Tag: "novel" at biology news

University of Leeds strengthens China links in membrane and neurobiology

...receptors, which potentially represent targets for novel antibacterial, antiparasite and antidiabetic drugs. Complementing such studies, another major theme of the initiative concerns the flow of membranes between different cellular compartments and its dysfunction in disease. The initiative is supporte...

New joint replacement material developed at MGH put to first clinical use

... hip replacement using a joint socket lined with a novel material invented at the MGH. An advance over first-generation highly crosslinked polyethylene, which was also developed at MGH and significantly reduced a serious complication of early hip implants, the new material may be applied in replacements f...

UB scientist discovers novel iron-copper alliance

...tions, and life cannot be sustained without it. In novel research, investigators at the University at Buffalos School of Public Health and Health Professions, have learned that iron is only one half of an all-important duo of trace minerals -- the other being copper -- that work in tandem to maintain prope...

Neurons for numerosity: Parietal neurons 'sum up' individual items in a group

... from the University of Illinois at Chicago report novel evidence for the existence of accumulator neurons, which respond to increasing numbers of items in a display with progressively increasing activity, in the parietal cortex of monkeys. The authors focused on the parietal cortex based on evidence th...

A novel molecular dictator 'with a conscience' discovered

...olecular assassin" drug technology, describes this novel mechanism he discovered as a molecular dictatorship with a conscience. "The dictator is a specific gene suppressor called YY1, which has the therapeutically appealing capacity to differentiate between certain cell types when it goes about its act...

Genomic analysis uncovers new targets for HIV vaccine

... others, Goldstein. This should ultimately lead to novel targets for vaccines, the primary goal of CHAVI. Two of the polymorphisms found were in genes controlling the human leukocyte antigen (HLA) system, which plays a major role in the immune system by identifying foreign invaders and tagging them for d...

A brain chemical that battles despair

...ess "Our present results provide a fundamentally novel and testable model for the mechanisms of resilience," concluded the researchers. "Our future studies will test the hypothesis that antidepressant treatments may enhance resilience by stimulating these same adaptive processes which occur spontaneously...

Study explains how pathogens evolve to escape detection

...and attack organisms, the organisms in turn create novel defenses, each in a continuous battle to outdo the other, said Rosebrock....

Vaccine trials inject hope into koala's future

...one in the mouse model. We have identified several novel vaccine proteins that we hope will protect koalas as well." Professor Timms said chlamydia in koalas was a significant cause of infertility, urinary tract infections, and inflammation in the lining of the eye that often led to blindness. "The nu...

Tips from the Journals of the American Society for Microbiology

... diseases. In the study researchers identified a novel parasiticidal peptide named longicin from the tick species Haemaphysalis longicornis and tested its ability to inhibit infection. It showed a remarkable ability to inhibit the blood stage of equine Babesia equi by killing the parasites and resulted ...

Immune system 'escape hatch' gives cancer cells traction

...n turned to Schneck, who in 1993 developed several novel proteins to test how various antigens, such as those on cancer cells, specifically latch on to T cells. Researchers then began experiments to determine if the MDSC T-cell interference was simply genetic or had some biochemical explanation, testin...

HWI researchers determine structure of protein from pathogen associated with CF and TB

The structure of a novel protein in the bacterium that is the most persiste...y is the first structural characterization of this novel protein that is present in many bacteria including the pathogen that causes tuberculosis. It's wel...

EPA foregoes opportunity to improve nanotechnology oversight

...s essential that EPA move quickly to recognize the novel biological and ecological characteristics of nanoscale materials. It can do this only by using the new uses provisions of TSCA, a subject not mentioned in the EPAs inventory document. With the approach outlined by EPA and because of the weaknesses in...

Major breakthrough in understanding how HIV interferes with infected cell division

...sion. Dr. Cohen and his team have identified a novel cellular protein complex targeted by HIV-1 Vpr to stop infected cell division. This protein complex, designated DDB1-CUL4-VprBP, is involved in a process called ubiquitination. Ubiquitination is a mechanism by which a small protein called ubiquitin i...

Insulin sensitizer also serves as energy-conserving signal to the brain

...ition of the chemical in the brain may represent a novel therapeutic strategy for obesity and obesity-linked diseases, he added. White adipose tissue (WAT) is a major site of energy storage and plays an important role in energy balance, the researchers said. It is also recognized as an important endocri...

New blood test might offer early warning of deep belly fat

...ents of RBP4 serum concentrations might serve as a novel biomarker for visceral obesity and increased risk for type 2 diabetes and other adverse outcomes of visceral obesity, said Blher. In addition, pharmacological interventions that reduce RBP4 levels might be a new approach in the treatment of metabolic...

Tiny tweezers and yeast help St. Jude show how cancer drug works

...tion of DNA supercoiling kills the cellsprovides a novel model for how topotecan works; and it provides insights into the drugs action that could help scientists in the clinical development of these agents. A report on this work appears in the advanced, online issue of Nature. This is the first time that...

A gene that protects from kidney disease

...he molecular mechanisms underlying NPHP opening up novel ways to treat the disease. Our mice show striking similarities with NPHP patients, says Mathias Treier, group leader at EMBL. Very early on in their lives their kidney cells start to die and the mice develop all the characteristic disease symptoms....

UF scientists work to develop simple bladder cancer test

...t the University of Michigan. The development of novel non-invasive methods for early detection of bladder cancer is very exciting and represents a major step in (making) routine screening of patients with urological disease feasible in the future, said Nicholas C. Popescu, chief of the molecular cytogen...

Birds take cues from their competitors

...ent Biology, a Cell Press publication. Through a novel field experiment, the researchers showed that fema...rs of two migrant flycatcher species can acquire a novel preference for nesting sites on the basis of the apparent attraction of competing resident tits for ...

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(Date:7/24/2014)... different effects on different species of fish, according ... Bristol and Exeter which tested fish anti-predator behaviour. ... flying seagull predator model when exposed to additional ... minnows. , Lead author Dr Irene Voellmy ... levels in many aquatic environments have increased substantially ...
(Date:7/24/2014)... meaning the microbial populations found on surfaces in the ... final flavor according to research published ahead of print ... This is the first time investigators have taken a ... sake makers inoculate with both bacteria and yeast, says ... California, Davis, but he and his colleagues investigated a ...
(Date:7/24/2014)... NJIT this week for an all-day public forum on ... Agency (EPA) to dredge toxic sediment from an eight-mile ... has called the plan, which proposes removing 4.3 million ... the riverbed, one of the largest cleanups in the ... disposed off-site. , "We need to ensure the future ...
Breaking Biology News(10 mins):The microbes make the sake brewery 2Experts Weigh the Pros and Cons of a $1.7 Billion EPA Cleanup Plan for the Passaic River at an NJIT 2
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