Gene regulation, not just genes, is what sets humans apart
...have contributed to the current human pandemics of obesity and diabetes, and perhaps there will be some insights from understanding how these regulatory sequences have evolved, he said. To do a genome-wide analysis of regulatory regions, Haygood and post-doctoral fellow Olivier Fedrigo had to adapt some o...Research shows skeleton to be endocrine organ
...ty prevents the development of type 2 diabetes and obesity in mice. This discovery potentially opens the door for novel therapeutic avenues for the prevention and treatment of type 2 diabetes. The discovery that our bones are responsible for regulating blood sugar in ways that were not known before complet...Study suggests estrogen deficiency can lead to obesity-induced high blood pressure after menopause
...n a third of their life in menopause. In addition, obesity is increasing dramatically in all populations and ...ter menopause may contribute to the development of obesity and hypertension, opening new therapeutic approaches to postmenopausal hypertension. ...JCI table of contents: August 1, 2007
...teady The increasing number of individuals with obesity and diabetes has made understanding the regulation...re "needed to combat the growing problems that are obesity and diabetes." TITLE: AMPK is essential for energy homeostasis regulation and glucose sensing by P...Negative effects of plastic's additive blocked by nutrient supplements
...outi mice are at a much greater risk for diabetes, obesity and cancer. The fact that the mice fed BPA had a...d, that the reason Asians have much lower rates of obesity and certain cancers is that their diet typically includes greater use of soy products than Western d...Monell researchers find metabolic defect in liver that can lead to obesity
...ally-transmitted metabolic defect that can lead to obesity in some individuals. The defect involves decreased...ecome obese while others remain thin. The global obesity epidemic is thought to be caused in part by the increased availability and intake of high calorie fo...Adult survivors of childhood leukemia exercise less, worsening high risk for obesity and illness
...d. The storyline is that physical inactivity and obesity outcomes are based upon type of therapy administered to patient, said Dr. Oeffinger. Importantly, there are things we can do to intervene and to help childhood cancer survivors to regain active lifestyles that will protect the patient in the long run...New role for protein in fat cells may improve understanding of obesity and diabetes
...a result, probably has unexpected contributions to obesity and diabetes. CETP is known to shuttle differen...tores and regulates fats and of conditions such as obesity and diabetes....JCI table of contents: July 19, 2007
...uscle PKC-lambda, is sufficient to cause abdominal obesity and other abnormalities characteristic of the metabolic syndrome and type 2 diabetes. TITLE: Muscle-specific knockout of PCK-lambda impairs glucose transport and induces metabolic and diabetic sydnromes AUTHOR CONTACT: Robert V. Farese Universi...Obesity found to be a risk factor for multiple myeloma
...h has identified possible biological links between obesity and multiple myeloma. For example, adipocytes, ce...oma. The IL-6 chemical pathway is one possible way obesity could influence the risk of developing diseases like cancer or cardiovascular disease, but the answe...Losing weight after pregnancy -- diet and exercise better than diet alone
... body weight may be one factor that contributes to obesity among women. Many women are keen to find ways of returning to, and maintaining, pre-pregnant weights, and there is plenty of competing advice on offer. By studying data from six different trials that involved a total of 245 women, a group of Cochra...Metabolic syndrome -- don't blame the belly fat
...ther confounding factors typically associated with obesity and type 2 diabetes, which have been thought to pl...esistant individuals, was independent of abdominal obesity and circulating plasma adipocytokines, suggesting that these abnormalities develop later in the deve...Study shows cane sugar, corn sweeteners have similar effects on appetite
...h of the evidence that linked corn sweeteners with obesity came from animal-based metabolic studies using pure fructose. This study, on the other hand, used beverages sweetened with two types of high-fructose corn syrup: HFCS 55, which contains about 55 percent fructose and 45 percent glucose; and HFCS 42, w...Scientists find brown fat master switch
...of adipose tissue that generates heat and counters obesity caused by overeating. A team headed by Bruce Spi...ith PRDM16 and implanting them in mice works as an obesity preventive, the investigators say a similar intervention is theoretically possible in people. "You m...Study finds Western-style 'meat-sweet' diet increases risk of breast cancer in postmenopausal women
..., there seems to be a specific interaction between obesity and western cuisine among postmenopausal women tha...ibility that the meat-sweet pattern interacts with obesity to increase breast cancer risk, Tseng said. Low consumption of a western dietary pattern plus succe...Insulin sensitizer also serves as energy-conserving signal to the brain
...ain may represent a novel therapeutic strategy for obesity and obesity-linked diseases, he added. White ad...hat decreased circulating levels of adiponectin in obesity and type 2 diabetes may contribute to the insulin resistance that characterizes both conditions. I...New blood test might offer early warning of deep belly fat
...ions might serve as a novel biomarker for visceral obesity and increased risk for type 2 diabetes and other adverse outcomes of visceral obesity, said Blher. In addition, pharmacological interventions that reduce RBP4 levels might be a new approach in the treatment of metabolic syndrome and visceral obesity....Fat horses face health problems
Blacksburg, Va. --Americas growing obesity problem has alarmed physicians and public health o...macro-molecules. Other problems caused by equine obesity are heat stress, increased bone, tendon, and joint injuries, and reduced performance levels. After...Common environmental chemicals in diet affect fetal ovarian development
...uch measures helped to reduce the rates of cancer, obesity and infertility, there would be considerable benefits in terms of the costs of healthcare.......y. As well as genetics, other risk factors such as obesity and hormone replacement therapy probably play a role in the incidence and outcome of breast cancer. Dr Hartman says the findings are relevant to women with newly diagnosed breast cancer, and to those treating them. The next step will be to understand...