NIH awards new $14.5 million, five-year grant to the Scripps Research Institute
...und the problem for years with tricks like lopping off the portion of the protein that is on the outside of the cell membrane and solving it as one would any soluble protein. But the problem with this is that it ignores what happens inside the membrane -- where some of the most important biological actio...New therapy for specific form of leukemia
...h a flaw at the ABL1 gene, a piece of DNA is split off and 'takes on a life of its own' as it were. This fragment contains the ABL1 gene, connected to another gene. Due to this fusion, ABL1 works non-stop − stimulating cell growth unremittingly. This process leads to an uncontrolled growth of immat...Commandeering cellular machinery: recognition mechanism to detect small molecules
...goal of creating pharmaceuticals able to turn them off or on. The research often involves placing nuclear receptors into yeast cells, which because they do not have nuclear receptors of their own, allow scientists to isolate the activities of specific receptors. For their study, Doyle's team chose the n...College students recognized & rewarded for their innovative work
...plied pressure, his device can pump, mix, and shut off flow. A native of Ann Arbor, Gu is a senior chemical engineering major at the University of Michigan. His advisor, Dr. Shuichi Takayama, receives a $5,000 prize. Graduate winners Jwa-Min Nam , 30, and Shad Thaxton , 28, of Northwestern University......dies showing how and when various species branched off the family tree of primates and humans. Second, it...ree for lice showing when various species branched off from each other. Genes of modern lice also were used to reconstruct their population histories over ...How roots control plant shoots
...ntly producing the carotenoid byproduct that turns off leaf growth. First, they grew thale cress plants...iment." She grew mutant seedlings, cut their roots off and placed the shoots on agar, a gelatinous substance containing nutrients. Those mutants produced t...New Stanford center probes nanoscale material
...ach high school, a lot of them have already turned off [to science]," Moler said. The center is interdisciplinary, with faculty from many departments represented. Hongjie Dai from the Chemistry Department, for example, has developed a wafer-scale process for fabricating carbon nanotubes on the end of sil...New Military Biomaterials R&D Center to hold first meeting
...the military's most urgent healthcare needs on and off the battlefield. One of the first technology platforms the CeBMR is supporting is a sprayable wound dressing designed to enable soldiers to treat their own small gunshot wounds, burns, abrasions or cuts, so that they may complete a three-day missio...Old bones unearth new date for giant deer's last stand
...rs or so, we still can't tell what actually killed off these beasts. Man could have been the ultimate des...quirements for the antlers alone might have killed off the species. Traditionally, woolly mammoths were believed to have gone extinct around the same time ...Society for Psychophysiology Research
...ecent studies suggest that expressive writing sets off a cascade of cognitive, emotional, biological, and social shifts in people's lives resulting in better physical health, improved social connections with others, and enhanced positive moods....UCR researchers identify key plant enzyme that defends against multiple infections
...h, an important process plants undergo in fighting off bacterial, fungal or viral infections. The develop..., which are dependent on plants being able to fend off multiple types of pathogens. The findings, outlined in a paper titled "VPEg Exhibits a Caspase-like...T cell's memory may offer long-term immunity to leishmaniasis
...ay lead to the development of vaccines that fight off a range of pathogens that respond well to a helper T cell response. ...World's top theoretical physicists converge to consider 'future of physics'
...the lone thinker. The two-story addition closes off the courtyard to exterior access, thereby adding t... in the original building, offices are placed only off one side of the wing that extends towards the ocean. That wing ends in the most distinctive feature...Researchers provide road map for generating B cells from stem cells
...em to respond to signals yet to come, and blocking off other options. "Our findings reveal considerable complexity, but are promising from the standpoint of directing stem cell differentiation," said Harinder Singh, Ph.D., Louis Block Professor of Molecular Genetics and Cell Biology and an Investigator w...New method identifies chromosome changes in malignant cells
.... When a group of genes appears to be turned on or off together, biologists often look for a master regulator that controls them all at once. "They can write whole papers about how interesting it is that they are regulated together, when in fact what is happening is that the whole chunk of the chromosome...UF scientists have bionanotechnology recipe to find elusive bacteria
...al means could take days and would involve sealing off the entire area during that time, he said. "Instead, we can come back in 20 minutes and say either this is safe or there is a problem." Chad Mirkin, professor of chemistry at Northwestern University and director of Northwestern's Institute for Nanote...Touching research: How white blood cells navigate
...ctivated. Signals from moment to moment turn on or off the Velcro from place to place, determining exactly when and where cells stick and accumulate. When some adhesion molecules are activated, cells begin to roll slowly along a blood vessel wall; when others turn on, the cells are snagged by the blood v...Laboratory test of evolutionary theory confirms importance of links between populations
...tubes that provide nutrients and oxygen and siphon off wastes. In one set of chemostats the communities remained isolated from one another. In another set, Forde periodically made a series of transfers between communities, sucking up a pipette full of bacteria and viruses from one chemostat and adding it...Purdue chemists give an old laboratory 'bloodhound' a sharper nose
...t like a strong wind kicks up dust, the gas breaks off a few small particles of the unknown substance, and these combine with the reactive chemicals to form an ionized compound that a mass spectrometer can analyze right then and there. It can be done anywhere, and because there are fewer intervening step......ncorporation of substances into a cell by pinching off of the plasma membrane. The Lin study is based on the fruit fly model (Drosophila). He and his colleagues studied the fruit fly protein called Decapentaplegic (Dpp). Dpp is a morphogen molecule that is similar in structure to the human TGF beta p...