University of Pittsburgh gets wired for speed with Apple Xserve G5 cluster
...e." Trying to sort out genuine risk from arbitrary observation stretches the limits of old statistical methods, Dr. Whitcomb added. "We are looking at the possible interactions of multiple genes and environmental factors in our group of patients," he said. "There are thousands of possible genetic and environment...Unchecked DNA replication drives earliest steps toward cancer
...an cancers, for example. The Wistar team's primary observation is that an initiating genetic error can push a cell to divide relentlessly, leading to conditions of DNA replication stress. This stress leads to random errors in the DNA duplication process breaks in the DNA that disrupt genes, for example. Unless ...Signs of aging: Scientists evaluate genes associated with longevity
...tre and first author on the study. Another notable observation was that stress-response factors such as hsp, mtl-1, gst-1, and sip-1 were more abundantly expressed in the aging adult worms as compared to the early and mid-life adults. These genes were also differentially expressed between daf-2 mutants and cont...Green tea shown to prevent prostate cancer
...derives from traditional Chinese medicine, and the observation of lower cancer rates among Asian populations. Bettuzzi observed that the Mediterranean diet is rich in vegetables, and lower rates of prostate cancer are found in that region, as well. The 600 mg-per-day dosage of caffeine-free, total catechins (50 ...A decade after launch, ERS-2's mission continues
...an and international missions to provide long-term observation of key environmental variables. The mission's well-defined products and services are playing an important role in initial services of GMES, and this is expected to continue until the new generation of operational Sentinel spacecraft are deployed. Ex...Wisconsin researchers identify sleep gene
...legs as the insects recovered from anesthesia. The observation led the team to focus on the Shaker gene, which produces this effect. Nevertheless, Shaker's main job in flies-and in its equivalent in humans--is to control the excitability of cell membranes. Genetic analysis of the mns flies, conducted by Daniel B...Research on antibiotics receives historical recognition
...scovery of penicillin, which came through a chance observation by Alexander Fleming, who noted that a mold contaminant on a Petri dish culture had inhibited the growth of bacteria. Streptomycin was the third antimicrobial agent isolated under Waksman's direction at Martin Hall at Cook College, Rutgers Universit...Atmosphere may cleanse itself better than previously thought
...g OH radicals at low ultraviolet wavelengths. This observation has eluded science primarily because photochemistry at these wavelengths has been difficult to study. "Thanks to an innovative laser technique that at last allows us to observe these chemicals in action, we now theorize that the atmosphere may produc...Waggle dance controversy resolved by radar records of bee flight paths
...ists watched the waggle dance occurring in a glass observation hive and identified recruits. They captured these recruits as they left the hive, attached a radar transponder to them and then tracked their flight paths using harmonic radar. Most recruited bees undertook a flight path that took them straight to th...Ancient immune defense mechanism is no match for HIV-1
...RS also helps explain the long-standing biological observation that when HIV-1 is engineered to be lacking Tat but contains alternative transcriptional activators, it fails to spread productively in human cells." The researchers also suggest that their findings raise a challenge to proposed therapeutic strategi...Tracking a killer: Observing liver invasion by malarial parasites
...cycle invasion of the liver - have escaped direct observation until now. In their new study published in the ope.... used intravital microscopy - which allows direct observation of events in a living animal - to study the discrete steps that facilitate the parasites' entry into...Scientists journey to southern Africa to unravel the secret world of elephant communication
... cooking/dining area and a 20-foot-tall, two-story observation tower with a commanding view of the waterhole and ...to a tape deck installed in the upper level of the observation tower 100 yards away. Every time a herd showed up at the waterhole, O'Connell-Rodwell would pop a ta...Single gene is genetic switch for fly sexual behavior
...at all" when paired with virgin female flies in an observation chamber, according to the researchers. Males with the female fruitless splice form were also more likely to court other males than flies with the male form, suggesting that male-specific fruitless splicing "not only promotes male-female courtship, it...From memory formation during sleep to novel components for physics
...ventative and therapeutic strategies. Based on the observation that children who grow up in a rural setting and are subjected to harmless bacteria and dust are less susceptible to allergies and asthma, the group aims to study how susceptibility to allergies arises and what role is played by the key mechanisms of...JCI table of contents July 1, 2005
... activation of antigen-presenting cells is a novel observation that, and this trigger might account for the hyperactivity of T cells and break in self-tolerance seen in lupus. This new information has important implications towards our understanding of autoimmune disease, and how to manage it clinically. Title:...Space measurements of carbon offer clearer view of Earth's climate future
... they fit with observed reality." While satellite observation of the greenhouse gas carbon monoxide is well esta...actions needed to create a semi-operational carbon observation system during the coming decade. Roger Dargaville of IGCO stated that satellite systems would be an...Lance Armstrong through a physiological lens: hard training boosts muscle power 8%
...li that provided this adaptation, are unclear. The observation that both gross and delta efficiency improved to the same extent and also with the same time course suggests an improved efficiency of ATP turnover within muscle fibers during contraction." (ATP, or adenosine triphosphate, is a nucleotide present th...Interim data suggest major response with Aranesp(R) in anemic patients with MDS
...oup had a least one transfusion during the 13-week observation period. "In these interim results MDS patients who have never been treated for their anemia responded to Aranesp and those who had prior erythropoietic therapy continued to respond," added Gabrilove. "There are currently no recombinant erythropoieti...JCI table of contents August 1, 2005
...d LDL may be involved in fat cell metabolism. The observation suggests that anti-diabetic drugs that are also PPAR gamma ligands may be beneficial in individuals with metabolic syndrome/ insulin resistance by enhancing lipid uptake into the adipocytes and suppressing release of inflammatory factors. Title: PPA......nces of survival. "One possible mechanism for this observation is increased damage of mitochondria in cadmium-exposed oysters with increasing temperature", Lannig explains, "these organelles become significantly more sensitive to cadmium as temperature rises, so that cadmium levels which were not damaging to mit...