Tag: "nucleus" at biology news
Promising cell protein may play role in infection and dry eye
...I-2 and the tumor suppressing gene Rb2/p130 in the nucleus
of the epithelial cells in the cornea and conjunctiva. According to the researchers, this interaction with Rb2/p130 and chromatin modeling enzymes may affect how PAI-2 is expressed. "There is a different expression of the protein between the epithel...
Biological motors sort molecules one by one on a chip
...ns that extend in a star-shaped formation from the nucleus
of the cell to the walls of the cell. Molecular bio-motors, such as the enzyme kinesin, can walk in small steps (of 8 nanometers) with a load of material along these microtubule-networks and thus provide transport within the cell. Fascinated by the...
Interfering RNA silences genes in 'slippery' immune cells
...cal agent that inserts itself into a target cell's nucleus
more efficiently than an unaccompanied cassette. The researchers first tested their approach by introducing a gene for green fluorescent protein into human T cells, and using siRNA to inhibit that gene's expression, and dim its fluorescent glow. Th...
Scientists discover new regulating mechanism in cells
...formation. Then, the message travels from the cell nucleus
to another location, the cell cytoplasm. Last, other cell machinery translates the message and assembles the protein. The findings by Boris-Lawrie and her collaborators show that RHA can play an important role in determining whether the last step of...
Novel enzyme offers new look at male hormone regulation
...es. "Human genes are so tightly compact within the nucleus
that if the DNA of a single cell were unwound and stretched, it would be a line of about two meters in length. Histones are necessary to package the DNA so that it fits inside a cell's nucleus," said senior author Dr. Yi Zhang, professor of biochemis...
No-mow grass may be coming to your yard soon
...eroid hormones use to exert their influence in the nucleus
of a cell, where gene expression is regulated, is ...r. Perception then regulates genetic events in the nucleus
in a more roundabout way, similar to a well-studied pathway in animals known as the Wnt signaling pa...
Founding member of Pitt's Biology Department to be honored in Harrisburg, Pa., ceremony
..." which holds protons and neutrons together in the nucleus
of an atom, first described. Amid these firsts in the fields of biology and physics, Max A. Lauffer became the chair of the newly created Department of Biophysics at the University of Pittsburgh (now known as the Department of Biological Sciences in...
Researchers find protein that silences genes
...opsis, they have shown that HDA6 is located in the nucleus
of Arabidopsis cells, and they have imaged it, characterized it biochemically and defined its role in two cellular activities that help bring about gene silencing. According to Pikaard, genes can be turned off when acetyl groups little two...
Salk scientists untangle steroid hormone signaling in plants
... study clarifies what's going on downstream in the nucleus
when brassinolide signals a plant cell to grow." B...s, and allowed it to migrate or "shuttle" into the nucleus
where it tweaked the activity of genes regulating plant growth. A closer inspection, however, revea...
Targeted virus compels cancer cells to eat themselves
...tale signs of autophagy: bits of virus in the cell nucleus
and autophagic vacuoles -- cavities with residual ...lled by apoptosis show specific damage to the cell nucleus
and DNA, with other cellular organelles preserved, Kondo explains. Cells killed by autophagy have l...
Researchers solve mystery of how nuclear pores duplicate before cell division
...rol the flow of information in and out of a cell's nucleus
double in number to prepare for the split to come... the genome (genetic blueprint) encased inside the nucleus
can continue communicating with the rest of the cell. "This issue is as important to understanding t...
News Tips from The Journal of Neuroscience
...searchlight" hypothesis for the thalamic reticular nucleus
(TRN). The TRN consists of a thin layer of GABAerg...eive excitatory inputs from the lateral geniculate nucleus
(LGN) and cortex and send inhibitory output back to the LGN. The authors recorded spike rates of ind...
Movement of chromosome in nucleus visualized
...had no way to track chromosome movement inside the nucleus
or to determine whether the location of the chromo...UIUC researchers show that chromosomes in the cell nucleus
are capable of directed, long-range movement that depends on actin and myosin, the major molecular m...
Insects that produce males from unfertilized eggs reveal a surprising cellular feat
...l hundred accessory nuclei that look much like the nucleus
except that they don't contain chromosomes. Late in the development of the egg cell, the accessory nuclei disintegrate and centrosomes appear in the same locations in the cell. "Right before the egg is laid, the membranes of the accessory nuclei brea...
Novel nuclear function of clathrin
...machinery, directly interacts with p53 in the cell nucleus
to promote expression of p53 target genes. Dr. Taya anticipates that "this finding may open a new unexpected research field that connects p53, endocytosis and tumorigenesis."...
Stress-induced levels of corticotropin-releasing factor responsible for binge behaviour
...ey injected the rats in a part of the brain called nucleus
accumbens, known to be involved in the mediation of both pleasurable rewards and stress signals in humans as well as rats. They observed the behaviour of the rats in response to a cue a 30-second long tone- that had previously been associated with t...
Salk scientist Ron Evans wins 2006 Gairdner Award for his discovery of hormone sensors
...g an urgent message, cortisol sweeps into a cell's nucleus
where it is met by molecules called nuclear receptors. They grab the cortisol molecules and together they clamp down in specific places on the chromosomes, where they tweak the activity of genes. The discovery of the receptor for cortisol provided th...
Researchers look to the brain to explain gender differences in sleep apnea
...ed that either the caudal raphe or the hypoglossal nucleus
-- or both together -- play roles in sleep apnea. ...nin expression in the caudal raphe and hypoglossal nucleus
-- leading to a difference in tongue control. The researchers hypothesized that females would have ...
Omega-3 fatty acids inhibit growth of liver cancer cells
...plitting up, or cleavage, of an enzyme in the cell nucleus
known as poly (ADP-Ribose) polymerase, or PARP, which is involved in repairing DNA damage, mediating apoptosis and regulating immune response. The cleavage of this enzyme is considered a tell-tale indicator of apoptosis. Furthermore, DHA and EPA trea...
First direct mechanical communication of mitochondria, cardiomyocyte nucleus shown
... mechanical communication between mitochondria and nucleus
in cardiac cells," was chosen to be part of the "Physiological Genomics of Skeletal Muscle Adaptation in Health and Disease" Featured Topic session 199, sponsored by the APS Muscle Biology Group. Sunday April 2 at 10:30 a.m. in the Convention Center,...
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