Tag: "novel" at biology news
JCI table of contents: June 21, 2007
...ardiac stem cells" The authors have delineated a novel
and essential pathway for the expansion of recentl...d heart failure and as such it may be a target for novel
therapeutic intervention. Title: Cardiac autophagy is a maladaptive response to hemodynamic stress...
Researchers pit novel version of common virus against cancer
...at the University of Rochester, began looking at a novel
approach to cancer treatment after investigating HIV/AIDS. Even though HIV and cancer are unrelated illnesses, they discovered a common link in the deadly efficiency of HIV cells and cancer cells. Cancer cells are known to have a high concentration...
Researchers develop buckyballs to fight allergy
...ng because it points to the possibility that these novel
materials can one day lead to new therapies, said Chris Kepley, Ph.D., M.B.A., assistant professor in the Department of Internal Medicine, Division of Rheumatology, Allergy and Immunology at the VCU School of Medicine. Researchers in many fields ar...
Developer of new method for treating bone defects wins WPI Entrepreneurship Award
...p further development and commercialization of the novel
technology. The Kalenian Award was established in 2006 by Alba Kalenian in memory of her late husband, inventor Aram Kalenian '33. Its purpose is to encourage innovation and entrepreneurship among WPI students, faculty, and alumni by providing seed...
Surprising origin of cell's internal highways
... these microscopic fibers. The findings point to a novel
cellular mechanism that may guide cell movement an...ery," she said. In addition to identifying this novel
site of microtubule nucleation, Kaverina and colleagues also examined the molecular mechanisms gover...
Ossur's PROPRIO FOOT takes the Gold 2007 Medical Design Excellence Award
...velopment team, which is also responsible for such novel
products as the Unloader One Osteoarthritis Knee Brace, is receiving this recognition. The PROPRIO FOOT, the latest in Ossurs Bionic Technology platform, is the worlds first motor-powered and intelligent prosthetic foot, a seamless fusion of electr...
Giant magnetocaloric materials could have large impact on the environment
...oric effect of these materials. By combining the novel
experimental results with detailed numerical calcu...iting new opportunities towards the engineering of novel
magnetic materials with predictable properties."...
Bee researcher at Arizona State University is 1 of 20 new Pew Scholars in the biomedical sciences
...heimers and Parkinsons disease, and development of novel
treatments has high priority in biomedical research, says Amdam. Although she describes this line of discovery as risky, its prospective contribution is of considerable relevance for human health....
PINK1 protects from Parkinson's
...and promote cell survival. These findings reveal a novel
anti-apoptotic signaling pathway that is disrupted by mutations in PINK1. This study suggests that this pathway has a role in PD pathogenesis and may be a target for therapeutic intervention. ...
Potent possibilities for parasite attack
... given us a short-cut to a small number of largely novel
genes," explained Dr Chris Peacock, first author on the report. "Given their lack of similarity to human genes, they present a limited repertoire of potential targets for drug and vaccine development allowing researchers to optimise the use of limite...
Plastic that grows on trees
...purities.To achieve this, they experimented with a novel
non-acidic catalytic system containing metal chlor...ens the way for fundamental catalysis science in a novel
solvent. The chemistry at work remains largely a mystery, Zhang said, but he suspects that metal c...
Muscle weakness: New mutation identified
...hed in The Journal of Physiology, has identified a novel
mutation associated with muscle weakness and distal limb deformities. The study demonstrates that muscle weakness experienced by persons with a regulatory protein tropomyosin mutation is directly related to a mechanism by which the mutant tropomyosin...
Pre-cancerous blood diseases can be products of their environment
... The new understanding could help pave the way to novel
therapies, according to the researchers. For instance, the findings provide an explanation for why normal blood-forming stem cells transplanted into patients with the myeloproliferative condition sometimes take on the characteristics of the disease t...
JCI table of contents: June 14, 2007
...he enzyme phospholipase C. The results represent a novel
mechanism through which trypsin or tryptase released in response to tissue inflammation may trigger the sensation of pain through PAR2 activation. Therefore, compounds acting on TRPA1 or interfering with the interaction between TRPA1 and PAR2 may be ...
Screening approach leads to discovery of gene linked to breast cancer
BOSTON -- Using a novel
three-part screening process, scientists at Dana-Farber Cancer Institute have identified a gene that is made inappropriately in about a third of all breast cancers. The discovery, reached in collaboration with researchers at Brigham and Women's Hospi...
Could fungal collection hold the key to new life-saving drugs?
...tastic source of fungal samples. We hope that this novel
source of chemical diversity will contain new compounds that can be used to point the way to new drugs for serious diseases. CABI currently uses its fungal collection, along with the expertise of its scientists to offer a range of services to busin...
Small, self-controlled planes combine plant pathology and engineering
...hypothesize that some airborne microorganisms have novel
biochemical processes for interacting with each other as a community of organisms in the atmosphere. He explained, We know that microbes mediate important biochemical processes in the soil and the ocean. It is not so farfetched that a similar drama u...
ENCODE map changes view of the human genome landscape
...ted analysis of experimental datasets reveals many novel
promoters in 1% of the human genome. Genome Res. 1... regions: associating transcription with known and novel
loci. Genome Res. 17: 732-745. (doi:10.1101/gr.5696007) ...
Herpes virus hijacks DNA repair process
...e helps viral replication may enable us to develop novel
strategies to treat infection." The paper appears online this week in Cell Host & Microbe. Scientists have known for some time that viral infection of cells activates the DNA damage response. But researchers had assumed that this activation occurred...
The wider view from a detailed focus
...eserts'. "A major surprise was that many of the novel
control regions are not shared with other speci...d can be used to predict better the location of novel
genes. "Specific types of modifications of the histone proteins near gene starts are a strong ...
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