow. When the transp...It's safe for obese moms-to-be to lose weight during pregnancy, new SLU research finds
... maintained their weight were more likely to be of normal size. Infants born to women who gained weight were more likely to be bigger 8 pounds, 8 ounces and heavier. More women who gained weight during pregnancy delivered their babies by Caesarian section than those who lost or kept their weight constan...Uncovering the molecular basis of obesity
...centration of feeding hormones in their brain than normal mice. Being conserved across species Bsx might be ...ck Bsx in their hypothalamus are a lot lazier than normal mice. They show less spontaneous activity and less food seeking behaviour, which is based on locomot...Other highlights from the June 6 JNCI
...ncer and leiomyosarcoma cell lines was restored to normal levels, tumors generated from these cells grew more slowly and produced fewer metastates. The ubiquitous expression of integrin 7 in human organs and widespread mutations of this gene in human cancers raise the possibility that integrin 7 may have ...American Chemical Society's Weekly PressPac -- May 30, 2007
...ivery vehicles, for replacing defective genes with normal copies. In SCD, a mutation in the gene that encode...esearchers showed that SB-Tn system could transfer normal beta globin genes into cells. The system, named for a fish gene reawakened by other researchers in...PET/CT use expands: Effectively diagnosing graft infections
...tive substances (such as FDG) that are taken up by normal organs and disease processes characterized by increased function and metabolism, such as cancer or infection. CT offers a detailed map of internal anatomy. "Combined PET/CT, therefore, enables both diagnosis of infection and determination of its prec...What causes Alzheimer's? Researchers tie beta-amyloids to brain dysfunction
...ssociated with brain dysfunctioneven in apparently normal elderly individualsproviding further evidence that...tioning within the body. "We found that apparently normal elderly subjects with positive PIB PET scans do have mildbut significantreduction in memory test sco...PET/CT should be 'first-step' test for patients with Crohn's disease
...onoscopy showed severe lesions and PET/CT showed a normal metabolic activity," said Hustinx. "Conversely, this means that when the PET/CT is negativeno matter how important the clinical symptoms arethe disease is not active," he added. "PET/CT has, therefore, the potential to deeply modify the exploration a......Cancer cells metabolize sugar at higher rates than normal cells, and the radiopharmaceutical is drawn in higher concentrations to cancerous areas. PET scans show where FDG is by measuring the high-energy photons emitted by the drug and produce three-dimensional images of those substances functioning within ...