Scientists clone mice from adult skin stem cells
...ear transfer procedure, Li took unfertilized mouse oocytes and replaced the nucleus of each oocyte with a nucleus from these adult skin stem cells. A main hurdle in nuclear transfer with adult cells has been its efficiency out of a hundred attempts, only a handful may succeed with reported success rates...Mouse stem cell line advance suggests potential for IVF-incompetent eggs
Researchers have found that mouse oocytes that fail to become fertilized during in vitro fer...ical concerns surrounding the need for fresh human oocytes for similar nuclear-transfer procedures using human cells. The findings, reported by Teruhiko Wakaya...The cost of keeping eggs fresh for mother cockroaches
... they wait too long to mate they lose good quality oocytes through programmed cell death. But Moore's team finds that some females have genes that would allow them to maintain eggs even if they delay mating. So why aren't all females delaying cell death and holding onto their eggs? Moore speculates that perh...A twist of fate -- Reprogrammed fibroblasts resemble embryonic stem cells
...s cell types, including blood cells in culture and oocytes in animals. Importantly, two related papers being published in the journal Nature demonstrate that similar induced pluripotent cells can also give rise to fertilized embryos and viable offspring, respectively. Future studies are needed to examine whe...Frog molecule could provide drug treatment for brain tumors
...ibonuclease enzyme that has been isolated from the oocytes (egg cells) of the Northern Leopard frog. Ribonucleases are a common type of enzyme found in all organisms. They are responsible for tidying up free-floating strands of RNA cells by latching on to the molecule and cutting it into smaller sections....Extracting eggs from pre-pubertal cancer patients brings hope for future fertility
...had not reached puberty. We were able to extract oocytes using needle aspiration from very young girls, he ... patient. Excluding one patient who asked that the oocytes we had found in her ovaries should be frozen immediately, we matured the 130 others in vitro, said D...Personalized approach to ovarian stimulation achieves high ART pregnancy rates
...starting dose for each patient, both the number of oocytes retrieved and pregnancy rates rose. Professor Fr...nt treatment outcome as testified by the number of oocytes retrieved and the high pregnancy rates. This approach should enable us to improve patient manageme...First baby is born after oocytes were matured in the lab and frozen
...rtilisation of frozen or vitrified and then thawed oocytes that had been collected after ovarian stimulation....-positive breast cancer. In these circumstances, oocytes can be collected from the ovaries without hormonal stimulation, and the immature oocytes can be matu...Germany's embryo protection law is 'killing embryos rather than protecting them'
...d nearly 19 per cent resulted in births when fresh oocytes were used, but the cumulative delivery rate from both fresh and frozen oocytes was 30 per cent. By contrast, in the UK, from 30,495 cycles, 22% of the deliveries occurred after fr...MGH researchers confirm that bone marrow restores fertility in female mice
...ified mechanism. While donor-derived egg cells or oocytes were observed in the ovaries of marrow recipients,... at MGH, the studys senior author. Although these oocytes derived from marrow cells dont appear competent, at least thus far, to make fertilizable eggs, marro...First case of successful ovarian tissue transplantation between two, nonidentical sisters
...er a year, doctors were able to recover two mature oocytes from her ovaries and fertilise them to produce two...r the transplant, the doctors retrieved two mature oocytes from her ovary and fertilised them with her husbands sperm via ICSI (intracytoplasmic sperm injectio......found in all dividing cells. What is special about oocytes is that they lack specialised spindle-forming orga...or a long time we did not understand how mammalian oocytes could assemble a bipolar spindle without such centrosomes. Tracking spindle assembly over time with ...