Joslin study reveals how a specific fat type can protect against weight gain and diabetes
... diabetes, while others are more likely to develop obesity and this most common form of diabetes on any diet....t may account for why some mice are protected from obesity and diabetes and others are not. This study began by exploring differences in basal energy expendi...'Bridge' protein spurs deadliest stages of breast cancer
...d examines signaling pathways that are involved in obesity and diabetes, has studied the roles played by Gab-2 and its chemical cousin Gab-1, in various disorders. His fundamental analyses of cell signaling for Gab-2 led him to study the protein in cancer cells. Feng and his colleagues began by examining Gab......function may be altered to make them more prone to obesity and disease. "Certain environmental substances c...n remained thin. This is a serious problem because obesity puts people at risk for other problems, including cancer, diabetes, cardiovascular disease and hyper...JCI table of contents: February 15, 2006
...yndrome (MetS), a collection of disorders (such as obesity and insulin resistance) that lead to increased risk of developing type 2 diabetes and heart disease. A protein known as PPAR-gamma has been shown to be affect most aspects of MetS. However, these studies have had to focus on the affects of PPAR-gamma...Breakthrough in understanding type 2 diabetes as key genes identified
...jor reasons why people develop type-2 diabetes are obesity and a family link. Our new findings mean that we can create a good genetic test to predict people's risk of developing this type of diabetes. "If we can tell someone that their genetics mean they are pre-disposed towards type-2 diabetes, they will ...A unique twin study on the increased cardiometabolic risk in obesity
...ted to central and intra-abdominal depots and when obesity is accompanied by an atherogenic dyslipidemia. ...ds with anti-oxidative properties. The origin of obesity and related dyslipidemias is multifactorial, involving complex genetic and environmental networks. N...Scripps research team discovers a chemical pathway that causes mice to overeat and gain weight
...or." Bartfai notes, "Inflammation as part of the obesity and metabolic syndrome is being recognized to an i... for determining the importance of inflammation in obesity and in the conversion of obesity to type 2 diabetes." Ultimately, better understanding of the role...Improved imaging for identifying breast cancer in overweight women
...f surgical management approaches in breast cancer, obesity is a significant factor in why it fails and inevitably leads to occasionaland unnecessaryfull axillary lymph node dissection (a more complex surgery that removes all lymph nodes in the armpit region)." Breast cancer is the second leading cause of c...Researchers discover master metabolism regulator with profound effect on fat metabolism
...ntal disorders, or even death. On the other hand, obesity is reaching near-epidemic proportions in wealthier nations. According to the Centers for Disease Control, 30 percent of U.S. adults over the age of 20 are obese.[2] Rather than working with cells in culture, Guo and Cavener examined metabolic proc...JCI table of contents: Feb. 1, 2007
...he body) has been implicated in the development of obesity and the metabolic syndrome in humans. Further evid...t provide therapeutic targets for the treatment of obesity and the metabolic syndrome. In an accompanying commentary, Liangyou Rui from the University of Mich...Natural fiber may take extra pounds away
... help achieve a healthy body weight. It won't cure obesity or cause people to drop half their body weight -- not even our strongest obesity drugs can do that -- but we believe it could help." The fibre is called oligo fructose. "It's not ...MU researchers to study how changes in infrastructure affect physical activity behavior
...obert Wood Johnson Foundation. "We are facing an obesity epidemic in our country," said Steve Sayers, assis... Physical activity is vital in the prevention of obesity and chronic diseases such as diabetes and heart disease, but over the past 50 years, physical activi...Weight-loss supplement shows good and bad traits
..." Belury said. "Lowered levels are associated with obesity and type 2 diabetes." The researchers found that...y pointed out that up to 75 percent of people with obesity and diabetes develop an illness called non-alcoholic fatty liver disease in which fat accumulates in...Major link in brain-obesity puzzle found
...ction in fat tissue, leading to the development of obesity in mice that lack SH2B1 in both locations. Rui ... to better tactics for understanding the causes of obesity and its consequences, including Type 2 diabetes, and perhaps better methods for preventing and rever...Joslin-led study uncovers role of appetite hormone MCH in insulin production
...r Joslin-led study examined the connection between obesity and MCH, which plays a critical role in energy balance and appetite, observing an increase in the number of beta cells when MCH levels are high. This was a new finding that had not been observed before. Although MCHs role in appetite control is well ...JCI table of contents: January 25, 2006
... it is becoming clear that inflammation induced by obesity is an important factor linking obesity to type 2 diabetes, the effects of one of the most abundant soluble factors known to have both anti-...Mind over matter: SH2B1 in the brain regulates obesity
... of research for the development of treatments for obesity and type II diabetes. In the study, which appears... obese. It also prevented the mice from developing obesity after being fed a high-fat diet, indicating that SH2B1 in the brain is required to regulate body wei...Like salty food? Chances are you had low blood sodium when you were born
...dren about the increased risk of sodium intake and obesity later in life....JCI table of contents: Jan. 18, 2007
...CK: Mind over matter: SH2B1 in the brain regulates obesity Obesity is one of the main risk factors for deve... of research for the development of treatments for obesity and type II diabetes. In the study, which appears online on January 18 in advance of publication in......me Trust) Natural gut hormone offers hope for new obesity drug Professor Steve Bloom (Imperial College London) New antibacterials being developed to tackle MRSA Dr Lloyd Czaplewski (Prolysis) Novel approach to cancer drug Professor Jeremy Tavar (University of Bristol) To attend, please RSVP to c.br...