Breast cancer prognosis runs in the family
...also runs in the family. Research published in the online journal Breast Cancer Research suggests that if a woman succumbs to breast cancer her daughters or sisters are over 60 percent more likely to die within five years if they develop the disease. Mikael Hartman from the Karolinska Institute in Stockho...'Modular' leukemia drug shows promise in early testing
...iversity Comprehensive Cancer Center was published online in the journal Blood. Our findings have significant implications for the treatment of CLL and related malignancies, says principal investigator John C. Byrd, director of the hematologic malignancies program at Ohio State 's James Cancer Hospital a...New genetic test developed at Emory advances detection and diagnosis of muscular dystrophy
...ion and nonfunctional proteins. New data published online in the current edition of the journal Nature show that PTC124, an investigational new drug designed to bypass dystrophin nonsense mutations and restore a functional protein, was effective in a preclinical (animal) model of Duchenne muscular dystrophy...Sentinel lymph node biopsy is associated with breast cancer rates
... clinical practice, according to a study published online June 26 in the Journal of the National Cancer Institute . Deirdre Cronin-Fenton, Ph.D., of Aarhus University Hospital in Denmark, with colleagues at the National Cancer Institute in Bethesda, Md., found that the increase in some early stage breas...Bisphosphonate treatment is associated with jaw bone problems
...ation or infection, according to a study published online June 26 in the Journal of the National Cancer Institute . Several recent studies have found an association between the use of intravenous bisphosphonates and osteonecrosis of the jaw or facial bones, a condition in which poor blood supply to the ...Nanoparticles carry chemotherapy drug deeper into solid tumors
...heir survival time, according to a study published online June 26 in the Journal of the National Cancer Institute . In the past, similar drug carriers have improved targeted delivery of the drugs and reduced toxicity, but they sometimes decreased the drugs ability to kill the tumor cells. Using a new dru...Gene variant increases risk for alcoholism following childhood abuse
... of the study appears in the June 26, 2007 advance online publication of Molecular Psychiatry. Previous studies have shown that childhood sexual abuse increases the risk for numerous mental health problems in adulthood. However not all abused children develop such problems, a likely indication that genet......guins sites in 2005. The research is published online the week of June in Proceedings of the National Academy of Sciences. It was funded by the National Science Foundation Office of International Science and Engineering and the National Geographic Society. The first of the new species, Icadyptes sala...MIT researchers reverse symptoms in mice of leading inherited cause of mental retardation
...autism in mice. The work will be reported in the online early edition of the Proceedings of the National Academy of Sciences the week of June 25-29. The mice were genetically manipulated to model Fragile X Syndrome (FXS), the leading inherited cause of mental retardation and the most common genetic caus...Specialized, bone-crushing wolves of Alaska disappeared long ago
...e, many thousands of years ago, researchers report online on June 21st in the journal Current Biology, a publication of Cell Press. The extinct Alaskan wolves had robust bodies, strong jaws, and massive canine teeth for killing prey larger than themselves and regularly consuming large bones, according to th...Ice Age extinction claimed highly carnivorous Alaskan wolves
... The study, which will be published in the June 21 online issue of Current Biology, combined genetic and chemical analyses with more conventional paleontological study of the morphology, or form, of the fossilized skeletal remains. This multifaceted approach allowed the researchers to trace the ancient wolv...JCI table of contents: June 21, 2007
...ersity School of Medicine in their study appearing online on June 21 in advance of publication in the July p...sue damaged by heart disease. In a study appearing online on June 21 in advance of publication in the July print issue of the Journal of Clinical Investigatio...Hepatitis B drug can compromise HIV treatment
... Medicine. In findings published June 21, 2007, online in the journal, the researchers reported that a patient infected with both hepatitis B and HIV who was treated with entecavir developed a mutant strain of HIV that is resistant to the antiviral drugs lamivudine and emtricitabine. Entecavir is manufac...Researchers develop buckyballs to fight allergy
... with water. The new study findings were published online in the June 19 issue of the Journal of Immunology and will appear in the July 1 print issue of the journal. This discovery is exciting because it points to the possibility that these novel materials can one day lead to new therapies, said Chris Kep...Scripps research scientists show protein accelerates breast cancer progression in animal models
...published the week of June 18, 2007 in an advanced online edition of the Proceedings of the National Academy of Sciences. Until this study, the significance of pleiotrophin (PTN) expression in breast cancer had not been clearly established. These new findings could lead to a better understanding of the mo...Children of smokers have more than 5 times higher levels of a nicotine toxin
...rwick, and the University of Leicester, published online ahead of print in Archives of Disease in Childhood. Having a mother that smokes was found to have the biggest independent effect on cotinine in the urine quadrupling it. Having a smoking father doubled the amount of cotinine, one of chemicals pr...Does stimulant treatment for ADHD increase risk of drug abuse?
...Laboratory. The results appear in the June 5, 2007 online issue of the journal Pharmacology, Biochemistry and Behavior. "Our study shows that the brain's reward pathways are definitely influenced by methylphenidate, one of the stimulant drugs commonly used to treat ADHD," said Brookhaven researcher Panayo...UI anthropologist, colleagues discover remains of earliest giant panda
...o-author of an article published in the June 18-22 online edition of the journal Proceedings of the National Academy of Sciences (PNAS). Previous discoveries of teeth and other remains made between 1985 and 2002 had failed to establish the animal's size. Ciochon says that the ancient panda (formally known...Reconstructing the biology of extinct species: A new approach
... National Academy of Sciences and in the journal's online early edition during the week of 18 to 22 June. "We have shown that there is a fundamental adaptive mechanism linking a species' locomotion with the sensory systems that process information about its environment," says Alan Walker, Evan Pugh Profes...Researchers discover 'acquired' DNA key to certain bacterial infection
...hers at Oregon State University, will be published online this week in the Proceedings of the National Academy of Sciences. Other co-authors were from the University of Nebraska. The key to the bacteriums ability to enter environmental amoebas and ultimately humans is an island of genetic material acqui...